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4-Methylbenzenesulfonic acid

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Identification
Molecular formula
C7H8O3S
CAS number
104-15-4
IUPAC name
4-methylbenzenesulfonic acid;3-(2-sulfanylethylamino)propanamide
State
State

At room temperature, 4-methylbenzenesulfonic acid is typically found in a solid state.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.15
Boiling point (Celsius)
352.00
Boiling point (Kelvin)
625.15
General information
Molecular weight
172.21g/mol
Molar mass
172.2080g/mol
Density
1.2400g/cm3
Appearence

4-Methylbenzenesulfonic acid appears as a white crystalline solid. It is commonly utilized in organic synthesis and industrial applications.

Comment on solubility

Solubility of 4-methylbenzenesulfonic acid and 3-(2-sulfanylethylamino)propanamide

When analyzing the solubility of the compounds 4-methylbenzenesulfonic acid and 3-(2-sulfanylethylamino)propanamide, several factors must be considered, including their molecular structure and polarity.

4-methylbenzenesulfonic acid

4-methylbenzenesulfonic acid (also known as p-toluenesulfonic acid) is a sulfonic acid that is highly soluble in water. Key points about its solubility include:

  • Polarity: The sulfonic acid group (-SO3H) contributes to its high polarity.
  • Hydrogen bonding: Can form hydrogen bonds with water molecules, enhancing solubility.
  • Common uses: Often utilized as a catalyst and an acid in organic reactions due to its solubility.

As a result, this compound is generally very soluble in organic solvents and can dissolve in aqueous solutions effectively.

3-(2-sulfanylethylamino)propanamide

The solubility of 3-(2-sulfanylethylamino)propanamide is less straightforward and can vary depending on environmental conditions.

  • Hydrophilicity: The presence of the amine group (-NH2) may suggest potential solubility in water.
  • Thiol influence: The sulfanyl (thio) functionality can impact solubility, possibly increasing interaction with polar solvents.
  • Overall solubility: May show good solubility in polar organic solvents but variable behavior in water.

Hence, testing in specific environments is crucial to determine the precise solubility characteristics of this compound.

Interesting facts

Exploring 4-Methylbenzenesulfonic Acid

4-Methylbenzenesulfonic acid, commonly referred to as p-toluenesulfonic acid, is a fascinating compound widely used in organic synthesis. Here are some key points that highlight its significance:

  • Versatility in Reactions: This compound serves as an excellent acid catalyst, facilitating various reactions such as esterifications and alkylations.
  • Utility in Organic Chemistry: As a strong acid, it can replace sulfuric acid in many applications without the formation of unwanted side products.
  • Industrial Relevance: It's utilized in the manufacture of pharmaceuticals, dyes, and surfactants, showcasing its impact on diverse industries.
  • Safety Considerations: Due to its acidic nature, handling p-toluenesulfonic acid requires precautionary measures, including personal protective equipment.

In essence, p-toluenesulfonic acid is a crucial component in simplifying complex chemical processes, enabling scientists to innovate and explore new synthetic routes.


Diving into 3-(2-Sulfanylethylamino)propanamide

3-(2-Sulfanylethylamino)propanamide is an intriguing compound with applications that merit further exploration. Here are some insightful aspects:

  • Functional Groups: This compound contains both an amine and a thiol functional group, making it not only reactive but also an interesting subject for studies in medicinal chemistry.
  • Potential Biological Activity: Compounds featuring sulfur-containing moieties often exhibit significant biological activities, thus indicating potential as pharmaceutical agents.
  • Synthesis Challenges: The synthesis of this compound can pose challenges due to the need for selective reactions and protection of functional groups.
  • Research Interest: Scientists are continuously investigating compounds like this for their role in drug development, particularly in targeting specific biological pathways.

Overall, 3-(2-sulfanylethylamino)propanamide exemplifies the intersection of organic synthesis and medicinal chemistry, inviting excitement for future discoveries in pharmaceuticals.

Synonyms
1030-84-8
WR 2529
WBX2Y30M92
3-(2-Mercaptoethyl)aminopropionamide tosylate
NSC-124606
WR-2529
UNII-WBX2Y30M92
3-((2-Mercaptoethyl)amino)propanamide mono(4-methylbenzenesulfonate) (salt)
NSC 124606
PROPANAMIDE, 3-((2-MERCAPTOETHYL)AMINO)-, 4-METHYLBENZENESULFONATE (1:1)
beta-mercaptoethylaminopropionamide toluenesulfonic acid
propanamide, 3-((2-mercaptoethyl)amino)-, 4-methylbenzenesulfonate (salt)
unii-nc9iey3lg6
Propanamide, 3-((2-mercaptoethyl)amino)-, mono(4-methylbenzenesulfonate) (salt)
Propionamide, 3-((2-mercaptoethyl)amino)-, mono-p-toluenesulfonate (salt)
SCHEMBL789347
3-(2-Mercaptoethylamino)propionamide p-toluenesulofnate
DTXSID00908153
NSC124606
Propoamide, mono-p-tolunesulfonate (salt)
Propanamide, mono(4-methylbenzenesulfonate) (salt)
3-((2-mercaptoethyl)amino)propanamide 4-methylbenzenesulfonate
3-[(2-Sulfanylethyl)amino]propanimidic acid--4-methylbenzene-1-sulfonic acid (1/1)