Interesting facts
Interesting Facts about 4-Methylaniline
4-Methylaniline, also commonly known as p-toluidine, is an organic compound that is significant in the realm of industrial chemistry and color science. With a structure defined by an amino group attached to the aromatic ring of toluene's methyl group, it presents several interesting attributes:
- Industrial Applications: 4-Methylaniline is widely used as an intermediate in the production of dyes, particularly azo dyes, which are vital in coloring textiles, plastics, and papers.
- Pharmaceutical Relevance: This compound plays a role in synthesizing pharmaceuticals, including various antihistamines and analgesics.
- Safety Considerations: While useful, 4-methylaniline must be handled with care, as it is considered toxic, and exposure can lead to adverse health effects. As such, proper safety protocols are essential in laboratory environments.
- Environmental Impact: Given its potential toxicity, 4-methylaniline is subject to environmental regulations to mitigate its impact on ecosystems when it is released.
Unique Characteristics
In the world of chemistry, 4-methylaniline is notable for:
- Basicity: The amino group –NH2 increases the basicity of the molecule, making it a nucleophile capable of participating in various chemical reactions.
- Detection in Analytical Chemistry: Its presence can be detected using techniques such as gas chromatography-mass spectrometry (GC-MS), showcasing its importance in forensic and environmental analysis.
- Research Interest: Ongoing research often explores its role in developing advanced materials and its function in organic synthesis techniques.
In summary, 4-methylaniline is much more than just a chemical formula. It offers a glimpse into the intersection of chemistry, industry, and safety, making it a compound worth studying for aspiring chemists and industry professionals alike.
Synonyms
p-Toluidine
4-Methylaniline
106-49-0
4-Toluidine
4-Methylbenzenamine
p-Tolylamine
4-AMINOTOLUENE
Benzenamine, 4-methyl-
p-Methylaniline
p-Toluidin
p-Aminotoluene
p-Methylbenzenamine
1-Amino-4-methylbenzene
Naphtol AS-KG
Naphtol AS-KGLL
para-toluidine
Aniline, p-methyl-
4-Aminotoluen
Toluidine, p-
4-Amino-1-methylbenzene
RCRA waste number U353
Tolylamine
p-Toluidyna
p-Toluidyna [Polish]
C.I. Azoic Coupling Component 107
NSC 15350
12221-03-3
CCRIS 598
AZOIC COUPLING COMPONENT 107
C.I. 37107
4methylaniline
26915-12-8
DTXSID6021872
HSDB 2044
4-tolylamine
UNII-I1D0KL7I4U
EINECS 203-403-1
Aniline, 4-methyl-
CHEBI:37825
AI3-19858
4-METHYLBENZAMINE
NSC-15350
P-TOLUIDINE [MI]
I1D0KL7I4U
CHEMBL58521
P-TOLUIDINE [USP-RS]
4-AMINOTOLUENE [HSDB]
DTXCID601872
EC 203-403-1
P-TOLUIDINE [USP IMPURITY]
MFCD00007906
p-Toluidyna (Polish)
4-methylphenylamine
AMINOBENZOIC ACID IMPURITY D [EP IMPURITY]
P-TOLUIDINE (USP-RS)
p-Toluidin [Czech]
4-Aminotoluen [Czech]
P-TOLUIDINE (USP IMPURITY)
CAS-106-49-0
CI Azoic Coupling Component 107
AMINOBENZOIC ACID IMPURITY D (EP IMPURITY)
4-Methyl-1-aminobenzene
RCRA waste no. U353
paratoluidine
pAminotoluene
pMethylaniline
pToluidyna
pTolylamine
CI 37107
pToluidin
Tolyamine
4Aminotoluene
4Aminotoluen
p-Tolyamine
4Toluidine
p-tolyl-amine
4-amino-toluene
Aniline, pmethyl
pMethylbenzenamine
Toluidine, p
para-methylaniline
4-methyl aniline
4-methyl-aniline
4Methylbenzenamine
Naphtol ASKG
Naphtol ASKGLL
4MN
p-Methylbenzeneamine
1Amino4methylbenzene
4Amino1methylbenzene
4-methyl-phenylamine
Benzenamine, 4methyl
p-Toluidine, 99%
section signa-Touidine
Benzamine, 4-methyl-
p-Toluidine (ACGIH)
Benzolamin, 4-methyl-
1-Amino-4-methylbenzol
p-Toluidine, 99.6%
4-METHYLBENZENEAMINE
WLN: ZR D1
SCHEMBL11887
p-Toluidine, liquid or solid
Benzenamine, 4-methyl-(9CI)
p-Toluidine, for synthesis, 99%
C.I.Azoic Coupling Component 107
NSC15350
Tox21_202142
Tox21_300168
BDBM50008562
STL137776
AKOS000119134
GS-6708
p-Toluidine 100 microg/mL in Methanol
NCGC00247917-01
NCGC00247917-02
NCGC00247917-03
NCGC00254002-01
NCGC00259691-01
BP-11946
DB-024354
NS00003075
p-Toluidine, SAJ special grade, >=99.0%
T0300
EN300-17941
p-Toluidine, liquid or solid [UN1708] [Poison]
Q2043499
Z57127875
F2190-0420
P-TOLUIDINE, United States Pharmacopeia (USP) Reference Standard
p-Toluidine, for spectrophotometric det. of Au, Tl(III), W, >=99.0%
Solubility of 4-Methylaniline
4-methylaniline, also known as p-toluidine, is an organic compound with unique solubility characteristics in various solvents. Here are some key points regarding its solubility:
Overall, the solubility profile of 4-methylaniline showcases the influence of molecular structure on its interactions with different solvents. As one emphasizes, "the solubility is not solely dependent on polarity, but on structural nuances." Its applicability across various solvents highlights its versatility in both laboratory and industrial settings.