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4-Methoxyquinazoline

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Identification
Molecular formula
C9H8N2O
CAS number
5412-87-9
IUPAC name
4-methoxyquinazoline
State
State

4-Methoxyquinazoline is a solid at room temperature.

Melting point (Celsius)
146.00
Melting point (Kelvin)
419.15
Boiling point (Celsius)
299.00
Boiling point (Kelvin)
572.15
General information
Molecular weight
160.17g/mol
Molar mass
160.1710g/mol
Density
1.2360g/cm3
Appearence

4-Methoxyquinazoline is generally a light yellow crystalline solid. Its appearance might vary slightly based on the purity and the specific form it is synthesized or purified in.

Comment on solubility

Solubility of 4-methoxyquinazoline

When it comes to the solubility of 4-methoxyquinazoline, this compound exhibits specific characteristics that are vital to its potential applications. Solubility is influenced by several factors including temperature, pH, and the nature of solvents.

Characteristics of Solubility

  • Solvent Polarity: 4-methoxyquinazoline tends to be more soluble in organic solvents due to its non-polar aromatic ring structure. Solvents such as ethanol or dimethyl sulfoxide (DMSO) can effectively dissolve this compound.
  • Temperature Effects: Increased temperature generally enhances solubility. This behavior can be particularly noted in the study of organic compounds, where higher temperatures may facilitate the dissolution process.
  • Aqueous Solubility: In contrast, its solubility in water is likely to be limited, indicating a preference for non-aqueous environments.

To summarize, while 4-methoxyquinazoline shows reasonable solubility in organic solvents, it demonstrates limited solubility in water. Understanding these solubility properties not only aids in the practical usage of the compound but also guides further research into its chemical behavior and potential applications.

Interesting facts

Interesting Facts about 4-Methoxyquinazoline

4-Methoxyquinazoline is a fascinating compound that has captured the interest of researchers in various fields of chemistry, pharmacology, and medicinal applications. Here are some noteworthy insights about this intriguing molecule:

  • Structural Highlights: The quinazoline backbone is a heterocyclic structure that features nitrogen atoms within its rings, which significantly enhances its chemical reactivity and potential biological activity.
  • Pharmacological Potential: Compounds related to quinazoline have been widely studied for their antimicrobial, anticancer, and anti-inflammatory properties. 4-Methoxyquinazoline, in particular, has shown promise in preliminary research.
  • Importance in Drug Development: The modification of quinazoline derivatives, like 4-methoxyquinazoline, can lead to the discovery of new therapeutic agents targeting various diseases. This modification aspect makes it a valuable compound in medicinal chemistry.
  • Role in Organic Synthesis: 4-Methoxyquinazoline serves as a useful building block in organic synthesis, facilitating the creation of complex molecules through various chemical reactions.
  • Scientific Research: Studies exploring its mechanisms of action often involve in vitro and in vivo models, contributing to a deeper understanding of its possible effects on cellular processes.

In summary, 4-methoxyquinazoline stands out as an intriguing compound with a variety of potential applications in science and medicine. Its unique structural features and interactions offer endless possibilities for exploration and innovation in chemical research.

Synonyms
4-Methoxyquinazoline
QUINAZOLINE, 4-METHOXY-
NSC 45918
BRN 0124931
DTXSID80167600
5-23-11-00440 (Beilstein Handbook Reference)
DTXCID0090091
QHHPPKHDJVVPQH-UHFFFAOYSA-N
16347-95-8
7D3Q6G9DJ4
NSC-45918
NSC45918
UNII-7D3Q6G9DJ4
SCHEMBL7053228
SCHEMBL7976154
DS-001380