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4-Hydroxybenzonitrile

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Identification
Molecular formula
C7H5NO
CAS number
767-00-0
IUPAC name
4-hydroxybenzonitrile
State
State

At room temperature, 4-Hydroxybenzonitrile is found in a solid state. It tends to remain stable and does not easily dissolve in water, which is characteristic of many organic nitrile compounds.

Melting point (Celsius)
111.00
Melting point (Kelvin)
384.15
Boiling point (Celsius)
308.00
Boiling point (Kelvin)
581.15
General information
Molecular weight
119.12g/mol
Molar mass
119.1240g/mol
Density
1.2048g/cm3
Appearence

4-Hydroxybenzonitrile, commonly known as para-hydroxybenzonitrile, appears as a white crystalline solid. Its crystalline structure gives it a distinct solid form, making it easy to handle and use in laboratory settings.

Comment on solubility

Solubility of 4-hydroxybenzonitrile

4-hydroxybenzonitrile, with the chemical formula C7H6NO, exhibits interesting solubility characteristics:

  • Polar Nature: Due to the presence of the hydroxyl (-OH) group, 4-hydroxybenzonitrile is polar, which affects its solubility in various solvents.
  • Solvent Compatibility: This compound is typically soluble in polar solvents such as:
    • Water
    • Ethanol
    • Acetone
  • Limited Solubility in Non-Polar Solvents: 4-hydroxybenzonitrile shows limited to no solubility in non-polar solvents like hexane or benzene due to its polar functional groups.
  • Temperature Dependency: With an increase in temperature, solubility in water may also enhance, showcasing typical behavior of many organic compounds.

It is essential to consider the polarity of solvents when predicting the solubility of 4-hydroxybenzonitrile, as the intermolecular forces between the compound and the solvent significantly influence solubility. As a rule of thumb, "like dissolves like," meaning polar compounds generally dissolve better in polar solvents.

Interesting facts

Interesting Facts about 4-Hydroxybenzonitrile

4-Hydroxybenzonitrile, also known as p-hydroxybenzonitrile, is an intriguing compound that finds numerous applications across different fields of chemistry and industry. Here are some captivating aspects of this compound:

  • Structural Significance: 4-Hydroxybenzonitrile is characterized by the presence of both a hydroxyl group (-OH) and a nitrile group (-CN) on a benzene ring. This unique arrangement influences its chemical reactivity and interaction with other molecules.
  • Applications in Organic Synthesis: In the realm of organic synthesis, 4-hydroxybenzonitrile serves as an important intermediate. It is often utilized in the production of various pharmaceuticals and agrochemicals, highlighting its significance in both health and agricultural sectors.
  • Role in Material Science: Interestingly, this compound is not just limited to organic synthesis; it also plays a role in material science. The compound can be used to develop specific polymers and as a building block for advanced materials.
  • Research and Development: Due to its unique properties, researchers continuously explore the potential of 4-hydroxybenzonitrile in various innovative applications, including in sensor technology and as a dye in analytical chemistry.
  • Toxicity Considerations: As with many chemical compounds, it’s essential to handle 4-hydroxybenzonitrile with care. Understanding its potential toxicological effects helps ensure safety in laboratory work and industrial applications.

In summary, 4-hydroxybenzonitrile is not merely a chemical compound; it is a versatile building block with a wide array of applications that touch many facets of modern chemistry and material science. Its continued study opens up new avenues for potential inventions and innovations in various fields.

Synonyms
4-Hydroxybenzonitrile
4-Cyanophenol
Benzonitrile, 4-hydroxy-
EINECS 212-175-2
NSC 400524
UNII-1S13529YJU
DTXSID9052509
CHEBI:38622
AI3-52392
1S13529YJU
CYANOPHENOL, P-
NSC-400524
DTXCID7031082
SR-1C14
4-HYDROXY-BENZOIC ACID,NITRILE
pCyanophenol
pHydroxybenzonitrile
4hydroxybenzonitrile
Benzonitrile, phydroxy
Benzonitrile, 4hydroxy
cvnowlnnpyyeoh-uhfffaoysa-n
inchi=1/c7h5no/c8-5-6-1-3-7(9)4-2-6/h1-4,9
767-00-0
p-Hydroxybenzonitrile
P-CYANOPHENOL
Benzonitrile, p-hydroxy-
4-CYANO PHENOL
4-Hydroxy benzonitrile
4-Hydroxybenzoic acid nitrile
4-hydroxy-benzonitrile
4-Cyanophenol--d4
MFCD00002312
4-hydroxycyanobenzene
paracyanophenol
p-cyano-phenol
4 -cyanophenol
4-cyano-phenol
4-hydroxybezonitrile
p-hydroxy-benzonitrile
p-hydroxybenzo-nitrile
p-hydroxy- benzonitrile
phenol derivative, 10
4-Cyanophenol, 95%
WLN: QR DCN
SCHEMBL50814
CHEMBL66381
benzenecarbonitrile, 4-hydroxy-
BDBM26196
BCP27582
CS-D1446
STR00817
Tox21_303855
NSC400524
STK031626
AKOS000118747
AC-2512
FC00266
PS-3371
NCGC00357121-01
CAS-767-00-0
PD182139
SY001726
NS00037833
EN300-19436
Q27117923
4-Hydroxybenzonitrile, PESTANAL(R), analytical standard
F0001-1958
Z104473840
H8N