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4-Methyl-3-nitrobenzoic acid

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Identification
Molecular formula
C8H7NO4
CAS number
4516-71-0
IUPAC name
4-methyl-3-nitro-benzoic acid
State
State

At room temperature, 4-Methyl-3-nitrobenzoic acid is a solid. It is stable under normal conditions but should be stored in a cool, dry place to prevent degradation. This compound is not volatile and therefore not commonly found in a gaseous state under standard conditions.

Melting point (Celsius)
169.40
Melting point (Kelvin)
442.55
Boiling point (Celsius)
353.80
Boiling point (Kelvin)
626.95
General information
Molecular weight
181.15g/mol
Molar mass
181.1500g/mol
Density
1.4284g/cm3
Appearence

4-Methyl-3-nitrobenzoic acid typically appears as a crystalline solid. It is usually yellow to light brown in color and has a faintly aromatic smell. The compound's crystals can vary in size depending on the conditions of crystallization.

Comment on solubility

Solubility of 4-methyl-3-nitro-benzoic acid

4-methyl-3-nitro-benzoic acid, with the chemical formula C8H9NO4, exhibits interesting solubility characteristics that merit attention.

  • Polar Characteristics: Due to the presence of both a nitro group (–NO2) and a carboxylic acid group (–COOH), this compound displays considerable polarity. This polarity tends to enhance its solubility in polar solvents.
  • Water Solubility: While organic acids generally have limited water solubility, 4-methyl-3-nitro-benzoic acid has moderate solubility in water, attributed to the ability of the carboxylic group to engage in hydrogen bonding with water molecules.
  • Solubility in Organic Solvents: The compound is more soluble in organic solvents such as ethanol, methanol, and acetone, where it can interact favorably through dipole-dipole interactions and van der Waals forces.
  • Temperature Dependence: Solubility can also be temperature-dependent; typically, increasing temperature improves solubility in many cases.

In summary, the solubility of 4-methyl-3-nitro-benzoic acid reflects its molecular structure and the functional groups present. Understanding its solubility is crucial for applications in organic synthesis and pharmaceutical formulations.

Interesting facts

Interesting Facts about 4-Methyl-3-Nitro-Benzoic Acid

4-Methyl-3-nitro-benzoic acid is a fascinating compound that finds its significance in both industrial applications and research. Here are some intriguing facts about this compound:

  • Structural Attributes: The compound features a benzoic acid structure with both methyl and nitro groups substituted on the aromatic ring. This unique arrangement makes it particularly interesting for organic synthesis.
  • Colloquial Name: Often referred to in academic and industrial settings as 4-Methyl-3-Nitrobenzoic Acid, its name reflects the positions of the substituents on the benzene ring.
  • Synthetic Applications: 4-Methyl-3-nitro-benzoic acid is utilized in the production of various azo dyes, which are important in the textile industry. These dyes are known for their vibrant colors and robustness.
  • Research Significance: This compound serves as a useful intermediate in the synthesis of pharmaceutical compounds, particularly in creating analgesics and anti-inflammatory agents.
  • Polar Properties: The presence of the nitro group introduces polarity into the molecule, affecting its reactivity and interactions in chemical processes.

Research has indicated that compounds with similar structures may also exhibit interesting biological activities, highlighting the compound's potential in drug development. As one quote from a noted chemist puts it, "The more we understand the subtleties of structural chemistry, the more possibilities for innovation we unveil." Hence, studying compounds like 4-methyl-3-nitro-benzoic acid not only broadens our knowledge but also enriches the field of organic chemistry.

Synonyms
4-Methyl-3-nitrobenzoic acid
96-98-0
3-Nitro-p-toluic acid
3-Nitro-4-methylbenzoic acid
Benzoic acid, 4-methyl-3-nitro-
3-Nitro-para-toluic acid
p-Toluic acid, 3-nitro-
m-Nitro-p-toluic acid
4-METHYL-3-NITRO-BENZOIC ACID
EINECS 202-549-3
4SVO2C6KJ2
MFCD00007174
NSC 50659
DTXSID6025642
NSC-50659
UNII-4SVO2C6KJ2
DTXCID705642
BBEWSMNRCUXQRF-UHFFFAOYSA-
EC 202-549-3
METHYL-3-NITROBENZOIC ACID, 4-
4-Methyl-3-nitrobenzoicacid
benzoic acid,4-methyl-3-nitro
3-NITRO-4-METHYL BENZOIC ACID
3-Nitro-4-methylbenzoic Acid; 3-Nitro-p-toluic Acid; NSC 50659
mNitroptoluic acid
3Nitroptoluic acid
NSC50659
3Nitroparatoluic acid
4-METHYL-3-NITRO BENZOIC ACID
pToluic acid, 3nitro
3Nitro4methylbenzoic acid
Benzoic acid, 4methyl3nitro
Oprea1_315455
MLS002152889
SCHEMBL177231
pToluic acid, 3nitro (8CI)
CHEMBL1488599
HMS3039P06
BCP24478
Tox21_201069
STK358776
4-Methyl-3-nitrobenzoic acid, 99%
AKOS000120551
AKOS023769640
AC-3037
FM02018
HY-W021293
CAS-96-98-0
BENZOIC ACID, 4-METHYL-3-NITRO
NCGC00091412-01
NCGC00091412-02
NCGC00258622-01
AS-11011
SMR001224501
DB-003966
CS-0039942
M0950
NS00008582
EN300-17977
AE-562/40723402
4-Methyl-3-nitrobenzoic acid;3-Nitro-p-toluic acid
Z57127401
F3095-3211
202-549-3