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p-Cresol

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Identification
Molecular formula
C9H12O
CAS number
99-89-8
IUPAC name
4-isopropylphenol
State
State

Under standard conditions, 4-isopropylphenol is a solid. It has a typical melting point of around 61°C which means it is usually found in solid state at room temperature.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
238.00
Boiling point (Kelvin)
511.15
General information
Molecular weight
136.21g/mol
Molar mass
136.2060g/mol
Density
0.9640g/cm3
Appearence

4-Isopropylphenol, also known as p-isopropylphenol, typically appears as white crystalline solid flakes or powder. It can also appear as colorless crystals. This compound is known for its phenolic odor, which is quite pungent and medicinal.

Comment on solubility

Solubility of 4-Isopropylphenol

4-Isopropylphenol, with the chemical formula C10H14O, presents certain characteristics that affect its solubility in various solvents.

General Solubility Characteristics

This compound exhibits interesting solubility properties, which can be summarized as follows:

  • Solvent Dependence: 4-Isopropylphenol is primarily soluble in organic solvents such as ethanol and acetone.
  • Water Solubility: It has limited solubility in water, mainly due to its hydrophobic hydrocarbon structure.
  • Temperature Effect: Solubility often increases with temperature; therefore, it may become more soluble in hot solvents.

Moreover, the hydroxyl group (-OH) present in its structure contributes to the creation of hydrogen bonds with polar solvents, enhancing solubility to a certain extent. However, the presence of the isopropyl group introduces a degree of hydrophobicity, which can restrict full solubility in water.

In summary, the solubility of 4-isopropylphenol in various solvents can significantly impact its use in practical applications, requiring careful consideration of solvent choice based on its solubility profile.

Interesting facts

Interesting Facts About 4-Isopropylphenol

4-Isopropylphenol, also known as p-cresol, is a fascinating compound that belongs to the family of phenolic compounds. Here are some of the intriguing aspects of this compound:

  • Structure and Isomerism: The unique structure of 4-isopropylphenol features an isopropyl group attached to the phenolic ring, allowing it to exist in a specific orientation or isomer. This isomeric arrangement is crucial in determining its reactivity and interactions with other substances.
  • Biological Significance: 4-Isopropylphenol exhibits antibacterial properties, making it important in various applications, particularly in the medical and health fields. It can help in inhibiting the growth of certain bacteria, thus playing a role in disinfection.
  • Industrial Applications: This compound is utilized in the synthesis of various chemical compounds, including pharmaceuticals and agrochemicals. Its versatility in the chemical industry marks it as an essential building block for more complex molecules.
  • Environmental Impact: As with many chemical compounds, understanding the environmental footprint of 4-isopropylphenol is critical. Research continues to explore its biodegradability and potential toxicity to ecosystems, ensuring that safe practices are observed in its use.
  • Flavor and Fragrance: Interestingly, 4-isopropylphenol contributes to the aroma of certain plant species. This characteristic can be harnessed in the flavor and fragrance industry, enhancing the sensory experience of various products.

The study of 4-isopropylphenol not only showcases the complexity of chemical compounds but also emphasizes the importance of chemical safety and environmental considerations in modern science.

Synonyms
4-Isopropylphenol
99-89-8
P-ISOPROPYLPHENOL
p-Cumenol
Australol
4-(1-Methylethyl)phenol
Phenol, 4-(1-methylethyl)-
1-Hydroxy-4-isopropylbenzene
4-(Propan-2-Yl)Phenol
4-propan-2-ylphenol
para-isopropylphenol
4-Hydroxycumene
Phenol, p-isopropyl-
Prodox 133
4-iso-Propylphenol
4-Isopropyl phenol
4-Isopropyl-phenol
NSC 1888
p-hydroxycumene
p-ISOPROPYL PHENOL
EINECS 202-798-8
BRN 1363564
DTXSID5042299
9F59JOO816
NSC-1888
MFCD00002372
ISOPROPYLPHENOL, P-
Phenol, (1-methylethyl)-
DTXCID3022299
CHEBI:167172
4-06-00-03215 (Beilstein Handbook Reference)
PROPOFOL IMPURITY H [EP IMPURITY]
P-Cuminol
PROPOFOL IMPURITY H (EP IMPURITY)
pCumenol
pIsopropylphenol
UNII-9F59JOO816
4-(1-Methylethyl)phenol; Propofol Imp. H (EP); Propofol Impurity H
paraisopropylphenol
Phenol, pisopropyl
phenol, 4-isopropyl-
4(1Methylethyl)phenol
1Hydroxy4isopropylbenzene
Phenol, 4(1methylethyl)
4-Isopropylphenol, 98%
SCHEMBL28954
CHEMBL29966
SCHEMBL8987962
WLN: QR DY1 & 1
NSC1888
HMS1789L08
STR08167
Tox21_301323
STL183327
AKOS000121483
CAS-99-89-8
NCGC00255837-01
NCGC00337683-01
PD065569
CS-0020286
I0262
NS00012766
EN300-16601
D72532
AB01329173-02
AE-562/43459027
Q27272471
Z56347200
F0001-2340
202-798-8
H3Z