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4'-Methoxyacetophenone

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Identification
Molecular formula
C13H11NO2
CAS number
5362-81-4
IUPAC name
(4-methoxyphenyl)-(4-pyridyl)methanone
State
State

At room temperature, (4-Methoxyphenyl)-(4-pyridyl)methanone maintains a solid state. Its structure is stable under normal atmospheric conditions, retaining the crystalline form that it is typically found in.

Melting point (Celsius)
82.00
Melting point (Kelvin)
355.15
Boiling point (Celsius)
320.60
Boiling point (Kelvin)
593.75
General information
Molecular weight
213.24g/mol
Molar mass
213.2420g/mol
Density
1.2130g/cm3
Appearence

(4-Methoxyphenyl)-(4-pyridyl)methanone appears as a crystalline solid. It generally presents itself in a white to off-white color. The compound is known for its well-formed crystal structure, often appearing as fine needles or powder.

Comment on solubility

Solubility of (4-methoxyphenyl)-(4-pyridyl)methanone

(4-methoxyphenyl)-(4-pyridyl)methanone is a compound characterized by its unique molecular structure, which influences its solubility behavior in various solvents. The solubility of this compound can be described as follows:

  • Polar Solvents: This compound exhibits limited solubility in water due to the hydrophobic nature of the aromatic rings present in its structure.
  • Organic Solvents: It tends to dissolve well in organic solvents such as methanol and ethanol. This is primarily attributed to the combined effects of polar functional groups and hydrophobic interactions.
  • Temperature Dependency: The solubility may increase with temperature, as is common with many organic compounds. Higher temperatures can enhance molecular motion, resulting in better solvation.
  • pH Influences: The solubility profile can also be affected by the pH of the solution, particularly if the compound can undergo protonation or deprotonation.

In summary, while (4-methoxyphenyl)-(4-pyridyl)methanone shows a tendency to be insoluble in water, it is more compatible with organic solvents, making its applications more favorable in non-aqueous environments. As stated, “the solubility of a compound provides key insights into its potential uses and behaviors in various chemical settings.”

Interesting facts

Interesting Facts about (4-methoxyphenyl)-(4-pyridyl)methanone

(4-methoxyphenyl)-(4-pyridyl)methanone is a fascinating compound that falls under the category of ketones. Its structure combines two aromatic systems, a methoxy-substituted phenyl group and a pyridyl group, making it noteworthy in both organic synthesis and medicinal chemistry.

Chemical Significance

The presence of both the methoxy and pyridyl groups enhances its reactivity, making it suitable for various chemical transformations. Key points of interest include:

  • Reactivity: The carbonyl group in ketones often participates in nucleophilic addition reactions, which can be exploited in the synthesis of more complex molecules.
  • Biological Activity: Compounds containing pyridine rings have been found to exhibit a variety of biological properties, including anti-inflammatory and antimicrobial activities, which make them candidates for pharmaceutical research.
  • Supramolecular Chemistry: The unique combination of molecular interactions in this compound can lead to interesting supramolecular architectures, paving the way for developments in materials science.

Applications

Due to its intriguing structure, (4-methoxyphenyl)-(4-pyridyl)methanone has potential applications in different fields:

  • Pharmaceuticals: It could act as a lead compound for drug development, particularly in targeting diseases where pyridine derivatives have shown promise.
  • Synthetic Chemistry: As a versatile intermediate, it can be utilized in the synthesis of dyes, agrochemicals, and other useful organic compounds.
  • Material Science: Its properties might contribute to developing innovative materials such as sensors and polymers.

In conclusion, (4-methoxyphenyl)-(4-pyridyl)methanone is more than just a chemical entity; it embodies the bridge between various disciplines in chemistry and offers a myriad of opportunities for research and application. Overall, studying compounds like this one can lead to exciting scientific discoveries and advancements!

Synonyms
14548-47-1
(4-Methoxyphenyl)(4-pyridyl)methanone
4-(4-Methoxybenzoyl)pyridine
(4-Methoxyphenyl)(4-pyridyl) ketone
(4-methoxyphenyl)-pyridin-4-ylmethanone
Methanone, (4-methoxyphenyl)-4-pyridinyl-
MFCD01716434
KETONE, (p-METHOXYPHENYL) 4-PYRIDYL
p-Anisyl 4-pyridyl ketone
p-Methoxyphenyl 4-pyridyl ketone
Ketone, p-anisyl 4-pyridyl
Pyridine, 4-(4-methoxybenzoyl)-
BRN 0392709
SCHEMBL11276575
DTXSID70163055
AKOS000279636
(4-methoxyphenyl)-(4-pyridyl)methanone
(4-Methoxyphenyl)-4-pyridinyl-methanone
AS-53610
SY058187
P16757
EN300-1072057
Z385418482