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Berberine bromide

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Identification
Molecular formula
C20H18NO4Br
CAS number
1041-24-1
IUPAC name
4-methoxy-6-propyl-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;bromide
State
State

At room temperature, berberine bromide is typically found in a solid state.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
372.25g/mol
Molar mass
372.2500g/mol
Density
1.3200g/cm3
Appearence

Berberine bromide appears as a crystalline solid. It may have a yellow color, similar to other salts of berberine, and is typically odorless. When observed under a microscope, the crystals can appear as orthorhombic and have a needle-like or prismatic shape.

Comment on solubility

Solubility of 4-methoxy-6-propyl-[1,3]dioxolo[4,5-g]isoquinolin-6-ium bromide

The solubility of 4-methoxy-6-propyl-[1,3]dioxolo[4,5-g]isoquinolin-6-ium bromide is influenced by its unique chemical structure and ionic characteristics. Generally, ionic compounds like this bromide salt demonstrate varying levels of solubility in different solvents, often exhibiting the following trends:

  • Polar Solvents: This compound is likely to be soluble in water due to its ionic nature, which facilitates interaction with polar solvents.
  • Non-polar Solvents: Solubility in non-polar solvents may be limited, as the compound’s ionic character does not favor interactions with non-polar molecules.
  • Temperature Dependence: The solubility can also depend on temperature; generally, higher temperatures tend to increase solubility, allowing for greater dissolution of ionic salts in solution.

Furthermore, it’s essential to consider that salt formation plays a crucial role in enhancing solubility. The presence of the bromide ion can increase the interaction with water molecules, thereby dissolving more readily. As one might summarize, "The greater the ionic character, the greater the potential for solubility in polar environments."

In conclusion, while this compound exhibits solubility characteristics suitable for interaction with polar solvents such as water, its behavior in other contexts should be explored through empirical studies for a comprehensive understanding.

Interesting facts

Interesting Facts about 4-Methoxy-6-propyl-[1,3]dioxolo[4,5-g]isoquinolin-6-ium bromide

This fascinating compound, known as 4-methoxy-6-propyl-[1,3]dioxolo[4,5-g]isoquinolin-6-ium bromide, belongs to the isoquinoline family, which is notable for its diverse biological properties. Here are some intriguing aspects of this compound:

  • Structure: The unique dioxolo ring present in this compound contributes to its complex three-dimensional structure and can influence intermolecular interactions.
  • Biological Activity: Compounds related to isoquinolines often exhibit various pharmacological properties, including antimicrobial and antitumor activities.
  • Research Applications: It may serve as a useful tool in medicinal chemistry for developing new therapeutics due to its structural attributes.
  • Solubility and Ionization: The presence of the bromide moiety can significantly influence the compound's solubility and ionization in biological systems, affecting its bioavailability.
  • Potential Uses: Considered for applications in drug design, particularly in the field of neurochemistry, where isoquinolines have shown promising results in modulating neurotransmission.

The compound exemplifies how structural differences in organic molecules can lead to varied biological outcomes. Its study not only reflects cutting-edge research in organic chemistry but also emphasizes the importance of multidisciplinary approaches in the quest for new therapeutic agents.

As research progresses, this compound offers exciting potential for discovering novel therapeutic strategies, making it a significant subject of interest within the scientific community.

Synonyms
4-Methoxy-6-propyl-1,3-dioxolo(4,5-g)isoquinolinium bromide
15288-33-2
1,3-DIOXOLO(4,5-g)ISOQUINOLINIUM, 4-METHOXY-6-PROPYL-, BROMIDE
DTXSID50934624
Methyl(6-propyl-2H-[1,3]dioxolo[4,5-g]isoquinolin-4(6H)-ylidene)oxidanium bromide