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9-Aminoacridine

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Identification
Molecular formula
C14H12N2
CAS number
90-45-9
IUPAC name
4-methylacridin-9-amine
State
State

At room temperature, 9-Aminoacridine is typically a solid. It is relatively stable under normal conditions, although it should be handled with care due to its chemical properties.

Melting point (Celsius)
227.00
Melting point (Kelvin)
500.15
Boiling point (Celsius)
299.00
Boiling point (Kelvin)
572.15
General information
Molecular weight
194.26g/mol
Molar mass
194.2440g/mol
Density
1.0550g/cm3
Appearence

9-Aminoacridine appears as an orange to yellow crystalline solid or powder. It is commonly used as a laboratory reagent and sometimes handled in its hydrochloric acid salt form, which is more stable.

Comment on solubility

Solubility of 4-methylacridin-9-amine

4-methylacridin-9-amine, a compound featuring both aromatic and amino functionalities, exhibits intriguing solubility characteristics that can be influenced by several factors, including temperature and solvent choice.

Solubility Characteristics:

  • Solvent Polarity: Generally, this compound is more soluble in polar aprotic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF) due to its capability to participate in hydrogen bonding.
  • Temperature Influence: Increased temperature typically enhances solubility, allowing for a greater dissolution rate in various solvents.
  • pH Sensitivity: The solubility can also be affected by the pH of the solution. Under acidic conditions, the amine group may become protonated, increasing its solubility in water.

It is important to note that the compound may exhibit limited solubility in non-polar solvents, such as hexane or chloroform, which do not favorably interact with the polar amine groups. Consequently, understanding the solubility of 4-methylacridin-9-amine is critical for its application in organic synthesis and pharmaceuticals, where solvent choice can significantly impact reaction efficiency.

Interesting facts

Interesting Facts about 4-methylacridin-9-amine

4-methylacridin-9-amine is a fascinating chemical compound that belongs to the acridine group, which is known for its diverse applications in various fields. Here are a few intriguing aspects of this compound:

  • Biomedical Applications: Compounds related to acridine are particularly interesting in the realm of pharmaceuticals. They often exhibit antimicrobial and anti-cancer properties. 4-methylacridin-9-amine has been studied for its potential roles in medicinal chemistry.
  • Fluorescent Properties: Like many acridine derivatives, 4-methylacridin-9-amine possesses inherent fluorescent properties, making it suitable for use in biological imaging and detection applications. This fluorescence can aid in visualizing cellular processes.
  • Research Significance: Research in the area of acridines has been ongoing for decades. The unique structure of 4-methylacridin-9-amine has sparked interest in theoretical studies, focusing on its electronic properties and chemical reactivity.
  • Unraveling Interactions: Scientists are particularly interested in studying how this compound interacts with biomolecules, providing insights into how it can modulate biological activities.

In summary, 4-methylacridin-9-amine is not just another chemical compound; it is a part of a larger narrative in the scientific community as researchers continue to explore its potential applications and contribute to the understanding of acridine derivatives. As one of the voices in this narrative might say: "Each compound has its story to tell, and sometimes it whispers secrets of healing and discovery."

Synonyms
Neomonacrin
Salacrin
Methylaminacrine
4-Methyl-9-acridinamine
9-Acridinamine, 4-methyl-
ACRIDINE, 9-AMINO-4-METHYL-
5-Amino-1-methylacridine (European)
BRN 0159958
DTXSID50188988
5-22-11-00076 (Beilstein Handbook Reference)
DTXCID10111479
9-Acridinamine, 4-methyl-(9CI)
3548-10-5
9-Amino-4-methylacridine
CHEMBL343190
SCHEMBL11060901
9-Acridinamine, 4-methyl- (9CI)