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4-hydroxypentan-2-one

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Identification
Molecular formula
C5H10O2
CAS number
123-76-2
IUPAC name
4-hydroxypentan-2-one
State
State

At room temperature, 4-Hydroxypentan-2-one is typically a liquid.

Melting point (Celsius)
-44.00
Melting point (Kelvin)
229.15
Boiling point (Celsius)
144.00
Boiling point (Kelvin)
417.15
General information
Molecular weight
102.13g/mol
Molar mass
102.1310g/mol
Density
0.9755g/cm3
Appearence

4-Hydroxypentan-2-one is a colorless liquid, and it possesses a distinctive sweet, berry-like odor. It is often used in flavors, fragrances, and as a building block in chemical synthesis due to its reactivity.

Comment on solubility

Solubility of 4-hydroxypentan-2-one

4-hydroxypentan-2-one, also known as acetyl-1,2-propanediol, exhibits interesting solubility characteristics that are quite significant in various applications. Its polar hydroxyl groups contribute to its ability to interact with water molecules.

Key Points on Solubility:

  • Water Solubility: 4-hydroxypentan-2-one is generally soluble in water, primarily due to the presence of the hydroxyl group (–OH), which facilitates hydrogen bonding with water.
  • Organic Solvents: This compound is also soluble in many organic solvents such as ethanol and ethyl acetate. This property makes it useful in organic reactions and formulations.
  • Temperature Effects: As temperature increases, the solubility of 4-hydroxypentan-2-one in both water and organic solvents can enhance, illustrating typical solvent behavior.

Moreover, the solubility of a compound like 4-hydroxypentan-2-one can vary with the presence of impurities or the method of preparation. As stated, "solubility is a complex interplay of molecular interactions." Therefore, in practical applications, it is often beneficial to conduct empirical solubility tests to determine the behavior of this compound under specific conditions.

Understanding the solubility profile of 4-hydroxypentan-2-one is essential for researchers and professionals working with this compound, as it directly influences its reactivity, behavior in mixtures, and effectiveness in different industrial applications.

Interesting facts

Interesting Facts About 4-Hydroxypentan-2-one

4-Hydroxypentan-2-one is a fascinating organic compound, primarily known as an intermediate in various chemical syntheses. This compound plays a role in the production of numerous pharmaceuticals and agrochemicals, making it significant in both industrial and research settings.

Key Features:

  • Functional Groups: The presence of both a hydroxyl (–OH) and a ketone (C=O) group in its structure enables 4-hydroxypentan-2-one to exhibit unique reactivity. This dual functionality allows for a variety of chemical reactions, including condensation and oxidation.
  • Synthesis: The compound can be synthesized through several methods, one of which is the reduction of 4-oxopentan-2-one, showcasing the versatility of organic reactions.
  • Applications: It's notably used in the manufacture of flavoring agents and solvents, adding to its versatility in various applications beyond pharmaceuticals.
  • Biological Relevance: This compound has also sparked interest in biochemistry, as it is involved in metabolic pathways, making it a subject of study in understanding metabolic disorders.

The compound's structural complexity allows chemists to explore various reaction pathways, often resulting in derivatives with intriguing biological activities. As noted by researchers, "the exploration of hydroxylated ketones like 4-hydroxypentan-2-one can lead to the discovery of new therapeutic agents.”

Overall, the significance of 4-hydroxypentan-2-one in both industrial and scientific communities highlights the importance of understanding chemical compounds in advancing research and technology.

Synonyms
4-Hydroxypentan-2-one
4-HYDROXY-2-PENTANONE
EINECS 224-003-3
DTXSID70864393
NSC 263780
DTXCID30812916
224-003-3
4161-60-8
2-Pentanone, 4-hydroxy-
CH3CH(OH)CH2C(O)CH3
(4S)-4-Hydroxypentan-2-one
(4R)-4-HYDROXYPENTAN-2-ONE
63315-69-5
NSC263780
4-Hydroxy-2-pentanone #
SCHEMBL153744
2-PENTANONE-4-HYDROXY
4-Hydroxy-4-methyl-2-butanone
AKOS014026559
NSC-263780
DS-015160
NS00048427
EN300-243210
F87631