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4-(Morpholinomethyl)morpholine

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Identification
Molecular formula
C9H18N2O2
CAS number
5625-90-1
IUPAC name
4-(morpholinomethyl)morpholine
State
State

At room temperature, 4-(Morpholinomethyl)morpholine is in a liquid state. It is generally stable under recommended storage conditions and is hygroscopic, meaning it can absorb moisture from the air.

Melting point (Celsius)
-55.00
Melting point (Kelvin)
218.15
Boiling point (Celsius)
247.00
Boiling point (Kelvin)
520.15
General information
Molecular weight
172.25g/mol
Molar mass
172.2460g/mol
Density
1.1181g/cm3
Appearence

The compound is typically a colorless to pale yellow liquid. It may appear as a clear and viscous substance, depending on its purity. It is likely to be uniform in appearance and free from any suspended particles.

Comment on solubility

Solubility of 4-(morpholinomethyl)morpholine

4-(morpholinomethyl)morpholine is a compound that exhibits interesting solubility properties. As a morpholine derivative, its solubility can be influenced by its functional groups and molecular structure. Here are some notable aspects:

  • Water Solubility: This compound shows a tendency to be highly soluble in water due to the presence of the morpholine ring and the ability to form hydrogen bonds with water molecules.
  • Organic Solvents: It is also soluble in a range of organic solvents, including ethanol and methanol, which makes it versatile for various applications in organic synthesis.
  • Effect of pH: The solubility can be affected by the pH of the solution; in acidic or basic conditions, the ionization of the amine groups may enhance solubility.

In summary, 4-(morpholinomethyl)morpholine is notable for its good solubility in polar solvents, which is primarily due to its ability to interact favorably with water and other solvents through hydrogen bonding and dipole-dipole interactions.

Interesting facts

Interesting Facts about 4-(Morpholinomethyl)morpholine

4-(Morpholinomethyl)morpholine is a fascinating compound in the realm of chemical research and applications. Known for its unique structural attributes, this compound features two morpholine rings connected by a methylene group, making it a member of the morpholine family.

Applications and Significance

  • Pharmaceutical Intermediates: This compound often serves as a building block in the synthesis of various pharmaceuticals, particularly in the development of drugs that target neurological disorders.
  • Polymer Chemistry: Its chemical structure allows it to be used in producing specialized polymers with desirable properties.
  • Biological Activity: Compounds with morpholine groups are frequently studied for their antibacterial and antifungal properties, highlighting the potential of 4-(morpholinomethyl)morpholine in medicinal chemistry.

Chemical Properties

This compound is notable for its stability and reactivity, making it a versatile candidate for numerous chemical reactions. Some of the key properties include:

  • Nucleophilicity: The nitrogen atoms in the morpholine rings provide nucleophilic sites that facilitate engaging in further chemical transformations.
  • Solubility: Its solubility in both polar and non-polar solvents makes it an excellent choice for a range of chemical processes.

Research and Innovations

Ongoing research is consistently unveiling new potential applications for 4-(morpholinomethyl)morpholine. As scientists continue to explore its interactions at the molecular level, new findings could lead to:

  • Enhanced Drug Design: Innovations in drug formulation that could improve therapeutic efficacy.
  • Novel Material Development: Creation of novel materials with enhanced mechanical and thermal properties.

In summary, 4-(morpholinomethyl)morpholine stands out as a compound of interest due to its diverse applications, unique chemical properties, and the ongoing potential for research and development. As the field of chemistry continues to evolve, so too will the significant roles of compounds like this one in pharmaceuticals, materials science, and beyond.

Synonyms
Dimorpholinomethane
Morpholine, 4,4'-methylenebis-
N,N'-Methylenebismorpholine
4,4'-Methylenebismorpholine
methylenebismorpholine
7O79DZW79Z
bis(morpholino)methane
4,4'-METHYLENEBIS(MORPHOLINE)
227-062-3
N,N'-Dimorpholinomethane
5625-90-1
4,4'-Methylenedimorpholine
4-(morpholin-4-ylmethyl)morpholine
4,4-Methylenedimorpholine
bis(4-morpholinyl)methane
MFCD00023369
4-[(morpholin-4-yl)methyl]morpholine
MORPHOLINE, 4,4'-METHYLENEDI-
Bismorpholino methane
n,n'-methylene-bis-morpholine
Bis(morpholino-)methan [German]
Bis(morpholino-)methan
EINECS 227-062-3
BRN 0111886
UNII-7O79DZW79Z
AI3-62944
bismorpholinomethane
Contram ST-1
N,N\'-Dimorpholinomethane
4,4-methylene-bismorpholine
Oprea1_332757
4,4'-methanediyldimorpholine
4-27-00-00203 (Beilstein Handbook Reference)
SCHEMBL536772
DTXSID8052859
FAA62590
AKOS002314380
FS-4049
AC-12628
SY032818
DB-052882
CS-0236719
NS00008963
EN300-172423
G77474
Q865946
F2163-0188