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4-Methoxy-1,3-benzothiazol-2-amine

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Identification
Molecular formula
C8H8N2OS
CAS number
97528-45-1
IUPAC name
4-methoxy-1,3-benzothiazol-2-amine
State
State

At room temperature, 4-Methoxy-1,3-benzothiazol-2-amine is typically in a solid state. It is not very volatile and remains stable as a solid under normal laboratory conditions.

Melting point (Celsius)
146.00
Melting point (Kelvin)
419.20
Boiling point (Celsius)
332.50
Boiling point (Kelvin)
605.60
General information
Molecular weight
180.24g/mol
Molar mass
180.2360g/mol
Density
1.4301g/cm3
Appearence

This compound appears as a pale yellow to white crystalline powder. The crystals can be needle-like and can be observed under a microscope. The intensity of the yellow hue may vary based on purity and specific conditions.

Comment on solubility

Solubility of 4-methoxy-1,3-benzothiazol-2-amine

The solubility of 4-methoxy-1,3-benzothiazol-2-amine can vary significantly depending on the solvent and environmental conditions. Understanding its solubility is crucial for applications in pharmaceuticals and biochemical research. Here are some key points regarding its solubility:

  • Polar Solvents: This compound tends to exhibit better solubility in polar solvents such as water and alcohols due to the presence of the amine functional group, which can engage in hydrogen bonding.
  • Non-polar Solvents: Its solubility in non-polar solvents is considerably lower, reflecting the hydrophobic character of the benzothiazole ring.
  • Solubility Product: The Ksp of 4-methoxy-1,3-benzothiazol-2-amine is often an important parameter in determining its solubility under various conditions.
  • Temperature Dependence: Increased temperature may enhance solubility in certain solvents, making it essential to consider the thermal conditions during experiments.

It can be summarized that 4-methoxy-1,3-benzothiazol-2-amine is generally more soluble in polar environments, with solubility characteristics that are influenced by various factors including temperature and the solvent type. Understanding these properties is vital for optimizing its use in different chemical applications.

Interesting facts

Interesting Facts about 4-methoxy-1,3-benzothiazol-2-amine

4-methoxy-1,3-benzothiazol-2-amine is a fascinating compound that belongs to the benzothiazole family, which is known for its wide range of biological activities and applications in various fields. Here are some remarkable aspects of this compound:

  • Biological Significance: Compounds with the benzothiazole structure often exhibit antimicrobial, antifungal, and anticancer activities, making them valuable in pharmaceutical research. Studies have highlighted the potential of 4-methoxy-1,3-benzothiazol-2-amine in drug development.
  • Versatile Applications: Due to its unique chemical properties, this compound is explored for diverse applications, including use as a dye, in agrochemicals, and as a corrosion inhibitor. Its applications are pivotal in materials science and environmental chemistry.
  • Synthetic Pathways: The synthesis of 4-methoxy-1,3-benzothiazol-2-amine can be achieved through several methods, often involving the reaction of specific amines with benzothiazole derivatives. This versatility allows chemists to tailor the synthesis to suit specific research needs.
  • Research Opportunities: There is ongoing research into the mechanism of action and biological pathways influenced by this compound. Understanding these pathways could open up new avenues for treating diseases and enhancing agricultural practices.
  • Environmental Consideration: As a compound that can be involved in various chemical reactions, it is essential to study its environmental impact, persistence, and degradation pathways to ensure safety in its applications.

Overall, 4-methoxy-1,3-benzothiazol-2-amine represents an intersection of chemistry, biology, and environmental science, making its study worthwhile for those interested in the myriad manifestations of chemical compounds in the natural and synthetic worlds.

Synonyms
2-AMINO-4-METHOXYBENZOTHIAZOLE
5464-79-9
4-Methoxy-2-aminobenzothiazole
2-Benzothiazolamine, 4-methoxy-
Benzothiazole, 2-amino-4-methoxy-
4-Methoxybenzothiazol-2-ylamine
EINECS 226-763-1
NSC 28740
BRN 0141363
DTXSID4024484
NSC-28740
7E3D8644F2
DTXCID204484
4-27-00-05446 (Beilstein Handbook Reference)
4-METHOXY-2-BENZOTHIAZOLAMINE
AMINO-4-METHOXYBENZOTHIAZOLE, 2-
(4-METHOXYBENZOTHIAZOL-2-YL)AMINE
BENZOTHIAZOLE, 1-AMINO-3-METHOXY-
2-Benzothiazolamine, 4-methoxy-(9CI)
4-methoxy-1,3-benzothiazol-2-amine
4-methoxybenzo[d]thiazol-2-amine
2-Amino-4-methoxy-benzothiazole
4-Methoxy-benzothiazol-2-ylamine
MFCD00005792
UNII-7E3D8644F2
4-Methoxybenzothiazole-2-ylamine
NSC28740
2-Amino-methoxybenzothiazole
Oprea1_723719
MLS002152866
2-Amino-4-methoxybenzothiazol
BIDD:GT0141
SCHEMBL624781
methoxybenzo[d]thiazol-2-amine
IFLab1_006388
2-amino 4-methoxy benzothiazole
CHEMBL1487454
HMS1430D07
HMS3039I11
STR07534
WLN: T56 BN DSJ CZ IO1
Tox21_200251
2-amino-4-methoxy-1,3-benzothiazole
2-Amino-4-methoxybenzothiazole, 96%
AKOS000274148
FS-2258
SB18598
NCGC00091406-01
NCGC00091406-02
NCGC00257805-01
4-Methoxy-1,3-benzothiazol-2-ylamine #
AC-31697
SMR001224486
SY031704
CAS-5464-79-9
DB-020437
DB-349477
A2454
CS-0054537
NS00033157
EN300-02268
A14014
SR-01000390818
SR-01000390818-1
Q27268135
F1911-0005
Z104442614
InChI=1/C8H8N2OS/c1-11-5-3-2-4-6-7(5)10-8(9)12-6/h2-4H,1H3,(H2,9,10