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4-Methoxybenzyl alcohol

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Identification
Molecular formula
C8H10O2
CAS number
105-13-5
IUPAC name
(4-methoxyphenyl)methanol
State
State

4-Methoxybenzyl alcohol is typically found as a solid at room temperature.

Melting point (Celsius)
63.00
Melting point (Kelvin)
336.15
Boiling point (Celsius)
259.40
Boiling point (Kelvin)
532.50
General information
Molecular weight
138.17g/mol
Molar mass
138.1660g/mol
Density
1.1046g/cm3
Appearence

4-Methoxybenzyl alcohol appears as a white to light yellow crystalline solid. It can also appear as colorless crystals depending on its purity and the method of crystallization.

Comment on solubility

Solubility of (4-Methoxyphenyl)methanol

The solubility of (4-methoxyphenyl)methanol, also known by its IUPAC name, can be influenced by several factors, primarily its molecular structure and the polarity of its functional groups. This compound features a methoxy group, which generally enhances the solubility of organic compounds in polar solvents.

  • Polarity: The presence of the methoxy group provides a degree of polarity, allowing for good solubility in polar solvents such as water.
  • Hydrophilic vs. Hydrophobic: While the aromatic ring is relatively hydrophobic, the overall solubility is impacted by the balance between the hydrophilic methoxy group and the hydrophobic nature of the phenyl ring.
  • Solvent Compatibility: As a rule of thumb, (4-methoxyphenyl)methanol is expected to be more soluble in alcohols, ethers, and less polar environments compared to purely aqueous solutions.

In practical terms:

  1. It shows significant solubility in organic solvents.
  2. Test for solubility in various solvents to determine its behavior in specific applications.
  3. Always consider temperature, as increased temperatures can enhance the solubility of many organic compounds.

In summary, understanding the solubility characteristics of (4-methoxyphenyl)methanol is crucial for its application in fields such as pharmaceuticals and material science, as it dictates its usability in different solvent systems.

Interesting facts

Interesting Facts about (4-methoxyphenyl)methanol

(4-methoxyphenyl)methanol, also known as p-methoxybenzyl alcohol, is an intriguing compound with a variety of fascinating attributes. This organic compound is identified by the presence of both an aromatic ring and an alcohol functional group, culminating in unique chemical behavior and applications.

Chemical Structure and Properties

The structure of (4-methoxyphenyl)methanol consists of a methoxy group (-OCH3) attached to the aromatic ring, providing interesting reactivity:

  • Functional Groups: Contains a phenolic feature that influences its reactivity in various chemical reactions.
  • Chemical Behavior: The presence of the methoxy group can enhance nucleophilicity, making the compound suitable for roles as an intermediate in organic synthesis.

Applications in Industry

Beyond its structural properties, (4-methoxyphenyl)methanol has notable applications:

  • Pharmaceuticals: Used in the synthesis of various pharmaceutical compounds, beneficial for drug development.
  • Fragrance Development: Its pleasant scent profile allows it to be incorporated into fragrances and flavorings.
  • Research Use: Serves as a valuable intermediate in the synthesis of more complex molecules for academic research.

Biological Significance

Additionally, the compound captures attention due to its potential biological roles:

  • Antioxidant Properties: Some studies suggest potential antioxidant activities, making it a candidate for further research in health sciences.
  • Biological Assays: Its applicability in biological assays could help investigate its mechanisms of action.

In summary, (4-methoxyphenyl)methanol is not just another organic compound; its unique structural characteristics, combined with its wide range of applications in industries and potential biological significance, make it an exciting subject for chemists and researchers alike. Exploring its chemistry could unveil further intricacies of how such compounds can be harnessed for innovation and improvement in health and industry.

Synonyms
4-METHOXYBENZYL ALCOHOL
105-13-5
(4-Methoxyphenyl)methanol
Anisyl alcohol
Anise alcohol
p-Methoxybenzyl alcohol
p-Anisyl alcohol
Benzenemethanol, 4-methoxy-
Anisic alcohol
p-Anisol alcohol
4-Methoxybenzenemethanol
Benzyl alcohol, p-methoxy-
Anis alcohol
Anisalcohol, p-
4-Methoxybenzylalcohol
FEMA No. 2099
Anisyl alcohol (natural)
NSC 2151
CCRIS 5111
4-Anisylalcohol
EINECS 203-273-6
MFCD00004653
BRN 0636654
7N6XGV3U49
DTXSID6044357
AI3-01170
p-methoxy-benzyl alcohol
NSC-2151
para-methoxybenzyl alcohol
(4-methoxyphenyl)-methanol
ANISE ALCOHOL [MI]
(4-Methoxy-phenyl)-methanol
ANISYL ALCOHOL [FCC]
ANISYL ALCOHOL [FHFI]
DTXCID4024357
PARA METHOXYBENZYL ALCOHOL
EC 203-273-6
4-06-00-05909 (Beilstein Handbook Reference)
(4-(METHYLOXY)PHENYL)METHANOL
A1BDD
[4-(methyloxy)phenyl]methanol
UNII-7N6XGV3U49
Anisalkohol
p-anisalcohol
pAnisol alcohol
pAnisyl alcohol
Anisalcohol, p
ar-anisyl alcohol
JandaJel(TM)-Wang
p-methoxybenzylalcohol
pMethoxybenzyl alcohol
4methoxybenzyl alcohol
4Methoxybenzenemethanol
4-methoxyphenylmethanol
4-methoxy-benzylalcohol
4-methoxylbenzyl alcohol
4-methyoxybenzyl alcohol
(4Methoxyphenyl)methanol
Benzyl alcohol, pmethoxy
4-methoxy-benzenemethanol
4-methoxy-benzyl alcohol
4-(Hydroxymethyl)anisole
Benzenemethanol, 4methoxy
bmse010025
DSSTox_CID_24357
DSSTox_RID_82376
4-methoxyphenylmethyl alcohol
DSSTox_GSID_47486
SCHEMBL27329
WLN: Q1R DO1
(4-Methoxyphenyl)methanol #
ANISE ALCOHOL [INCI]
p-Anisyl alcohol;Anise alcohol
4-Methoxybenzyl alcohol, 98%
CHEMBL294431
FEMA 2099
NSC2151
1-methoxy-4-hydroxymethyl-benzene
CHEBI:193647
BENZENEMETHANOL,AR-METHOXY-
BCP26725
STR00774
Tox21_301115
Tox21_302521
BBL027471
STL146342
Anisyl alcohol, >=98%, FCC, FG
AKOS000249369
Anisyl alcohol, natural, >=98%, FG
CS-W016493
FM47002
HY-W015777
PB47798
PS-4037
NCGC00248292-01
NCGC00255015-01
NCGC00256684-01
CAS-105-13-5
CAS-1331-81-3
4-METHOXY-[7-13C]-BENZYL ALCOHOL
DB-003500
4-Methoxybenzyl alcohol, analytical standard
M0107
NS00009442
EN300-16200
Anisyl alcohol 1000 microg/mL in Acetonitrile
D77792
Q548873
Z54603098
F0001-0102
203-273-6
JandaJel(TM)-Wang, 100-200 mesh, extent of labeling: 1.0 mmol/g loading, 2 % cross-linked