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Bis(hydroxymethyl)cyclohexane

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Identification
Molecular formula
C8H16O2
CAS number
3409-36-9
IUPAC name
[4-(hydroxymethyl)cyclohexyl]methanol
State
State

At room temperature, bis(hydroxymethyl)cyclohexane is a solid. It remains stable in this state under standard conditions, making it useful in various applications where solid organic compounds are required.

Melting point (Celsius)
47.00
Melting point (Kelvin)
320.15
Boiling point (Celsius)
312.00
Boiling point (Kelvin)
585.15
General information
Molecular weight
144.21g/mol
Molar mass
144.2110g/mol
Density
1.0642g/cm3
Appearence

Bis(hydroxymethyl)cyclohexane is typically found as a crystalline solid. It is commonly encountered as white or colorless crystals. The crystalline nature makes it distinct in appearance compared to non-crystalline compounds.

Comment on solubility

Solubility of [4-(hydroxymethyl)cyclohexyl]methanol

[4-(hydroxymethyl)cyclohexyl]methanol is a unique compound whose solubility properties are influenced by its molecular structure. As an organic compound, it contains both hydrophilic (water-attracting) and hydrophobic (water-repelling) portions, which can significantly affect its solubility in various solvents.

Solubility Characteristics

The solubility of [4-(hydroxymethyl)cyclohexyl]methanol can be summarized as follows:

  • Polar solvents: The presence of the hydroxymethyl group enhances solubility in polar solvents such as water, due to hydrogen bonding capabilities.
  • Non-polar solvents: Due to the cyclohexyl portion of the molecule, it may exhibit limited solubility in non-polar solvents like hexane or benzene.
  • Alcohols and ethers: Solubility is generally expected to be good in alcohols and ethers due to similar polar characteristics.

In summary, while [4-(hydroxymethyl)cyclohexyl]methanol shows promising solubility in polar solvents, it may face challenges in non-polar environments. The compound exemplifies how molecular structure profoundly impacts solubility behavior.

Interesting facts

Interesting Facts about [4-(hydroxymethyl)cyclohexyl]methanol

[4-(hydroxymethyl)cyclohexyl]methanol is a fascinating compound with significant implications in various fields, particularly in organic chemistry and material science. Here are some intriguing aspects of this compound:

  • Structure and Functionality: The compound contains a cyclohexyl ring, which contributes to its unique chemical properties. The presence of hydroxymethyl groups significantly enhances its reactivity and influences its interactions with other molecules.
  • Applications: This compound is not just of theoretical interest; it finds applications in:
    • Pharmaceuticals: Used in the synthesis of active pharmaceutical ingredients due to its versatile functional groups.
    • Polymer Chemistry: Acts as a building block for creating innovative materials with enhanced properties, such as flexibility and strength.
  • Biological Relevance: The structural resemblance of [4-(hydroxymethyl)cyclohexyl]methanol to various natural compounds suggests its potential roles in biological systems. Researchers are investigating its anti-inflammatory and antioxidant properties.
  • Synthetic Pathways: The synthesis of this compound illustrates important techniques in organic chemistry, involving methods such as:
    • Nucleophilic substitutions.
    • Reduction reactions.
  • Research Potential: Due to its unique characteristics, [4-(hydroxymethyl)cyclohexyl]methanol is a compound of interest in ongoing research in the fields of:
    • Drug Design: Understanding the interactions and potential therapeutic effects.
    • Material Science: Developing new materials with specific desirable properties.

In conclusion, [4-(hydroxymethyl)cyclohexyl]methanol exemplifies how a single compound can bridge multiple disciplines, offering exciting opportunities for both theoretical exploration and practical applications.

