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Thalidezine

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Identification
Molecular formula
C20H27ClN3O
CAS number
40064-34-4
IUPAC name
4-methoxy-N-(2-pyridylmethyl)-N-(2-pyrrolidin-1-ium-1-ylethyl)aniline;chloride
State
State

At room temperature, this compound is typically solid. It exists primarily in its salt form when combined with hydrochloric acid, as it is here specified as a chloride.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
375.92g/mol
Molar mass
375.9170g/mol
Density
1.2200g/cm3
Appearence

The compound appears as a white to off-white crystalline powder. It can form solid salts such as chlorides when combined with acids.

Comment on solubility

Solubility of 4-methoxy-N-(2-pyridylmethyl)-N-(2-pyrrolidin-1-ium-1-ylethyl)aniline;chloride

The solubility of 4-methoxy-N-(2-pyridylmethyl)-N-(2-pyrrolidin-1-ium-1-ylethyl)aniline;chloride is influenced by its structure and ionic character. This compound features a quaternary ammonium ion due to the presence of the pyrrolidinium group, which typically promotes solubility in polar solvents. Here are some key considerations:

  • Polar Solvents: This compound is likely to be highly soluble in water and other polar solvents due to its ionic nature.
  • Non-Polar Solvents: It may exhibit limited solubility in non-polar solvents owing to the hydrophilic quaternary ammonium group.
  • Hydrogen Bonding: The presence of electronegative atoms can enhance solubility by facilitating hydrogen bonding interactions with solvent molecules.
  • Temperature Dependence: Solubility may vary significantly with temperature changes, as increasing temperature can enhance solubility for ionic compounds.

In summary, one could say, "The solubility of this compound is generally expected to be high in aqueous solutions, making it suitable for various applications where polar environments are prevalent."

Interesting facts

Interesting Facts about 4-Methoxy-N-(2-pyridylmethyl)-N-(2-pyrrolidin-1-ium-1-ylethyl)aniline;chloride

This intriguing compound belongs to a broader class of chemicals known as quaternary ammonium compounds, which are often characterized by their strong interaction with biological materials and their role in various applications.

Key Features

  • Pharmacological Potential: Due to its unique structure, the compound exhibits potential in pharmacology, particularly as a therapeutic agent. Compounds with similar functionalities are often studied for their impacts on the central nervous system.
  • Pyridine and Pyrrolidine Rings: The presence of both pyridine and pyrrolidine in the structure adds to its versatility and reactivity, making it interesting for synthetic organic chemistry.
  • Cationic Nature: Being a quaternary ammonium salt, this compound has cationic properties, leading to its significant applications in antimicrobial formulations and surfactants.

Applications in Research

As a subject of research, this compound holds promise in various fields:

  • Drug Development: Its interaction with biological systems is of considerable interest, potentially leading to novel drug formulations.
  • Material Science: It can be utilized in the development of polymers and materials with specific characteristics due to its charge and hydrophilicity.
  • Biological Studies: The compound could serve as a probe or a tool in biological studies to understand cellular mechanisms.

In conclusion, the compound 4-methoxy-N-(2-pyridylmethyl)-N-(2-pyrrolidin-1-ium-1-ylethyl)aniline;chloride invites exciting explorations in chemistry and related fields, with its complex structure offering multiple avenues for innovative applications. As stated by many researchers in the field, “the functionalization within organic compounds is often key to unlocking their full potential.”

Synonyms
Aniline, p-methoxy-N-(2-pyridylmethyl)-N-(2-(1-pyrrolidinyl)ethyl)-, hydrochloride
27439-42-5
N-(2-Picolyl)-N-(p-anisyl)-N-(2-pyrrolidinyl)amine hydrochloride
RefChem:319674