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4-hydroxy-3,5-dimethylbenzonitrile

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Identification
Molecular formula
C9H9NO
CAS number
33041-06-4
IUPAC name
4-hydroxy-3,5-dimethyl-benzonitrile
State
State

At room temperature, 4-hydroxy-3,5-dimethylbenzonitrile is in a solid state. It exists as a crystalline powder and is not hygroscopic, meaning it does not readily absorb moisture from the environment.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.00
Boiling point (Celsius)
325.00
Boiling point (Kelvin)
598.00
General information
Molecular weight
161.18g/mol
Molar mass
161.1840g/mol
Density
1.1250g/cm3
Appearence

4-Hydroxy-3,5-dimethylbenzonitrile appears as a light yellow crystalline solid. The crystals may vary in size and have a slight sheen, giving them a somewhat reflective surface. It is typically odorless or has a very faint aroma.

Comment on solubility

Solubility of 4-hydroxy-3,5-dimethyl-benzonitrile

4-hydroxy-3,5-dimethyl-benzonitrile, often referred to by its common name, exhibits interesting solubility characteristics that are influenced by its structural features. This compound, with its hydroxyl group and nitrile functional group, displays the following solubility properties:

  • Solvent Compatibility: It is known to be soluble in organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO). These solvents are typically polar, indicating a favorable interaction with the compound's hydroxyl group.
  • Water Solubility: While its solubility in water is limited, it can exhibit slight solubility due to hydrogen bonding capabilities brought about by the -OH group. The extent of its solubility may depend on temperature and pH.
  • Crystallization: When crystallizing from organic solvents, the purity and yield can vary significantly, highlighting the importance of selecting the right solvent for desired applications.

In summary, the solubility of 4-hydroxy-3,5-dimethyl-benzonitrile is primarily in organic solvents with some water solubility, making it essential to consider solvent choice during experimental procedures.

Interesting facts

Interesting Facts About 4-Hydroxy-3,5-dimethyl-benzonitrile

4-Hydroxy-3,5-dimethyl-benzonitrile, often referenced in the context of organic chemistry, showcases the intricate interplay between functional groups and aromatic compounds. This compound is a derivative of benzonitrile with a hydroxyl group and two methyl groups at specific positions on the benzene ring, leading to a variety of interesting properties and applications.

Key Highlights:

  • Structure: The presence of the hydroxyl (-OH) group contributes to hydrogen bonding, which can influence the compound's reactivity and interactions with other molecules.
  • Functional Groups: The combination of the nitrile (-CN) and hydroxyl groups allows for diverse chemical reactions, making this compound a versatile intermediate in organic synthesis.
  • Synthetic Pathways: This compound can be synthesized through various methods, including aromatic substitution and functional group transformations, making it a valuable substance in chemical research.
  • Applications in Research: 4-Hydroxy-3,5-dimethyl-benzonitrile is often utilized in medicinal chemistry, especially in the development of pharmaceuticals, due to its biologically significant properties.

As noted by chemists, "Understanding the structure and reactivity of compounds like 4-hydroxy-3,5-dimethyl-benzonitrile can lead to breakthroughs in drug discovery and material science." This compound exemplifies how detailed knowledge of molecular structure can lead to innovative applications in various fields.

Ultimately, the study of 4-hydroxy-3,5-dimethyl-benzonitrile not only enriches our understanding of aromatic compounds but also enhances our ability to design and synthesize new materials and medicines with tailored properties.

Synonyms
4-Hydroxy-3,5-dimethylbenzonitrile
4198-90-7
3,5-Dimethyl-4-hydroxybenzonitrile
BENZONITRILE, 3,5-DIMETHYL-4-HYDROXY-
BRN 2574734
FP7F5WF7R4
DTXSID00194791
BENZONITRILE, 4-HYDROXY-3,5-DIMETHYL-
CHEMBL-4207620
DTXCID40117282
619-915-7
2,6-Dimethyl-4-cyanophenol
4-Cyano-2,6-dimethylphenol
MFCD00221716
3,5-Dimethyl-4-hydroxybenzonitrile-d8
CHEMBL4207620
4-Hydroxy-3,5-DiMethyl-Benzonitrile
4-Hydroxy-3,5-dimethyl-benzonitrile; 2,6-Dimethyl-4-cyanophenol; 4-Cyano-2,6-dimethylphenol; 4-Hydroxy-3,5-dimethylbenzonitrile;
UNII-FP7F5WF7R4
SCHEMBL197918
CHEBI:194833
3,5,-dimethyl-4-hydroxybenzonitrile
3,5-dimethyl-4-hydroxy-benzonitrile
4-hydroxy-3,5-dimethyl benzonitrile
BDBM50458420
4-hydroxy 3, 5-dimethyl benzonitrile
AKOS005256952
AC-8502
CS-W020066
DS-0804
FD02097
PB30622
PS-4473
SB10009
AC-19781
BP-10033
SY018922
3,5-Dimethyl-4-hydroxybenzonitrile, 97%
4-Hydroxy-3,5-dimethylbenzonitrile, 98%
DB-028298
A6884
D2790
NS00077814
benzenecarbonitrile, 4-hydroxy-3,5-dimethyl-
EN300-91953