Skip to main content

4-nitroisothiazole

ADVERTISEMENT
Identification
Molecular formula
C3H2N2O2S
CAS number
19010-66-3
IUPAC name
4-nitroisothiazole
State
State

4-Nitroisothiazole is typically a solid at room temperature.

Melting point (Celsius)
48.00
Melting point (Kelvin)
321.00
Boiling point (Celsius)
231.00
Boiling point (Kelvin)
504.00
General information
Molecular weight
144.13g/mol
Molar mass
144.1260g/mol
Density
1.6107g/cm3
Appearence

4-Nitroisothiazole appears as a yellow to orange crystalline solid. It is typically used in research settings and may have an odor characteristic of nitro compounds.

Comment on solubility

Solubility of 4-Nitroisothiazole

4-nitroisothiazole, with the chemical formula C4H3N3O2S, exhibits interesting solubility properties that are important for its applications in organic synthesis and chemical research. Understanding its solubility behavior can provide insight into its reactivity and potential interactions with other compounds.

Solubility Characteristics

The solubility of 4-nitroisothiazole can be summarized as follows:

  • In Water: 4-nitroisothiazole has limited solubility in water due to its relatively non-polar structure and the presence of the nitro group, which can create steric hindrance.
  • In Organic Solvents: It is more readily soluble in organic solvents such as acetone, ethanol, and dimethyl sulfoxide (DMSO) due to its lipophilic nature.
  • Temperature Effects: As with many organic compounds, solubility may increase with temperature, making it beneficial to consider heating when attempting to dissolve this compound in solvents.

In summary, the solubility of 4-nitroisothiazole emphasizes its dual nature of being more compatible with organic environments than with polar solvents like water. This characteristic is essential for researchers when selecting solvents for various applications, ensuring successful reactions and compound interactions.

Interesting facts

Interesting Facts About 4-Nitroisothiazole

4-Nitroisothiazole is a fascinating compound that finds its relevance across various fields, particularly in the realm of chemistry and pharmacology. Here are some intriguing aspects worth noting:

  • Unique Structure: The compound contains an isothiazole ring, which is known for its five-membered heterocyclic structure. The presence of both nitrogen and sulfur atoms within the ring contributes to its distinctive chemical behavior and reactivity.
  • Versatile Reactivity: 4-Nitroisothiazole is a notable intermediate in organic synthesis. Its ability to undergo various reactions makes it useful in creating more complex molecules. For example, it can participate in nucleophilic substitutions and can be further modified to yield derivatives for research purposes.
  • Biological Activity: Research has shown that compounds similar to 4-nitroisothiazole exhibit significant biological activity. They have been studied for their potential as antibacterial and antifungal agents, which underscores the importance of such derivatives in the development of new medicinal compounds.
  • Applications in Materials Science: Beyond biological uses, 4-nitroisothiazole can play a role in materials science. Its derivatives are being explored for use in the development of polymers and other materials where specific chemical properties are desired.
  • Analytical Techniques: The study of 4-nitroisothiazole often employs sophisticated analytical techniques such as NMR (nuclear magnetic resonance) and mass spectrometry. These techniques enable chemists to unambiguously determine its structure and confirm the products formed in chemical reactions.

In conclusion, 4-nitroisothiazole exemplifies a compound rich in potential and versatility. Its unique properties and applications across various scientific domains continue to inspire research and innovation in chemistry.

Synonyms
4-Nitroisothiazole
ISOTHIAZOLE, 4-NITRO-
BRN 0907283
DTXSID70239264
DTXCID90161755
fnxpayvhlsthqy-uhfffaoysa-n
4-Nitro-isothiazole
931-07-7
4-nitro-1,2-thiazole
MFCD01716903
SCHEMBL10398917
AAA93107
AKOS006276225
AS-38169
SY147649
CS-0095615
EN300-120959