Synonyms
1,4-CYCLOHEXANEDIMETHANOL
trans-1,4-Cyclohexanedimethanol
3236-48-4
105-08-8
CHDM
[4-(hydroxymethyl)cyclohexyl]methanol
3236-47-3
1,4-Bis(hydroxymethyl)cyclohexane
cis-1,4-Cyclohexanedimethanol
1,4-Chidm
cyclohexanedimethanol
Rikabinol DM
Cyclohexane-1,4-dimethanol
1,4-Cyclohexanedimethanol, cis-
1,4-Dimethylolcyclohexane
1,4-Cyclohexanedimethanol, trans-
trans-cyclohexane-1,4-diyldimethanol
Cyclohex-1,4-ylenedimethanol
HSDB 5364
trans-1,4-Bis(hydroxymethyl)cyclohexane
1,4-Cyclohexamethylenebis methylol
cis-cyclohexane-1,4-diyldimethanol
UNII-8C3FKR6R1B
EINECS 203-268-9
NSC 44508
BRN 1902271
DTXSID9026712
AI3-28853
MFCD00066360
EC-No. 203-268-9
8C3FKR6R1B
(trans-4-Hydroxymethylcyclohexyl)methanol
cis-[4-(hydroxymethyl)cyclohexyl]methanol
cyclohexane-1,4-diyldimethanol
trans-(4-hydroxymethyl-cyclohexyl)-methanol
DTXCID106712
[(1r,4r)-4-(hydroxymethyl)cyclohexyl]methanol
EC 203-268-9
47A69Y3G5M
MFCD00064957
NSC-44508
cis-1,4-bis(hydroxymethyl)cyclohexane
7I8476P8P0
cis-(cyclohexane-1,4-diyl)dimethanol
PM 1597
cis-CHDM
Sky CHDM
Vibracure A 240
CHDM-D
MFCD00001512
1,4-cyclohexane dimethanol
UNII-47A69Y3G5M
UNII-7I8476P8P0
(trans-4-Hydroxymethylcyclohexyl)methanol; trans-1,4-Bis(hydroxymethyl)cyclohexane;
trans-CHDM
1,4-Cyclohexanedimethanol, (Z)-
CHDM, trans isomer
CHDM, cis
AI3-26300
1,4 cyclohexanedimethanol
1,4 cyclohexane dimethanol
1,4-cyclo-hexanedimethanol
1,4-cyclohexane-dimethanol
SCHEMBL27912
SCHEMBL130642
SCHEMBL297828
1,4-dihydroxymethylcyclohexane
1,4-Cyclohexanedimethanol,c&t
WLN: L6TJ A1Q D1Q
(Z)-1,4-cyclohexanedimethanol
1,4-Cyclohexanedimethanol, cis
CHEMBL3185118
Cyclohexane-1,4-dimethanol,c&t
SCHEMBL13461142
1,4-CYCLOHEXADIMETHANOL-
1,4-Cyclohexanedimethanol, trans
DTXSID00274143
DTXSID60274144
trans-1,4-cyclohexane dimethanol
trans-cyclohexane-1,4-dimethanol
(4-Hydroxymethylcyclohexyl)methanol
NSC44508
Tox21_200433
trans-1,4-dihydroxymethylcyclohexane
1,4-bis-(hydroxymethyl)-cyclohexane
AC-291
Cyclohex-1,4-ylenedimethanol, trans
AKOS009031609
AKOS015833096
AKOS028109404
1,4-Bis(hydroxymethyl)cyclohexane,c&t
AT36023
CS-W016379
EAN 087583
EASTMAN VERITYL AB-1000 DIOL
SB17942
1,4-Cyclohexanedimethanol, cis + trans
(1r,4r)-cyclohexane-1,4-diyldimethanol
NCGC00248612-01
NCGC00257987-01
AS-18294
CAS-105-08-8
SY024459
SY342154
DB-026925
C2234
NS00007618
EN300-19999
alpha,alpha'-Dihydroxy-1,4-dimethylcyclohexane
F87287
EN300-1721997
Q1064929
1,4-Cyclohexanedimethanol, mixture of (cis) and trans
Q27259032
Q27268338
Z104476328
1,4-Cyclohexanedimethanol, trans- (70%) and cis- (30%)
203-268-9