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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
4-methyl-1-[(5-nitro-2-furyl)methyleneamino]imidazolidin-2-one
State
State

Nitrofurazone is in a solid state at room temperature, existing as a powder or crystalline substance.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
313.00
Boiling point (Kelvin)
586.15
General information
Molecular weight
198.16g/mol
Molar mass
198.1560g/mol
Density
1.5708g/cm3
Appearence

Nitrofurazone is typically an odorless, pale yellow crystalline powder. It may appear as fine crystals or sometimes as a more coarse powder. Due to its vivid yellow color, it is often distinct and identifiable. This compound is usually not hygroscopic, remaining crisp in its solid form when stored correctly.

Comment on solubility

Solubility of 4-methyl-1-[(5-nitro-2-furyl)methyleneamino]imidazolidin-2-one

The solubility of the compound 4-methyl-1-[(5-nitro-2-furyl)methyleneamino]imidazolidin-2-one can vary greatly depending on several factors. Understanding its solubility characteristics is crucial for applications in pharmaceutical, agricultural, and chemical industries.

Key Factors Affecting Solubility:

  • Polarity: The presence of the nitro group and imidazolidinone framework may enhance polarity, influencing solubility in polar solvents.
  • Hydrogen Bonding: Functional groups capable of hydrogen bonding can significantly increase solubility in solvents like water.
  • pH Dependence: The solubility might change with pH, especially if the compound contains ionizable groups.

Solubility itself can be described as:

  • High Solubility: If the compound readily dissolves in water or common organic solvents.
  • Moderate Solubility: If it dissolves moderately well under certain conditions but may precipitate under others.
  • Poor Solubility: If the compound shows minimal to no dissolution in most solvents, potentially necessitating solubilizing agents.

In conclusion, while specific solubility data for 4-methyl-1-[(5-nitro-2-furyl)methyleneamino]imidazolidin-2-one may not be widely reported, understanding the implications of its chemical structure aids in predicting its behavior in various environments. It’s important to conduct empirical studies to quantify exact solubility under specified conditions.

Interesting facts

Interesting Facts about 4-methyl-1-[(5-nitro-2-furyl)methyleneamino]imidazolidin-2-one

This fascinating compound, 4-methyl-1-[(5-nitro-2-furyl)methyleneamino]imidazolidin-2-one, is a member of the imidazolidinone class, showcasing intriguing properties that spark interest among chemists and researchers alike.

Key Features

  • Structural Complexity: The compound consists of an imidazolidinone core coupled with a nitrofuran ring, presenting a versatile scaffold for various chemical modifications and pharmaceutical applications.
  • Biological Significance: Some derivatives of imidazolidinones are known for their biological activities, including antimicrobial and anticancer properties, prompting research into their therapeutic potential.
  • Reactivity: The methyleneamino group can participate in various chemical reactions, including nucleophilic substitutions and condensations, offering avenues for synthetic chemists to explore new compounds.

As noted by researchers, “The rich chemistry of oxoamides provides numerous opportunities for innovation in drug design.” This sentiment rings especially true for compounds like this one that marry unique structural features with biological activity.

Applications in Research

In medicinal chemistry, compounds with similar structures have been investigated for:

  • Inhibition of specific enzyme targets
  • Modulation of multiple biological pathways
  • Development of novel therapeutic agents

With ongoing studies exploring new derivatives and their implications, this compound represents a small but significant branch of the broader field of heterocyclic chemistry, showcasing how slight modifications can lead to diverse functional properties.

Overall, 4-methyl-1-[(5-nitro-2-furyl)methyleneamino]imidazolidin-2-one stands at the intersection of structural chemistry and pharmacology, inviting further exploration and innovation.

Synonyms
4-methyl-1-{[(5-nitrofuran-2-yl)methylidene]amino}imidazolidin-2-one
DTXSID00860267
NS00120414