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4-Methylphthalazin-1-one

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Identification
Molecular formula
C9H8N2O
CAS number
932-13-2
IUPAC name
4-methyl-2H-phthalazin-1-one
State
State

At room temperature, 4-Methylphthalazin-1-one is typically in a solid state, usually appearing as a crystalline or powder form. It is stable under ordinary conditions well-suited for handling and storage in typical chemical laboratories.

Melting point (Celsius)
196.00
Melting point (Kelvin)
469.00
Boiling point (Celsius)
254.00
Boiling point (Kelvin)
527.00
General information
Molecular weight
160.17g/mol
Molar mass
160.1710g/mol
Density
1.2870g/cm3
Appearence

4-Methylphthalazin-1-one generally appears as a crystalline solid with a white to off-white color. It is often used in various organic synthesis processes and might appear as powder form depending on the specific preparation method.

Comment on solubility

Solubility of 4-methyl-2H-phthalazin-1-one

4-methyl-2H-phthalazin-1-one, a member of the phthalazinone family, presents interesting solubility characteristics that can significantly influence its applications in various fields. Understanding its solubility profile is essential for its effective use in pharmaceutical and chemical processes.

Solubility Behavior

Here are some key points regarding the solubility of 4-methyl-2H-phthalazin-1-one:

  • Polar solvents: This compound exhibits reasonable solubility in polar solvents such as ethanol and dimethyl sulfoxide (DMSO), which suggests that the presence of polar functional groups contributes to intermolecular interactions.
  • Non-polar solvents: Conversely, it shows limited solubility in non-polar solvents like hexane and chloroform, indicating that hydrophobic interactions play a lesser role in its solubility.
  • Temperature dependency: The solubility may also vary with temperature; many compounds show increased solubility at elevated temperatures, making this an essential factor for practical applications.

In summary, the solubility of 4-methyl-2H-phthalazin-1-one is influenced by its molecular structure and environmental conditions. Understanding these nuances can enhance its utilization in research and industry. As always, "solubility is a gateway to applications," highlighting the need for thorough investigation in practical scenarios.

Interesting facts

Interesting Facts about 4-Methyl-2H-Phthalazin-1-One

4-Methyl-2H-phthalazin-1-one is a fascinating compound that belongs to the phthalazinone family, known for its unique structural attributes and diverse applications. Here are some intriguing aspects of this chemical:

  • Chemical Structure: The compound features a phthalazinone core, which is characterized by a fused bicyclic ring system consisting of a 1,2-diazine and a carbonyl group. This specific architecture makes it a valuable subject for various organic synthesis methods.
  • Biological Activity: Compounds in the phthalazinone category have demonstrated significant biological activities, including potential anticancer and anti-inflammatory properties. This opens up exciting avenues for pharmaceutical research and development.
  • Research Applications: Researchers often explore the chemical's reactivity for synthesizing analogs with enhanced properties, making it a compound of interest in medicinal chemistry.
  • Solubility Profiles: The solubility of 4-methyl-2H-phthalazin-1-one in different solvents can greatly influence its reaction pathways and potential applications in solving organic materials.
  • Analytical Techniques: Various spectroscopic methods like NMR and mass spectrometry are employed to elucidate the structure and confirm the purity of this compound, showcasing its significance in chemical analysis.

As quoted by renowned chemists, "The beauty of chemistry lies not only in the compounds but also in their transformations and applications." 4-Methyl-2H-phthalazin-1-one exemplifies this philosophy and continues to captivate the scientific community.

Synonyms
1-Hydroxy-4-methylphthalazine
828-285-4
4-Methylphthalazin-1(2H)-one
5004-48-8
4-Methyl-2H-phthalazin-1-one
4-METHYL-1(2H)-PHTHALAZINONE
Hydroxy-4-methylphthalazine
1(2H)-Phthalazinone, 4-methyl-
4-Methylphthalazin-1-ol
4-Methyl-1-phthalazinol
4-METHYL-1,2-DIHYDROPHTHALAZIN-1-ONE
MFCD00024098
NSC-116342
4-Methyl-1-phthalazinone
NSC116342
4-methylphthalazinone
NSC 116342
ICX-56274004
E8FX6PDG8U
1-Phthalazinol, 4-methyl-
MLS000777792
SCHEMBL555280
SCHEMBL8273098
CHEMBL1399916
DTXSID40198192
QRNVHFPDZAZUGX-UHFFFAOYSA-N
HMS1654L09
HMS1756E14
HMS2742N05
4-Methyl-(2H)-phthalazin-1-one
ALBB-024861
GEO-04153
STK877962
AKOS001049804
AKOS002212270
FH24263
MB00345
ICX56274004
NCGC00246355-01
AS-37954
SMR000414227
SY083782
CS-0067998
EN300-17094
4-Methyl-1-phthalazinol;4-Methyl-1-phthalazinone
AC-907/25004909
Z56877312
4-Methyl-1-phthalazinol;4-Methyl-1-phthalazinone;NSC 116342