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Tosylate

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Identification
Molecular formula
C20H28ClN3O4S2
CAS number
not available
IUPAC name
4-methyl-N-[3-[3-(p-tolylsulfonylamino)propylamino]propyl]benzenesulfonamide;hydrochloride
State
State

At room temperature, this compound is a solid and is typically stored in a desiccator to prevent absorption of moisture from the air. It is stable under normal laboratory conditions.

Melting point (Celsius)
154.00
Melting point (Kelvin)
427.15
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.15
General information
Molecular weight
473.04g/mol
Molar mass
473.0400g/mol
Density
1.2000g/cm3
Appearence

4-methyl-N-[3-[3-(p-tolylsulfonylamino)propylamino]propyl]benzenesulfonamide; hydrochloride appears as a white crystalline powder in its pure form. It is often used in laboratory settings and may appear slightly off-white if impurities are present.

Comment on solubility

Solubility of 4-methyl-N-[3-[3-(p-tolylsulfonylamino)propylamino]propyl]benzenesulfonamide;hydrochloride

The solubility of 4-methyl-N-[3-[3-(p-tolylsulfonylamino)propylamino]propyl]benzenesulfonamide; hydrochloride can be influenced by several factors, given its complex structure. Generally, compounds with sulfonamide functional groups, like this one, exhibit varying solubility in aqueous and organic solvents.

Key points regarding its solubility include:

  • Hydrochloride salt formation: The presence of the hydrochloride salt often enhances the solubility of the compound in water, as salts tend to be more soluble than their parent amine bases.
  • Polar functionality: The sulfonamide groups contribute significant polarity, which may lead to good solubility in polar solvents.
  • Influence of substituents: The methyl and p-tolyl groups can impact solubility by affecting sterics and hydrophobic interactions, which might reduce solubility in highly polar environments.

In conclusion, while the solubility of this compound in water is likely enhanced due to its hydrochloride form, organic solubility may vary, highlighting the importance of considering the entire molecular structure when predicting solubility. Furthermore, **experimental solubility tests** may be necessary to provide precise data for specific applications.

Interesting facts

Interesting Facts about 4-methyl-N-[3-[3-(p-tolylsulfonylamino)propylamino]propyl]benzenesulfonamide; hydrochloride

This compound, known for its complex structure, is an important member of the sulfonamide family, which has garnered significant attention in medicinal chemistry. The following facts highlight its relevance and applications:

  • Medicinal Applications: Sulfonamides are widely recognized for their antimicrobial properties. This specific compound, with its multifunctional design, potentially enhances therapeutic efficacy against various bacterial infections.
  • Structure-Activity Relationship: The presence of the methyl and sulfonylamino groups within the structure contributes to its biological activity. Understanding these relationships is crucial for drug design and development.
  • Research Interest: With ongoing research into optimizing similar compounds, the synthetic pathways and modifications of this particular compound stimulate curiosity and studies among chemists, particularly in areas related to cancer treatment and autoimmune diseases.
  • Inhibition Mechanism: This compound may act as an inhibitor of specific enzymes or receptors within the bacterial cell, which can disrupt their function and lead to cell death. Its mechanism of action is a focal point for many pharmacological investigations.
  • Potential Side Effects: As with many pharmaceuticals, understanding side effects and toxicity associated with this compound is crucial. Research continues to explore its safety profile—key insights for its use in clinical settings.

Quotes from leading researchers in medicinal chemistry often reflect the significance of compounds like this one: "Innovative compounds can lead to revolutionary treatments, bridging the gap between chemistry and effective patient care." It encompasses not only the chemistry but also the hope for curing diseases that have a significant impact on global health.

In summary, 4-methyl-N-[3-[3-(p-tolylsulfonylamino)propylamino]propyl]benzenesulfonamide; hydrochloride exemplifies how the intricate design of chemical compounds can pave the way for groundbreaking advancements in medicine.

Synonyms
N,N'-(Iminoditrimethylene)di-p-toluenesulfonamide
13380-01-3
DTXSID40158372
N,N'-(Iminodi-3,1-propanediyl)bis(4-methylbenzenesulfonamide)
DTXCID1080863
4-methyl-N-[3-[3-[(4-methylphenyl)sulfonylamino]propylamino]propyl]benzenesulfonamide;hydrochloride
Ro 5-5340