4-Nitro-3-(trifluoromethyl)phenol | Solubility of Things

Identification

Molecular formula

C₇H₄F₃NO₃

CAS number

13007-85-7

IUPAC name

4-nitro-3-(trifluoromethyl)phenol

State

At room temperature, 4-Nitro-3-(trifluoromethyl)phenol is found in a solid state. It maintains structural integrity as a crystalline solid unless subjected to temperatures above its melting point.

Melting point (Celsius)

90.00

Melting point (Kelvin)

363.15

Boiling point (Celsius)

289.00

Boiling point (Kelvin)

562.15

General information

Molecular weight

207.11g/mol

Molar mass

207.1240g/mol

Density

1.5650g/cm³

Appearence

4-Nitro-3-(trifluoromethyl)phenol appears as a yellow crystalline solid. The compound may exhibit characteristic phenolic odor and has relatively high density compared to water. It is visually distinct with a bright yellow color that is typical for nitro phenols.

Comment on solubility

Solubility of 4-nitro-3-(trifluoromethyl)phenol

4-nitro-3-(trifluoromethyl)phenol, with its complex structure, presents a unique profile in terms of solubility. Here are some key points to consider:

Polar vs. Non-Polar: The presence of both a nitro group and a trifluoromethyl group makes this compound somewhat polar, which may impact its solubility in various solvents.
Solvent Compatibility: Generally, compounds like 4-nitro-3-(trifluoromethyl)phenol are more soluble in polar solvents such as water and alcohols, but the extent of solubility can vary:

High Solubility: In polar aprotic solvents.
Low Solubility: In non-polar solvents due to hydrophobic interactions.

Hydrogen Bonding: The hydroxyl (-OH) group may form hydrogen bonds with solvent molecules, potentially enhancing solubility in water.
Temperature Dependency: As with many organic compounds, solubility can increase with temperature, allowing for more significant interaction with the solvent.

In summary, the solubility of 4-nitro-3-(trifluoromethyl)phenol is influenced by its molecular structure, solvent type, and temperature. It is best described as moderately soluble in polar solvents, highlighting the intricate relationship between molecular composition and solubility behavior.

Interesting facts

Interesting Facts about 4-nitro-3-(trifluoromethyl)phenol

4-nitro-3-(trifluoromethyl)phenol, also known as a notable member of the nitrophenol family, possesses intriguing characteristics that make it an important compound in both industrial and research applications. Here are some fascinating insights:

Functional Versatility: This compound exhibits both nitration and trifluoromethyl functionalities, which allow it to participate in a variety of chemical reactions. These traits can be exploited in organic synthesis, particularly in the production of agrochemicals and pharmaceuticals.
Biological Activity: The presence of the nitro group confers a level of biological activity that could be leveraged in medicinal chemistry, making this compound a potential candidate for research into drug development.
Environmental Considerations: Similar to other halogenated compounds, the trifluoromethyl group enhances lipophilicity, which raises concerns regarding its environmental impact, particularly its persistence and bioaccumulation.
Material Science Applications: The unique structural properties of 4-nitro-3-(trifluoromethyl)phenol make it an interesting candidate for the development of advanced materials, including coatings and polymers that require chemical stability and resistance to degradation.

As scientists continue to explore the properties and potential applications of this compound, its relevance in both environmental and health-related fields cannot be understated. Understanding the chemical behavior and reactive pathways of 4-nitro-3-(trifluoromethyl)phenol is essential for harnessing its full potential while navigating the challenges it presents.

Synonyms

4-Nitro-3-(trifluoromethyl)phenol

88-30-2

Lamprecide

5-Hydroxy-2-nitrobenzotrifluoride

Lamprecid

3-TRIFLUOROMETHYL-4-NITROPHENOL

Dowlap F

Phenol, 4-nitro-3-(trifluoromethyl)-

USAF MA-6

4-Nitro-3-trifluoromethylphenol

Caswell No. 890

TFM

Phenol, m-trifluoromethyl-

NSC 59758

tfm (piscicide)

3-(Trifluoromethyl)-4-nitrophenol

EINECS 201-818-2

alpha,alpha,alpha-Trifluoro-4-nitro-m-cresol

MFCD00014714

EPA Pesticide Chemical Code 036201

BRN 2053698

96W52A3IFS

DTXSID7021788

AI3-26208

HSDB 7506

m-Cresol, 4-nitro-alpha,alpha,alpha-trifluoro-

NSC-59758

DTXCID101788

TMF

m-Cresol, alpha,alpha,alpha-trifluoro-4-nitro-

3-06-00-01328 (Beilstein Handbook Reference)

HOE-2770

TRIFLUOROMETHYL-4-NITROPHENOL, 3-

4-NITRO-3-TRIFLUOROMETHYLPHENOL [HSDB]

UNII-96W52A3IFS

TFM (3-trifluoromethyl-4-nitrophenol)

WLN: WNR DQ BXFFF

3Trifluoromethyl4nitrophenol

TFM [MI]

SCHEMBL213627

CHEMBL1878174

2-nitro-5-hydroxybenzotrifluoride

3-Trifluoromethyl-4-nitro-phenol

4-nitro-3-trifluoromethyl phenol

Phenol, 4nitro3(trifluoromethyl)

NSC59758

?,?,?-trifluoro-4-nitro-m-cresol

4-nitro-3-(trifluoromethyl)-phenol

Tox21_300905

AKOS015890067

AKOS040755948

Phenol, m-trifluoromethyl-, p-nitro-

2-trifiuoromethyl-4-hydroxynitrobenzene

AC-3816

CS-W015282

FN64441

HY-W014566

CAS-88-30-2

USEPA/OPP Pesticide Code: 036201

mCresol, 4nitroalpha,alpha,alphatrifluoro

NCGC00164224-01

NCGC00164224-02

NCGC00254809-01

AS-33043

SY029610

1-Nitro-4-hydroxy-2-trifluromethylbenzene

1-Nitro-4-hydroxy-2-trifluoromethylbenzene

DB-057055

.alpha.,.alpha.-Trifluoro-4-nitro-m-cresol

alpha-alpha-alpha-trifluoro-4-nitro-m-cresol

N0279

NS00003239

1-Nitro-4-hydroxy-2-(trifluoromethyl)benzene

m-Cresol,.alpha.,.alpha.-trifluoro-4-nitro-

4-Nitro-3-(trifluoromethyl)phenol, 99% (GC)

.alpha.,.alpha.,.alpha.-Trifluoro-4-nitro-m-cresol

Q10860679

m-Cresol, .alpha.,.alpha.,.alpha.-trifluoro-4-nitro-

m-Cresol, 4-nitro-.alpha.,.alpha.,.alpha.-trifluoro-