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Berberine chloride

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Identification
Molecular formula
C20H18ClNO4
CAS number
633-65-8
IUPAC name
4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride
State
State

Berberine chloride is solid at room temperature. It is commonly available in fine, crystalline powder form, which can disperse into the air if not handled carefully. When not in powder form, it can also be found in crystalline structures.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
518.30
Boiling point (Kelvin)
791.30
General information
Molecular weight
368.82g/mol
Molar mass
368.8200g/mol
Density
1.3006g/cm3
Appearence

Berberine chloride is a yellow crystalline solid. It is frequently encountered in powder form, exhibiting a yellow hue that can vary in intensity depending on its purity and concentration. This compound is known for its bright yellow color, which makes it easy to identify.

Comment on solubility

Solubility of 4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium Chloride

The solubility characteristics of 4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium chloride play a critical role in its application across various scientific fields. Understanding its solubility can be broken down into several key aspects:

  • Solvent Compatibility: This compound is generally soluble in polar solvents due to the presence of the ionic Cl- component, which enhances its dissolution capabilities in aqueous solutions.
  • Temperature Dependence: Like many ionic compounds, solubility can increase with temperature. Thus, higher temperatures can lead to greater solubility, which is essential for practical applications that involve esterification or preparations in varied thermal conditions.
  • pH Influence: An acidic environment may further enhance its solubility, a trait useful in formulations where pH adjustments are feasible.

In summary, the solubility of 4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium chloride is significantly influenced by the polar nature of its ionic component, temperature, and pH of the solvent. This makes it a compound of interest for both laboratory and industrial settings, highlighting the necessity of careful consideration of solubility in practical applications.

Interesting facts

Interesting Facts about 4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium Chloride

The compound 4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium chloride is a fascinating molecule that draws interest from both organic chemistry and medicinal chemistry perspectives. Here are some notable aspects of this compound:

  • Diverse Applications: This compound is part of a class of isoquinolinium salts, which are often explored for their potential in pharmaceuticals, particularly as anti-cancer agents and antimicrobial agents.
  • Structural Complexity: The presence of a dioxole ring system in the structure contributes to its unique chemical reactivity. Dioxole rings are known for their electron-rich character, which may influence the reactivity of the compound in various chemical reactions.
  • Mechanism of Action: Compounds with similar structures have exhibited various mechanisms of action in biological systems, highlighting their potential use in drugs that can target specific biological pathways.
  • Synthetic Versatility: The synthesis of isoquinoline derivatives allows for the modification of the dioxole group, leading to a wide range of potential derivatives that can be tailored for specific applications.
  • Research Interest: This compound is part of ongoing research in the field of organometallic and coordination chemistry, where scientists are exploring its binding properties and interactions with metal ions.

Overall, the compound 4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium chloride showcases the rich intersection of organic chemistry and medicinal applications, making it a subject of interest for both researchers and students alike.

Synonyms
4-Methoxy-1,3-dioxolo(4,5-g)isoquinoline hydrochloride
5263-79-6
1,3-DIOXOLO(4,5-g)ISOQUINOLINE, 4-METHOXY-, HYDROCHLORIDE