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4-nitrobutanamide

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Identification
Molecular formula
C4H8N2O3
CAS number
78000-42-9
IUPAC name
4-nitrobutanamide
State
State

4-Nitrobutanamide is typically found in a solid crystalline form at room temperature.

Melting point (Celsius)
62.00
Melting point (Kelvin)
335.15
Boiling point (Celsius)
264.90
Boiling point (Kelvin)
538.05
General information
Molecular weight
132.12g/mol
Molar mass
132.1210g/mol
Density
1.1890g/cm3
Appearence

4-Nitrobutanamide appears as a white to off-white crystalline solid. Its appearance can be described as powdery or granular, depending on the specific sample and method of preparation.

Comment on solubility

Solubility of 4-nitrobutanamide

4-nitrobutanamide, with the chemical formula C4H8N2O2, displays interesting solubility characteristics that are worth noting. This compound is typically known to be:

  • Soluble in water: 4-nitrobutanamide can dissolve in water to a certain degree, which is largely attributed to its polar amide functional group. The presence of the nitro group (–NO2) enhances its ability to interact with water molecules.
  • Soluble in organic solvents: It shows good solubility in various organic solvents such as ethanol and methanol, making it versatile in organic synthesis.
  • Temperature influenced: The solubility can also vary with temperature; higher temperatures generally increase solubility due to greater molecular movement.

It is important to recognize that the solubility behavior of 4-nitrobutanamide may differ based on the specific conditions of the solution. As stated, "Like dissolves like", meaning that the polar characteristics of this compound favor its dissolution in similarly polar solvents.

In summary, understanding the solubility of 4-nitrobutanamide is crucial for its practical applications in both laboratory settings and industrial processes.

Interesting facts

Interesting Facts about 4-Nitrobutanamide

4-Nitrobutanamide is a fascinating compound that occupies a unique position in the realm of organic chemistry. Here are some noteworthy aspects:

  • Functional Group: This compound features an amide functional group, which is critical in the formation of proteins and can serve as a versatile scaffold in medicinal chemistry. Amides are known for their stability and are often involved in various biological processes.
  • Applications in Research: Researchers often utilize 4-nitrobutanamide as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its nitro group can act as a valuable handle for further chemical modifications, allowing for the design of compounds with different biological activities.
  • Toxicity Considerations: Like many nitro compounds, 4-nitrobutanamide should be handled with care. The nitro group can be reduced to amines in biological systems, which may lead to distinct biological effects, emphasizing the importance of understanding its behavior in vivo.
  • Identity in Nature: Nitrogen-containing compounds, such as 4-nitrobutanamide, play crucial roles in nature, participating in various biochemical pathways. The adaptability of its structure allows it to mimic natural compounds, making it an interesting subject for studying metabolic pathways.
  • Research Frontiers: Scientists are keenly interested in exploring derivatives of 4-nitrobutanamide to develop new materials and pharmaceuticals. The exploration of its properties and applications continues to open avenues for innovation in multiple fields.

"Understanding compounds like 4-nitrobutanamide exemplifies the interplay between organic chemistry and practical applications, driving forward research that can significantly impact health and technology."

In summary, 4-nitrobutanamide stands as a prime example of how a simple chemical structure can lead to complex interactions and a wealth of knowledge in both academic and industrial contexts. Its journey from the lab to potential real-world applications makes it a compound worth studying!

Synonyms
4-nitrobutanamide
15473-27-5
BUTYRAMIDE, 4-NITRO-
BRN 1858810
EINECS 239-492-9
E30GVZ0180
UNII-E30GVZ0180
DTXSID00165709
DTXCID0088200
239-492-9
4-Nitrobutyramide
4-Nitro-Butyramide
SCHEMBL530227
QAA47327
MFCD01737115
AKOS006277678
BP-11991
BS-27698
NS00025024
EN300-1661110