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TFMPP

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Identification
Molecular formula
C21H26N2O4
CAS number
15532-75-9
IUPAC name
[4-(m-tolylmethyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone
State
State

At room temperature, TFMPP is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
127.00
Melting point (Kelvin)
400.00
Boiling point (Celsius)
412.85
Boiling point (Kelvin)
686.00
General information
Molecular weight
326.40g/mol
Molar mass
326.4010g/mol
Density
1.2090g/cm3
Appearence

TFMPP appears as a white or off-white crystalline powder. It is typically fine and smooth in texture, resembling many other crystalline powders used in chemical applications.

Comment on solubility

Solubility Characteristics of [4-(m-tolylmethyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone

The solubility of [4-(m-tolylmethyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone can be influenced by several factors, including its molecular structure and interactions with solvents. Here are some important considerations:

  • Polarity: The presence of multiple methoxy groups (–OCH3) in the chemical structure contributes to a relatively moderate polarity, which can enhance solubility in polar solvents.
  • Solvent Compatibility: This compound is likely to show good solubility in polar organic solvents such as ethanol and methanol, while being less soluble in nonpolar solvents.
  • Hydrogen Bonding: The piperazine ring may also create opportunities for hydrogen bonding with polar solvents, further influencing solubility.
  • Temperature Effects: Generally, an increase in temperature may enhance solubility due to increased molecular motion, but this can vary based on the specific characteristics of the compound.
  • pH Sensitivity: If the compound exists as an ionizable species, its solubility could change significantly with pH shifts in solution, making it essential to consider the environmental conditions.

In conclusion, the solubility of [4-(m-tolylmethyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone is complex and context-dependent, underscoring the importance of selecting appropriate solvents and conditions when working with this compound.

Interesting facts

Interesting Facts About [4-(m-tolylmethyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone

This compound is a fascinating example of a synthetic organic molecule that combines the structural features of piperazines and methoxy-substituted phenyl rings. Let's explore some intriguing aspects of this compound that highlight its significance in the field of chemistry:

  • Pharmaceutical Potential: The unique structure of this compound suggests potential applications in medicinal chemistry, particularly as a pharmacophore for drug development. Its complex molecular architecture may interact with various biological targets, offering avenues for therapeutic interventions.
  • Diverse Functional Groups: This compound possesses multiple functional groups, including the piperazine ring and methoxy groups. These features can significantly influence the compound's reactivity and molecular interactions, making it a prime candidate for further studies.
  • Biological Activity: Compounds incorporating piperazine and methoxyphenyl fragments often show interesting biological activities, such as anti-depressant and anti-anxiety effects. This suggests that this compound may also exhibit similar properties, warranting investigation into its biological efficacy.
  • Synthesis Challenges: The synthesis of such compounds may present challenges, as the introduction of multiple substituents onto the phenyl ring requires careful control of reaction conditions. This complexity can lead to diverse reaction pathways and by-products, making the synthesis an intriguing topic for organic chemists.
  • Research Opportunities: The compound serves as a valuable template for chemists looking to explore structure-activity relationships. By modifying the substituents on the piperazine or phenyl ring, researchers can tailor the compound's properties for specific applications.

In summation, [4-(m-tolylmethyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone is a compound ripe for exploration. Its intriguing structure and potential applications in pharmaceuticals make it a worthwhile subject of study for both seasoned chemists and enthusiastic students.

Synonyms
Oprea1_112442
Oprea1_825832
AKOS000553593
1-[(3-METHYLPHENYL)METHYL]-4-(3,4,5-TRIMETHOXYBENZOYL)PIPERAZINE