4-methyl-N-(2-morpholinoethyl)-6-phenyl-pyridazin-3-amine;dihydrochloride

Identification

Molecular formula

C₁₇H₂₃Cl₂N₅O

CAS number

28857-04-5

IUPAC name

4-methyl-N-(2-morpholinoethyl)-6-phenyl-pyridazin-3-amine;dihydrochloride

State

At room temperature, 4-methyl-N-(2-morpholinoethyl)-6-phenyl-pyridazin-3-amine;dihydrochloride is typically in a solid state, appearing as a crystalline powder.

Melting point (Celsius)

181.50

Melting point (Kelvin)

454.65

Boiling point (Celsius)

812.60

Boiling point (Kelvin)

1 085.75

General information

Molecular weight

409.37g/mol

Molar mass

409.3650g/mol

Density

1.3565g/cm³

Appearence

The compound is typically seen as a fine, crystalline powder. It may vary slightly in color but is generally white or off-white.

Comment on solubility

Solubility of 4-methyl-N-(2-morpholinoethyl)-6-phenyl-pyridazin-3-amine; dihydrochloride

The solubility of 4-methyl-N-(2-morpholinoethyl)-6-phenyl-pyridazin-3-amine; dihydrochloride is a significant factor influencing its pharmaceutical and chemical applications. Understanding the solubility characteristics of this compound can be summarized as follows:

Solvent Compatibility: This dihydrochloride salt typically exhibits solubility in aqueous solutions due to the presence of two chloride ions, which enhance its ionization and solubility.
Temperature Dependence: Like many ionic compounds, its solubility is likely to increase with temperature. Higher temperatures often provide greater kinetic energy, facilitating the dissolution process.
pH Influence: The solubility may also be influenced by the pH of the solution. In more acidic conditions, the protonation of the amine groups might enhance solubility further.
Crystal Form: The polymorphic nature of the compound can affect solubility; different crystalline forms may have different solubility profiles.

In conclusion, the solubility of 4-methyl-N-(2-morpholinoethyl)-6-phenyl-pyridazin-3-amine; dihydrochloride is a dynamic property that can be modulated by various factors such as solvent composition, temperature, pH, and crystal morphology. Understanding these aspects is crucial for effective formulation in various applications.

Interesting facts

Interesting Facts about 4-Methyl-N-(2-morpholinoethyl)-6-phenyl-pyridazin-3-amine Dihydrochloride

4-Methyl-N-(2-morpholinoethyl)-6-phenyl-pyridazin-3-amine dihydrochloride is a chemical compound that has gained attention in the field of medicinal chemistry. Here are some fascinating aspects of this compound:

Pharmacological Potential: This compound is part of the pyridazine family, which is known for its diverse biological activities, including anti-inflammatory and anticancer properties. As research progresses, compounds like this one may reveal new therapeutic avenues.
Structure-Activity Relationship: The unique structure of this molecule contributes to its binding affinity to various biological targets. Understanding the structure-activity relationship (SAR) can provide insights into how slight modifications might enhance its efficacy.
Morpholino Ring: The presence of the morpholino group indicates potential central nervous system (CNS) activity, as compounds with similar structures have been associated with improved ability to cross the blood-brain barrier.
Dual Action: Compounds in this class often exhibit dual therapeutic effects, which could be harnessed for combination therapies in treating diseases that require targeting multiple pathways.
Applications in Research: This compound is often used as a starting point for the development of new drugs. Its interactions with various biological molecules make it a valuable tool in pharmacological studies.

As we delve deeper into the research surrounding 4-methyl-N-(2-morpholinoethyl)-6-phenyl-pyridazin-3-amine dihydrochloride, who knows what groundbreaking discoveries await us?

Synonyms

Minaprine dihydrochloride

MINAPRINE HYDROCHLORIDE

Minaprine HCl

30038CB

82Y7NT6DFT

DTXSID2045864

NSC-305742

3-(2-Morpholinoethylamino)-4-methyl-6-phenylpyridazine dihydrochloride

30038-CB

DTXCID0025864

CHEBI:51040

N-(4-Methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine dihydrochloride

Morpholine, 4-(2-((4-methyl-6-phenyl-3-pyridazinyl)amino)ethyl)-, dihydrochloride

NSC305742

RefChem:158941

25953-17-7

Minaprine (dihydrochloride)

Minaprine hydrochloride [USAN]

AGR 620

MFCD00083410

4-methyl-N-(2-morpholinoethyl)-6-phenylpyridazin-3-amine dihydrochloride

4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine;dihydrochloride

4-Morpholineethanamine, N-(4-methyl-6-phenyl-3-pyridazinyl)-,dihydrochloride

Minaprine hydrochloride (USAN)

4-(2-((4-Methyl-6-phenyl-3-pyridazinyl)amino)ethyl)morpholine dihydrochloride

CAS-25953-17-7

UNII-82Y7NT6DFT

NSC 305742

CM 30038

C17H24Cl2N4O

Alcas

SR-01000003128

Minaprin diHCl

Prestwick_2

4-Morpholineethanamine, N-(4-methyl-6-phenyl-3-pyridazinyl)-, dihydrochloride

SCHEMBL124092

SPECTRUM1501120

orb1298537

CHEMBL1364551

HY-B0884A

GLXC-06141

HMS1568M13

HMS1921F21

HMS5085K09

HMS6018B07

Tox21_111355

CCG-39019

MINAPRINE HYDROCHLORIDE [JAN]

s5663

MINAPRINE DIHYDROCHLORIDE [MI]

AKOS030526122

Tox21_111355_1

30038CM

MINAPRINE HYDROCHLORIDE [MART.]

NCGC00016795-06

NCGC00016795-11

NCGC00094902-01

NCGC00094902-02

BM166417

DA-65468

FM158555

MINAPRINE DIHYDROCHLORIDE [WHO-DD]

MS-25973

Minaprine dihydrochloride, analytical standard

D05040

F85187

SR-01000003128-3

Q27122287

4-methyl-N-(2-morpholinoethyl)-6-phenyl-pyridazin-3-amine;dihydrochloride

4-MORPHOLINEETHANAMINE, N-(4-METHYL-6-PHENYL-3-PYRIDAZINYL)-, DIHYDROCHLORIDE (2) 4-(2-((4-METHYL-6-PHENYL-3-PYRIDAZINYL)AMINO)ETHYL)MORPHOLINE DIHYDROCHLORIDE.