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Rimonabant

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Identification
Molecular formula
C22H21Cl3FN3O
CAS number
168273-06-1
IUPAC name
4-hydroxy-4-oxo-but-2-enoate;N-(1-methylpyrrolidin-1-ium-3-yl)-N-phenyl-acetamide
State
State

At room temperature, rimonabant is typically in a solid state, often found as a finely divided crystalline powder used in pharmaceutical formulations.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
470.00
Boiling point (Kelvin)
743.15
General information
Molecular weight
463.87g/mol
Molar mass
463.8710g/mol
Density
1.0500g/cm3
Appearence

Rimonabant is a white to off-white solid powder. It appears as crystalline particles and is often used in its hydrochloride salt form due to improved stability and solubility.

Comment on solubility

Solubility of 4-hydroxy-4-oxo-but-2-enoate; N-(1-methylpyrrolidin-1-ium-3-yl)-N-phenyl-acetamide

The solubility of the compound 4-hydroxy-4-oxo-but-2-enoate; N-(1-methylpyrrolidin-1-ium-3-yl)-N-phenyl-acetamide presents an intriguing dynamic due to its structural characteristics. The solubility can be influenced by various factors, such as:

  • Polarity: The presence of polar functional groups, such as hydroxyl and amine, increases the potential for interactions with polar solvents, particularly water.
  • Ionic Character: The ionic pyrrolidinium moiety can enhance solubility in polar environments, making it more compatible with aqueous solutions.
  • Hydrophobic Regions: The phenyl group contributes non-polar characteristics, which may create limited solubility in highly polar solvents but could enhance solubility in organic solvents.

In general, compounds similar to this one may exhibit varying levels of solubility dependent on the solvent system. For instance, as stated, "like dissolves like," meaning that polar compounds tend to be more soluble in polar solvents, while non-polar groups prefer non-polar solvents.

Consequently, it can be inferred that this compound will likely demonstrate:

  • Moderate solubility in water due to polar interactions.
  • Increased solubility in organic solvents such as ethanol or acetone.

Finally, careful consideration of the solvent environment is crucial for predicting solubility patterns, and understanding these characteristics is essential for applications in various chemical processes.

Interesting facts

Interesting Facts about 4-hydroxy-4-oxo-but-2-enoate; N-(1-methylpyrrolidin-1-ium-3-yl)-N-phenyl-acetamide

This compound, a fascinating blend of functionality and structure, deserves attention in various fields, particularly in medicinal chemistry and organic synthesis. Here are some noteworthy aspects:

  • Versatile Applications: This compound can play significant roles as a *pharmacophore*, demonstrating potential biological activities that can be leveraged in drug development.
  • Intriguing Structural Features: The presence of a pyrrolidine ring enhances the stability and reactivity of the compound, making it an interesting subject for research on *structure-activity relationships (SAR)*.
  • Biocompatibility: Its structure suggests possible compatibility with biological systems, paving the way for applications in *bioactive molecules*, as well as in materials science.
  • Innovation in Synthesis: This compound can be synthesized using various methods, providing chemists with opportunities for developing new synthetic strategies that enhance efficiency and sustainability.
  • Research Interest: As a *chiral molecule*, it may exhibit enantioselectivity, attracting interest in studies focusing on asymmetric synthesis and its influence on pharmacological behavior.

Overall, the unique combination of components in this compound highlights its potential as a novel candidate in the realms of *organic chemistry* and *pharmaceutics*. As researchers continue to explore its intricate properties, its significance in scientific advancements is poised to grow.