Ribose 5-phosphate | Solubility of Things

Identification

Molecular formula

C₅H₁₁O₈P

CAS number

4300-28-1

IUPAC name

[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl] dihydrogen phosphate

State

Ribose 5-phosphate is usually encountered in aqueous solution due to its high solubility in water. As a solid, under standard conditions, it is less commonly seen but would be considered a solid at room temperature if isolated.

Melting point (Celsius)

-1.00

Melting point (Kelvin)

-1.00

Boiling point (Celsius)

-1.00

Boiling point (Kelvin)

-1.00

General information

Molecular weight

230.11g/mol

Molar mass

230.1070g/mol

Density

1.7600g/cm³

Appearence

Ribose 5-phosphate, a carbohydrate derivative, generally does not have a well-defined appearance as it is often encountered in solution. As a pure compound, it may exist as a white to off-white crystalline powder if isolated in solid form.

Comment on solubility

Solubility of [4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl] dihydrogen phosphate

The solubility of the compound [4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl] dihydrogen phosphate (C₅H₁₁O₈P) is primarily influenced by its molecular structure, which includes functional groups that promote interactions with solvents. Here are some important aspects of its solubility:

Hydrophilicity: The presence of hydroxyl groups (-OH) in the compound increases its polarity, making it more likely to dissolve in polar solvents such as water.
Temperature Dependency: Like many organic phosphates, solubility can be temperature-dependent, often increasing with higher temperatures.
pH Sensitivity: The solubility may vary with pH changes in solution due to potential protonation or deprotonation of the phosphate group.
Concentration Effects: At higher concentrations, solubility might reach a saturation point, influencing precipitation and solubility equilibria.

In summary, the solubility characteristics of this compound are significantly defined by its functional groups and the environmental conditions in which it is placed. As the phrase goes, "like dissolves like," and in the case of [4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl] dihydrogen phosphate, its polar nature hints at a greater tendency to dissolve in compatible solvents.

Interesting facts

Interesting Facts about [4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl] dihydrogen phosphate

[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl] dihydrogen phosphate, often referred to in the context of biochemistry, is a fascinating compound that plays a crucial role in various biological processes. As a derivative of the tetrahydrofuran family, the structure comprises both hydroxyl and phosphate groups, which contribute to its reactivity and solubility in biological systems.

Key Features:

Biochemical Significance: This compound is involved in metabolic pathways and is associated with important biochemical functions, particularly in nucleic acid metabolism.
Functional Groups: The presence of multiple hydroxyl groups enhances its hydrogen bonding capability, making it more interactive in solution.
Phosphate Group: The dihydrogen phosphate moiety is crucial for energy transfer and storage in cells, as seen in ATP (adenosine triphosphate).

Furthermore, it’s noteworthy that the stereochemistry of the molecule can affect its biological activity. As highlighted by many researchers, “the spatial arrangement of atoms can significantly influence the interaction with biological targets.” This emphasizes the importance of structure in understanding the function of such compounds.

As a chemical scientist or a student, exploring the intricacies of [4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl] dihydrogen phosphate can lead to deeper insights into drug design and therapeutic applications, showcasing how a seemingly simple molecule can hold immense biological value.

Synonyms

2-deoxy-1-o-phosphonopentofuranose

[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl] dihydrogen phosphate

(4-hydroxy-5-(hydroxymethyl)oxolan-2-yl) dihydrogen phosphate

DTXSID20864747

NS00122762