Interesting facts
Interesting Facts about 4-Nitrobenzenesulfonyl Chloride
4-Nitrobenzenesulfonyl chloride is a fascinating compound that plays a significant role in various fields of chemistry, particularly in synthetic organic chemistry. Here are some intriguing aspects of this compound:
- Versatile Reagent: This compound is widely used as a sulfonylating agent, facilitating the introduction of the –SO2Cl group into organic molecules. This transformation is crucial in diverse chemical syntheses.
- Application in Drug Development: Due to its ability to modify amines and phenols, 4-nitrobenzenesulfonyl chloride is often employed in the development of pharmaceuticals, contributing to the creation of biologically active compounds.
- Role in Assays: In biochemistry, it is used to create sulfonamide derivatives, which can be valuable for developing assays and studying enzyme activities.
- Environmental Considerations: When handling this compound, it is essential to consider its environmental impact and adhere to safety protocols due to its reactivity and potential effects.
As noted by many chemists, "the power of sulfonyl chlorides in organic transformations is unparalleled." Researchers constantly explore new methods and reactions involving 4-nitrobenzenesulfonyl chloride. Its presence in laboratories signifies the intersection of innovation and the fundamental principles of chemistry.
In summary, 4-nitrobenzenesulfonyl chloride is not just a chemical; it is a vital tool that bridges the gap between theoretical knowledge and practical application in the realm of organic synthesis.
Synonyms
4-Nitrobenzenesulfonyl chloride
98-74-8
Benzenesulfonyl chloride, 4-nitro-
4-Nitrobenzenesulphonyl chloride
4-nitrobenzene-1-sulfonyl chloride
4-Nitrobenzenesulfonylchloride
4-Nitrophenylsulfonyl chloride
P-NITROBENZENESULFONYL CHLORIDE
p-Nitrophenylsulfonyl chloride
4-nitrobenzenesulphonylchloride
Benzenesulfonyl chloride, p-nitro-
4-Nitrobenzenesulfonic acid chloride
4-nitro-benzenesulfonyl chloride
NSC 13065
p-nitrobenzenesulphonyl chloride
AI3-52248
EINECS 202-697-9
MFCD00007445
4-nitrobenzene sulfonylchloride
DTXSID4059178
JXRGUPLJCCDGKG-UHFFFAOYSA-
NSC-13065
nosylchloride
Nosyl chloride
4-nitrobenzene sulfonyl chloride
NBSO2Cl
ZU5JD6BHB3
4-nitrophenylsulfonylchloride
4nitrophenylsulfonyl chloride
pNitrophenylsulfonyl chloride
p-Nitrobenzenesulfonylchloride
pNitrobenzenesulfonyl chloride
SCHEMBL17673
p-nitrobenzensulfonyl chloride
4-nitrobenzensulfonyl chloride
p-nitrobenzenesulphonylchloride
4nitrobenzenesulphonyl chloride
4-nitrophenylsulphonyl chloride
p-nitrophenyl-sulfonyl chloride
4-Nitrobenzenesulfanyl chloride
4-nitrophenyl sulfonyl chloride
p-nitro benzenesulfonyl chloride
Benzenesulfonyl chloride, pnitro
4-nitro benzenesulfonyl chloride
4-nitro-phenylsulphonyl chloride
4-nitrobenzene-sulfonyl chloride
Benzenesulfonyl chloride, 4nitro
CHEMBL4753649
DTXCID1049061
4-nitrobenzene sulphonyl chloride
p-nitro benzene sulfonyl chloride
p-Nitrobenzene sulphonyl chloride
4-nitro-benzene sulfonyl chloride
NSC9572
NSC-9572
NSC13065
4-nitrobenzenesulphonic acid chloride
BBL019758
STK538935
4-Nitrobenzenesulfonyl chloride, 97%
AKOS000119257
FN03618
Benzenesulfonyl chloride, pnitro (8CI)
UPCMLD0ENAT5685873:001
Benzenesulfonyl chloride, p-nitro-(8CI)
AS-14329
DB-032000
N0144
NS00022920
EN300-19034
C93521
4-Nitrobenzenesulfonyl chloride, technical grade, 90%
F9995-0064
Z104472298
202-697-9
Solubility of 4-Nitrobenzenesulfonyl Chloride
The solubility of 4-nitrobenzenesulfonyl chloride (C6H4ClNO3S) showcases some intriguing characteristics due to its chemical structure.
Solvent Compatibility
This compound is known to be:
Factors Influencing Solubility
The solubility of 4-nitrobenzenesulfonyl chloride can be attributed to factors including:
"Like dissolves like" is a fundamental rule in chemistry, indicating that polar compounds are more likely to dissolve in polar solvents, while non-polar compounds dissolve well in non-polar solvents. For instance, the affinity of 4-nitrobenzenesulfonyl chloride for non-polar organic solvents is significant, while its limited solubility in water suggests a lesser extent of interaction with polar molecules.
In practical applications, understanding the solubility of this compound is essential for optimizing reaction conditions and ensuring effective use in synthetic processes.