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Noscapine

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Identification
Molecular formula
C22H23NO7
CAS number
128-62-1
IUPAC name
4-methoxy-8,9-dimethyl-7,9-dihydro-6H-[1,3]dioxolo[4,5-h]isoquinoline
State
State

At room temperature, noscapine is typically found as a solid. It is stable in this state when kept free from moisture and maintained in a suitable storage environment.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
445.60
Boiling point (Kelvin)
718.75
General information
Molecular weight
413.46g/mol
Molar mass
413.4620g/mol
Density
1.3180g/cm3
Appearence

Noscapine appears as a white or slightly yellow crystalline powder. It is mostly available in its pure form and has a characteristic crystalline texture.

Comment on solubility

Solubility of 4-methoxy-8,9-dimethyl-7,9-dihydro-6H-[1,3]dioxolo[4,5-h]isoquinoline

The solubility of 4-methoxy-8,9-dimethyl-7,9-dihydro-6H-[1,3]dioxolo[4,5-h]isoquinoline can vary significantly depending on environmental conditions. Understanding its solubility is crucial for various applications, including pharmacology and materials science.

Factors Influencing Solubility

  • Polarity: Due to the presence of the methoxy group, this compound exhibits a degree of polarity, which can enhance its solubility in polar solvents.
  • Hydrogen Bonding: The dioxole ring structure may facilitate hydrogen bonding with solvents, further increasing solubility.
  • Temperature: Generally, an increase in temperature can lead to enhanced solubility for many organic compounds.

It’s important to note that this compound may demonstrate limited solubility in non-polar solvents due to its structural complexity. Therefore, one might expect:

  • High solubility: In polar protic solvents like methanol and ethanol.
  • Moderate to low solubility: In non-polar solvents such as hexane or benzene.

In conclusion, the solubility of 4-methoxy-8,9-dimethyl-7,9-dihydro-6H-[1,3]dioxolo[4,5-h]isoquinoline is influenced by several factors, and its behavior can vary, making it essential to conduct specific solubility tests for practical applications. Understanding these parameters can pave the way for optimizing its use in various fields.

Interesting facts

Interesting Facts about 4-Methoxy-8,9-Dimethyl-7,9-Dihydro-6H-[1,3]Dioxolo[4,5-h]Isoquinoline

4-Methoxy-8,9-dimethyl-7,9-dihydro-6H-[1,3]dioxolo[4,5-h]isoquinoline is a fascinating compound that belongs to a unique class of heterocyclic aromatic compounds known as isoquinolines. This compound exhibits several intriguing properties and potential applications in various fields:

  • Structural Diversity: The presence of multiple functional groups and rings in its structure contributes to the compound's chemical reactivity and versatility in synthesis.
  • Potential Therapeutic Uses: Compounds containing isoquinoline skeletons have been extensively studied for their biological activities, including anticancer, anti-inflammatory, and antimicrobial properties.
  • Natural Occurrence: Isoquinolines are often found in various plant alkaloids, suggesting that this compound may share some similarities with naturally occurring bioactive molecules.
  • Synthetic Routes: Researchers have developed numerous synthetic methods for creating isoquinoline derivatives, showcasing the compound's importance in organic synthesis.
  • Interest in Functionalization: The presence of methoxy and dimethyl groups allows for the possibility of further functionalization, making it a valuable intermediate in the development of new drugs and materials.

As a chemist or a student in the field, one might find the study of this compound particularly rewarding. As quoted by renowned chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." This sentiment rings true in the exploration of isoquinoline derivatives, which can lead to groundbreaking discoveries in medicinal chemistry.

Overall, 4-methoxy-8,9-dimethyl-7,9-dihydro-6H-[1,3]dioxolo[4,5-h]isoquinoline exemplifies the rich potential of organic compounds and encourages further research into their multifaceted applications.

Synonyms
PNFBXEKHLUDPIM-UHFFFAOYSA-N
AKOS000277817
HY-119478
CS-0068479
Q3259317
6-methoxy-1,2-dimethyl-7,8-methylenedioxy-1,2,3,4-tetrahydroisoquinoline