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Edaravone

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Identification
Molecular formula
C11H12IN2O
CAS number
89-25-8
IUPAC name
4-iodo-1,5-dimethyl-2-phenyl-pyrazol-3-one
State
State

At room temperature, Edaravone is in a solid state.

Melting point (Celsius)
129.00
Melting point (Kelvin)
402.15
Boiling point (Celsius)
433.50
Boiling point (Kelvin)
706.70
General information
Molecular weight
256.13g/mol
Molar mass
256.0970g/mol
Density
1.4940g/cm3
Appearence

Edaravone appears as a white to slightly yellowish crystalline powder.

Comment on solubility

Solubility of 4-iodo-1,5-dimethyl-2-phenyl-pyrazol-3-one

The solubility of 4-iodo-1,5-dimethyl-2-phenyl-pyrazol-3-one can be influenced by a variety of factors including polarity, the presence of functional groups, and the overall molecular structure. Here are some key points to consider:

  • Polar versus Non-Polar: The molecule features a halogen (iodine) and aromatic groups which can affect its polarity. This can lead to differences in solubility depending on the solvent used.
  • Solvent Compatibility: Typically, compounds with similar functional groups tend to dissolve well in solvents with matching polarities. 4-iodo-1,5-dimethyl-2-phenyl-pyrazol-3-one may be more soluble in polar organic solvents like methanol or ethanol due to its overall structure.
  • Temperature Influence: Increasing the temperature can enhance the solubility of many organic compounds, including this one. As you raise the temperature, kinetic energy increases and can help overcome intermolecular attractions.
  • Hydrogen Bonding: If the compound can form hydrogen bonds, it may demonstrate increased solubility in certain solvents where such interactions are favorable.

Despite these factors, specific solubility data for 4-iodo-1,5-dimethyl-2-phenyl-pyrazol-3-one is limited, making it essential to conduct further experiments for accurate solubility characterization.

Interesting facts

Interesting Facts about 4-Iodo-1,5-Dimethyl-2-Phenyl-Pyrazol-3-One

4-Iodo-1,5-dimethyl-2-phenyl-pyrazol-3-one is a fascinating compound that belongs to the pyrazolone class of compounds, renowned for their diverse applications in various fields of research and industry. Here are some intriguing aspects of this chemical:

  • Structural Diversity: The presence of the iodo group and multiple methyl groups contributes to the compound's unique structural characteristics, enhancing its reactivity.
  • Pharmacological Potential: Similar compounds have been studied for their potential as anti-inflammatory, analgesic, and antipyretic agents. The presence of the phenyl group may also suggest interesting biological activities.
  • Synthesis: The synthesis of pyrazolone derivatives often involves versatile methods, including cyclization and substitution reactions. This compound can be synthesized using a variety of approaches, showcasing the creativity and flexibility in organic synthesis.
  • Applications in Materials Science: Compounds like this one may have applications in developing new materials with specific electronic or optical characteristics, owing to their unique electronic properties.
  • Analytical Chemistry: 4-Iodo-1,5-dimethyl-2-phenyl-pyrazol-3-one can serve as a key intermediate in synthesizing other complex molecules, making it valuable in analytical chemistry and synthetic organic chemistry.

As a student or researcher, understanding the potential uses and properties of compounds like 4-iodo-1,5-dimethyl-2-phenyl-pyrazol-3-one opens up numerous avenues for exploration. Intriguingly, the study of such compounds can also lead to the discovery of new therapeutic agents or advanced materials, emphasizing the importance of this class of chemicals in modern chemistry.

Synonyms
IODOANTIPYRINE
129-81-7
4-Iodoantipyrine
Iodopyrine
Antipyrine iodide
Iodophenazone
Jodantipyrine
Arthripur
Jodopyrine
3H-Pyrazol-3-one, 1,2-dihydro-4-iodo-1,5-dimethyl-2-phenyl-
Antipyrine, 4-iodo-
EINECS 204-966-6
4-Iodo-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one
UNII-V30V6H1QX4
V30V6H1QX4
4-Iodo-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
DTXSID7046047
4-iodo-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
IODOPHENAZONE [WHO-DD]
4-iodo-1,5-dimethyl-2-phenylpyrazol-3-one
DTXCID5026047
1,2-Dihydro-4-iodo-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
4-Iod-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on
NCGC00159397-02
NCGC00159397-03
1,2-Dihydro-4-iod-1,5-dimethyl-2-phenyl-3H-pyrazol-3-on
1,2-Dihydro-4-iodo-1,5-dimethyl-2-phenyl-2H-pyrazol-3-one
1,2-Dihydro-4-iod-1,5-dimethyl-2-phenyl-3H-pyrazol-3-on [IUPAC]
CAS-129-81-7
1,2-Dihydro-4-iod-1,5-dimethyl-2-phenyl-3H-pyrazol-3-on (IUPAC)
MFCD00040720
CHEMBL24132
SCHEMBL1148899
1,5-Dimethyl-4-iodo-2-phenyl-1,2-dihydro-pyrazol-3-one
Tox21_111636
STL577304
AKOS005207004
Tox21_111636_1
AC-5017
Antipyrine, 4-iodo-(6CI,7CI,8CI)
FI65044
BS-52922
HY-116070
CS-0063717
NS00001101
E75849
SBI-0653880.0001
AN-584/43522517
SR-01000945033
1-Phenyl-2,3-dimethyltetrahydropyrazole hydroiodide
Q4205877
SR-01000945033-1
BRD-K69216798-001-01-9
3H-Pyrazol-3-one,1,2-dihydro-4-iodo-1,5-dimethyl-2-phenyl-
pyrazole, 2,3-dihydro-4-iodo-1,5-dimethyl-3-oxo-2-phenyl-
204-966-6