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4-methoxy-3-nitro-N-phenylbenzamide

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Identification
Molecular formula
C14H12N2O4
CAS number
51852-81-4
IUPAC name
4-methoxy-3-nitro-N-phenyl-benzamide
State
State

At room temperature, 4-methoxy-3-nitro-N-phenylbenzamide is in a solid state. It is stable under normal conditions and has a well-defined crystalline form.

Melting point (Celsius)
161.80
Melting point (Kelvin)
434.95
Boiling point (Celsius)
375.80
Boiling point (Kelvin)
648.95
General information
Molecular weight
274.27g/mol
Molar mass
274.2650g/mol
Density
1.3394g/cm3
Appearence

4-methoxy-3-nitro-N-phenylbenzamide typically appears as a crystalline solid, exhibiting a yellow or orange hue due to the presence of the nitro group. The compound is crystalline in nature and forms structured lattices which determine its solid appearance.

Comment on solubility

Solubility of 4-methoxy-3-nitro-N-phenyl-benzamide

4-methoxy-3-nitro-N-phenyl-benzamide, a compound with distinct functional groups, exhibits unique solubility properties that can be influenced by various factors. Generally speaking, the solubility of this compound can be characterized in several key ways:

  • Solvents: This compound is likely to be soluble in polar organic solvents such as dichloromethane and acetone. However, it may show limited solubility in non-polar solvents like hexane due to its aromatic nature.
  • Hydrophilicity vs. Hydrophobicity: The presence of the methoxy group enhances its polarity, promoting solubility in polar solvents while the larger hydrophobic aromatic structures may hinder solubility in water.
  • Temperature Influence: As with many organic compounds, the solubility of 4-methoxy-3-nitro-N-phenyl-benzamide can increase with temperature, allowing for better dissolution in various solvents.
  • pH Effects: The acid-base properties of the benzamide group may also influence solubility. In slightly basic conditions, the compound might have increased solubility due to deprotonation.

In conclusion, while the solubility of 4-methoxy-3-nitro-N-phenyl-benzamide can be predicted through its chemical structure, it is essential to consider the medium, temperature, and pH for practical applications. As a result, one may find that "the right solvent can make all the difference" in maximizing this compound's solubility.

Interesting facts

Interesting Facts about 4-Methoxy-3-Nitro-N-Phenyl-Benzamide

4-Methoxy-3-nitro-N-phenyl-benzamide is a fascinating compound that falls within the category of aromatic amides. It has gained attention in various fields of research due to its potential applications and interesting structural features. Here are some captivating aspects of this compound:

  • Structural Features: The compound contains both a methoxy group and a nitro group on the benzene ring. This unique combination can result in intriguing electronic and steric effects that influence its reactivity.
  • Pharmaceutical Potential: Compounds like 4-methoxy-3-nitro-N-phenyl-benzamide are often explored for their biological activities, making them candidates for developing new drugs. The presence of the nitro group can enhance the pharmacological profile of the compound.
  • Synthesis: This compound can be synthesized through various chemical pathways, allowing chemists to explore different methods that could lead to more efficient synthesis or higher yields.
  • Analytical Techniques: Characterization of 4-methoxy-3-nitro-N-phenyl-benzamide often involves advanced analytical techniques such as NMR spectroscopy and mass spectrometry, which provide valuable insights into its structure and purity.
  • Research Applications: Beyond medicinal chemistry, this compound could be used in material science and organic electronics, where nitro-substituted aromatic compounds are of particular interest.

"A well-structured compound can lead to unexpected discoveries in the lab." This quote emphasizes the importance of understanding chemical structures in exploring their potential use in various applications.

In summary, 4-methoxy-3-nitro-N-phenyl-benzamide exemplifies the complexity and beauty of organic chemistry, with continuing research revealing its myriad capabilities and implications for future studies.

Synonyms
4-METHOXY-3-NITRO-N-PHENYLBENZAMIDE
97-32-5
3-Nitro-p-anisanilide
3-NITRO-4-METHOXYBENZANILIDE
p-Anisanilide, 3-nitro-
Benzamide, 4-methoxy-3-nitro-N-phenyl-
CCRIS 5842
EINECS 202-572-9
NSC 50649
4-Methoxy-3-nitrobenzanilide
BRN 3397509
DTXSID7025558
DTXCID205558
2-12-00-00258 (Beilstein Handbook Reference)
NSC-50649
Oprea1_224729
4E8U86FE5W
CHEMBL1325964
SCHEMBL19034437
NSC50649
Tox21_200743
STL139190
AKOS000371586
CAS-97-32-5
Methoxy-3-nitro-N-phenylbenzamide. 4-
NCGC00091837-01
NCGC00091837-02
NCGC00091837-03
NCGC00258297-01
NCI60_004220
DB-057671
NS00022913
Z27782852
202-572-9