4-Methyl-1,2,5-oxadiazol-3-amine | Solubility of Things

Identification

Molecular formula

C₃H₅N₃O

CAS number

6968-30-3

IUPAC name

4-methyl-1,2,5-oxadiazol-3-amine

State

At room temperature, 4-Methyl-1,2,5-oxadiazol-3-amine exists as a solid. The substance is stable under normal conditions but should be stored away from sources of moisture and extreme temperatures to maintain its integrity and prevent decomposition. In terms of handling, it is advisable to ensure the area is well-ventilated to avoid any irritation that may arise should it sublimate or react to release fumes.

Melting point (Celsius)

57.00

Melting point (Kelvin)

330.15

Boiling point (Celsius)

209.00

Boiling point (Kelvin)

482.15

General information

Molecular weight

99.10g/mol

Molar mass

99.1020g/mol

Density

1.2170g/cm³

Appearence

4-Methyl-1,2,5-oxadiazol-3-amine typically appears as a solid crystalline substance. The crystals can vary in color but are generally white to off-white. The compound may also be found in powdered form depending on the method of preparation and handling. Like many crystalline solids, it is likely to be characterized by a specific crystal structure, though the exact prominent crystal form may depend on the environmental conditions surrounding its synthesis or storage.

Comment on solubility

Solubility of 4-methyl-1,2,5-oxadiazol-3-amine

The solubility of 4-methyl-1,2,5-oxadiazol-3-amine can be influenced by several factors, including its molecular structure and the solvent used. In general, the solubility characteristics of this compound may be characterized as follows:

Polar Solvents: Due to the presence of nitrogen atoms within the oxadiazole ring, it is likely to exhibit increased solubility in polar solvents like water and alcohols.
Non-Polar Solvents: Conversely, its solubility in non-polar solvents may be limited, owing to the lack of significant hydrophobic interactions in the compound.
Temperature Influence: An increase in temperature often enhances solubility, leading to better dissolution rates in various solvents.
Concentration of Solvent: Higher concentrations of the compound may lead to incomplete dissolution, particularly in less compatible solvents.

In summary, while 4-methyl-1,2,5-oxadiazol-3-amine is expected to be soluble in polar media, it is critical to test its solubility under practical conditions to fully understand its behavior in different environments. As a general quote summarized, "The solubility of a compound tells us as much about its interactions as it does about its potential applications." Thus, careful consideration of the solvent choice is essential when working with this compound.

Interesting facts

Interesting Facts about 4-methyl-1,2,5-oxadiazol-3-amine

4-methyl-1,2,5-oxadiazol-3-amine is a fascinating compound in the field of organic chemistry, particularly known for its heterocyclic structure featuring an oxadiazole ring. This compound stands out due to several intriguing aspects:

Heterocyclic Chemistry: The oxadiazole ring is a five-membered aromatic structure that contains two nitrogen atoms. This unique configuration makes compounds like 4-methyl-1,2,5-oxadiazol-3-amine valuable in medicinal chemistry and materials science.
Biological Significance: Compounds with oxadiazole rings have garnered attention for their biological activities. They have been studied for potential antimicrobial and antitumor properties, opening doors to new pharmaceutical developments.
Versatile Functional Groups: The presence of the amino group (–NH₂) in this compound allows it to participate in various chemical reactions, potentially serving as a building block for synthesizing other complex molecules.
Research and Applications: Recent studies focus on exploring its application in agrochemicals and polymers. The compound's unique properties may lead to innovative solutions in crop protection or material design.

As noted by chemists, "Heterocycles are the backbone of organic chemistry." The review of compounds like 4-methyl-1,2,5-oxadiazol-3-amine emphasizes the importance of understanding such structures for future discoveries in synthetic chemistry.

In summary, 4-methyl-1,2,5-oxadiazol-3-amine is not just another compound; it symbolizes the intersection of applied research and fundamental organic chemistry. Its diverse applications and biological relevance make it a subject of ongoing research interest.

Synonyms

4-methyl-1,2,5-oxadiazol-3-amine

3-Amino-4-methylfurazan

675-775-7

17647-70-0

1,2,5-Oxadiazol-3-amine, 4-methyl-

MFCD00186403

Furazanamine, 4-methyl-

4-Methylfurazanamine

F3334-0607

4-methyl-1,2,5-oxadiazole-3-ylamine

Furazan, aminomethyl-

3-Amino-4-metilfurazano [Italian]

3-Amino-4-metilfurazano

BRN 0109522

Furazan, aminomethyl- (8CI)

aminomethyl-furaza

FURAZAN, 3-AMINO-4-METHYL-

3-Amino-4-methyl-1,2,5-oxadiazole

4-Methyl-1,2,5-Oxadiazole-3-amine

4-methyl-3-aminofurazan

4-methyl-3-furazanylamine

4-27-00-08060 (Beilstein Handbook Reference)

SCHEMBL1458149

QIEJLLIYONRHBH-UHFFFAOYSA-

DTXSID80170139

SMSSF-0614494

ALBB-010469

SBB002777

STK743764

4-methyl-1,2,5-oxadiazol-3-ylamine

AKOS000112286

PB41270

4-methyl-1,2,5-oxadiazol-3-yl-amine

DA-09220

LS-03547

SY042593

ST4119449

CS-0044955

EN300-09557

F14552

AG-670/31544030

Z57948408

InChI=1/C3H5N3O/c1-2-3(4)6-7-5-2/h1H3,(H2,4,6)