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hydroxydihydropyrollidinone

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Identification
Molecular formula
C5H7NO3
CAS number
29521-56-4
IUPAC name
4-hydroxy-3,4-dihydro-2H-pyrrole-2-carboxylic acid
State
State

At room temperature, 4-hydroxy-3,4-dihydro-2H-pyrrole-2-carboxylic acid exists as a solid. It is stable under standard conditions of temperature and pressure.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
265.00
Boiling point (Kelvin)
538.15
General information
Molecular weight
129.12g/mol
Molar mass
129.1190g/mol
Density
1.3510g/cm3
Appearence

The compound is typically observed as a crystalline solid. The crystalline nature allows for distinct, ordered structures that can be seen under a microscope. Its color can range from white to off-white, common with many similar organic carboxylic acids.

Comment on solubility

Solubility of 4-hydroxy-3,4-dihydro-2H-pyrrole-2-carboxylic acid (C5H7NO3)

The solubility of 4-hydroxy-3,4-dihydro-2H-pyrrole-2-carboxylic acid is an intriguing aspect due to its functional groups and molecular structure.

Generally, the solubility of this compound can be influenced by several factors:

  • Hydrogen Bonding: The presence of hydroxyl (-OH) and carboxylic acid (-COOH) groups facilitates hydrogen bonding with water, enhancing its solubility in polar solvents.
  • Polarity: With a polar molecular structure, this compound exhibits increased solubility in polar solvents compared to non-polar solvents.
  • Temperature: As with many organic compounds, solubility can increase with temperature—higher temperatures typically promote greater solubility.

It is often found that:

  • 4-hydroxy-3,4-dihydro-2H-pyrrole-2-carboxylic acid is soluble in water due to its hydrophilic nature.
  • In organic solvents, solubility can vary significantly—thus careful selection of solvent is important for applications.

In summary, the solubility characteristics of this intriguing compound make it versatile for various chemical applications, particularly in aqueous environments where it can readily participate in chemical reactions.

Interesting facts

Interesting Facts about 4-Hydroxy-3,4-dihydro-2H-pyrrole-2-carboxylic Acid

4-Hydroxy-3,4-dihydro-2H-pyrrole-2-carboxylic acid, commonly referred to as a pyrrole derivative, presents a fascinating intersection of organic chemistry and medicinal applications. Here are some engaging facts about this compound:

  • Structural Complexity: This compound features a pyrrole ring, which is a five-membered aromatic ring containing nitrogen. This gives it unique properties compared to more common carboxylic acids.
  • Biological Significance: Pyrrole derivatives are often found in a variety of natural products, including amino acids and alkaloids. They play a crucial role in the biosynthesis of important biomolecules.
  • Potential Medicinal Use: Due to its interesting structural attributes, 4-hydroxy-3,4-dihydro-2H-pyrrole-2-carboxylic acid has garnered attention for possible applications in drug design. Compounds featuring similar structures are studied for their antibacterial and antioxidant activities.
  • Research Applications: Chemists are investigating this compound's reactivity, particularly how its functional groups interact during chemical reactions. These insights can lead to novel synthetic pathways in organic chemistry.
  • History & Discovery: The exploration of pyrrole compounds dates back to the early 19th century, with ongoing research continually revealing new applications and reactions that expand our understanding of this fascinating class of compounds.

In conclusion, 4-hydroxy-3,4-dihydro-2H-pyrrole-2-carboxylic acid demonstrates how intricate organic structures can have significant implications in chemistry and biology. The beauty of such compounds lies not just in their molecular make-up but also in their potential to be harnessed for advancements in science and medicine.

Synonyms
4-hydroxy-3,4-dihydro-2H-pyrrole-2-carboxylic acid
22573-88-2
pyrroline hydroxycarboxylic acid
1-pyrroline-3-hydroxy-5-carboxylic acid
3-Hydroxy delta 1-pyrroline-5-carboxylic acid
L-Delta1-pyrroline 3-hydroxy-5-carboxylate
pyrroline-hydroxy-carboxylate
SCHEMBL2510035
CHEBI:27391
DTXSID40865059
AKOS006386793
L-1-pyrroline 3-hydroxy-5-carboxylate
3,4-dihydro-3-hydroxy-2H-pyrrole-5-carboxylic acid
Q27103102
2H-Pyrrole-2-carboxylic acid, 3,4-dihydro-4-hydroxy-