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Menthol

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Identification
Molecular formula
C10H20O
CAS number
89-78-1
IUPAC name
4-isopropyl-1-methyl-cyclohex-3-en-1-ol
State
State

At room temperature, menthol is in a solid crystalline state. It is often used in medicated creams, ointments, and cooling gels.

Melting point (Celsius)
42.00
Melting point (Kelvin)
315.15
Boiling point (Celsius)
212.00
Boiling point (Kelvin)
485.15
General information
Molecular weight
156.27g/mol
Molar mass
156.2690g/mol
Density
0.8906g/cm3
Appearence

Menthol is typically a white crystalline substance, existing as small needle-like crystals or as granular powder. It is solid at room temperature. Menthol has a characteristic strong, minty odor and a cooling sensation when applied to skin or mucous membranes.

Comment on solubility

Solubility of 4-isopropyl-1-methyl-cyclohex-3-en-1-ol

The solubility of 4-isopropyl-1-methyl-cyclohex-3-en-1-ol in various solvents can present interesting behavioral characteristics due to its molecular structure. This compound, being an alcohol, typically exhibits the following solubility traits:

  • Polar Solvents: 4-isopropyl-1-methyl-cyclohex-3-en-1-ol is likely to be soluble in polar solvents such as water or alcohols due to the presence of the hydroxyl (-OH) group, which can form hydrogen bonds.
  • Non-Polar Solvents: The hydrocarbon portion of the molecule may lead to some degree of solubility in non-polar solvents like hexane or benzene, although generally to a lesser extent than in polar solvents.
  • Temperature Influence: Solubility can also be affected by temperature, as increasing the temperature may enhance the solubility of this compound in various solvents.

It is important to note that the overall solubility is contingent upon the specific conditions and the chemical environment surrounding the compound. As a general observation, alcohols tend to have better solubility in water compared to their non-alcohol counterparts:

  1. Structure-Activity Relationship: The presence of bulky isopropyl and methyl groups can hinder compact packing and might affect solubility.
  2. Functional Group Interaction: The hydroxyl group enhances hydrogen bonding with water molecules, boosting aqueous solubility.

Thus, understanding the solubility of 4-isopropyl-1-methyl-cyclohex-3-en-1-ol requires consideration of both the polar and non-polar aspects of the molecule, which dictate its behavior in different solvent environments.

Interesting facts

Interesting Facts about 4-Isopropyl-1-methyl-cyclohex-3-en-1-ol

4-Isopropyl-1-methyl-cyclohex-3-en-1-ol is a fascinating organic compound that belongs to the class of alcohols, distinguished by its unique structure and properties. Here are some intriguing aspects of this compound:

  • Structural Complexity: This compound features a cyclohexene ring, which adds a layer of stability and reactivity. The presence of the isopropyl and methyl groups not only influences its physical properties but also its reactivity in chemical reactions.
  • Functional Versatility: As an alcohol, 4-isopropyl-1-methyl-cyclohex-3-en-1-ol can serve as a valuable intermediate in organic synthesis, allowing chemists to create a variety of derivatives that may possess desirable biological activities.
  • Taste and Aroma: Compounds with similar structural motifs often exhibit interesting aromatic profiles. While the specific sensory characteristics of 4-isopropyl-1-methyl-cyclohex-3-en-1-ol might require further study, many alcohols play essential roles in flavor and fragrance industries.
  • Potential Biological Activity: Some studies suggest that alcohols with complex cyclic structures may possess antimicrobial or anti-inflammatory properties, making them of interest in pharmaceutical development.
  • Synthetic Pathways: The synthesis of this compound can involve diverse methods, such as cyclization reactions or functional group transformations, making it an exciting target for organic chemists seeking to expand their repertoire of synthetic techniques.

In summary, 4-isopropyl-1-methyl-cyclohex-3-en-1-ol stands as a *captivating example* of how the intricate design of molecular structures can lead to a wealth of possibilities in both chemical synthesis and applications. Its multifaceted nature serves to inspire both students and practitioners in the field of chemistry.

Synonyms
p-Menth-3-en-1-ol
586-82-3
1-Terpineol
1-Terpinenol
3-Terpinen-1-ol
3-Cyclohexen-1-ol, 1-methyl-4-(1-methylethyl)-
4-(Isopropyl)-1-methylcyclohex-3-en-1-ol
para-menth-3-en-1-ol
1-methyl-4-propan-2-ylcyclohex-3-en-1-ol
FEMA No. 3563
Terpinen-1-ol
E09RQ2NK3G
1-Methyl-4-isopropyl-3-cyclohexen-1-ol
4-Isopropyl-1-methyl-3-cyclohexen-1-ol
EINECS 209-585-9
1-METHYL-4-(1-METHYLETHYL)-3-CYCLOHEXEN-1-OL
DTXSID40862245
3-Cyclohexen-1-ol, 1-methyl-4-(1-methyethyl)-
P-MENTH-3-EN-1-OL [FHFI]
1-METHYL-4-ISOPROPYLCYCLOHEX-3-ENOL
DTXCID20811039
(+-)-p-menth-3-en-1-ol
p-menth-3-en-1-ol, (+-)-
xi-p-Menth-3-en-1-ol
(+/-)-P-MENTH-3-EN-1-OL
P-MENTH-3-EN-1-OL, (+/-)-
1-methyl-4-(propan-2-yl)cyclohex-3-en-1-ol
UNII-E09RQ2NK3G
Terpineol-1
Terpin-3-en-1-ol
4-isopropyl-1-methyl-cyclohex-3-en-1-ol
SCHEMBL1245680
4-Isopropyl-1-methyl-3-cyclohexen-1-ol #
DB-282925
NS00043058
EN300-6773342
Q27276701