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Chelidonic acid

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Identification
Molecular formula
C7H4NO5
CAS number
99-32-1
IUPAC name
4-oxo-1H-pyridine-2,6-dicarboxylic acid
State
State

At room temperature, chelidonic acid is in a solid state. It is typically handled as a crystalline powder in ambient conditions. It remains stable and does not show a tendency to rapidly decompose or evaporate under normal conditions.

Melting point (Celsius)
251.00
Melting point (Kelvin)
524.00
Boiling point (Celsius)
570.00
Boiling point (Kelvin)
843.00
General information
Molecular weight
195.11g/mol
Molar mass
196.1210g/mol
Density
1.8070g/cm3
Appearence

Chelidonic acid typically appears as a white or off-white crystalline powder. It can exist in a solid form at room temperature and is known for its ability to dissolve in water, creating a clear solution. Its crystalline nature makes it identifiable by its structured, solid-state appearance.

Comment on solubility

Solubility of 4-oxo-1H-pyridine-2,6-dicarboxylic acid

The solubility of 4-oxo-1H-pyridine-2,6-dicarboxylic acid is an interesting topic worth exploring. This compound, often referred to as a derivative of pyridine, features two carboxylic acid groups, which significantly influence its solubility properties.

Factors Influencing Solubility

Several factors play a crucial role in determining the solubility of this compound:

  • Polarity: The presence of two carboxylic acid groups enhances the polarity of the molecule, making it more likely to dissolve in polar solvents like water.
  • Hydrogen Bonding: These carboxylic groups can form hydrogen bonds with water molecules, further increasing solubility.
  • pH Dependency: The solubility may also depend on the pH of the solution, as the carboxylic acid groups can exist in protonated or deprotonated forms.

Expected Solubility

In general:

  • Water Solubility: 4-oxo-1H-pyridine-2,6-dicarboxylic acid is expected to be soluble in water, particularly at higher temperatures.
  • Solvents: It may also exhibit solubility in other polar organic solvents due to its structure.

In conclusion, the solubility of 4-oxo-1H-pyridine-2,6-dicarboxylic acid is largely shaped by its functional groups which promote interactions with polar solvents, highlighting the intricate balance between molecular structure and solubility characteristics.

Interesting facts

Interesting Facts about 4-oxo-1H-pyridine-2,6-dicarboxylic acid

4-oxo-1H-pyridine-2,6-dicarboxylic acid, also known as quinaldic acid, is a fascinating compound that belongs to the class of carboxylic acids. Its unique structure and chemical properties provide numerous interesting insights for both scientists and students:

  • Biological Relevance: This compound plays a significant role in various biological systems, particularly in the metabolism of certain organisms. It has been linked to several biochemical pathways, making it relevant in biochemical research.
  • Precursor to Other Compounds: In synthetic organic chemistry, quinaldic acid serves as a precursor for the development of various pharmaceuticals and agrochemicals, highlighting its importance in the field of medicinal chemistry.
  • Research Applications: Studies have indicated that this compound exhibits potential anti-inflammatory properties, making it a subject of interest for researchers focused on drug discovery and development.
  • Unique Reactions: The reactivity of 4-oxo-1H-pyridine-2,6-dicarboxylic acid allows for a variety of chemical modifications, enabling chemists to create diverse derivatives that can be tailored for specific applications.
  • Historical Significance: The synthesis and study of quinaldic acid date back to the exploration of pyridine derivatives, showcasing the evolution of organic chemistry since the 19th century. As noted by chemists, "the exploration of pyridine derivatives has been a vital part of understanding heterocyclic compounds."

4-oxo-1H-pyridine-2,6-dicarboxylic acid is a prime example of how organic compounds can connect to biological mechanisms, serving both practical and theoretical purposes in modern scientific research.

Synonyms
CHELIDAMIC ACID
4-Hydroxypyridine-2,6-dicarboxylic acid
138-60-3
499-51-4
4-oxo-1,4-dihydropyridine-2,6-dicarboxylic acid
2,6-Pyridinedicarboxylic acid, 1,4-dihydro-4-oxo-
4-oxo-1H-pyridine-2,6-dicarboxylic acid
Chelidamic acid hydrate
Helidaminic acid
1A59BH8SXE
NSC 3983
NSC-3983
EINECS 205-335-8
MFCD00066478
UNII-1A59BH8SXE
CHEMBL252909
DTXSID00160451
4-HYDROXY-2,6-PYRIDINEDICARBOXYLIC ACID
1,4-dihydro-4-oxo-2,6-pyridinedicarboxylic acid
1,4-Dihydro-4-oxopyridine-2,6-dicarboxylic acid
4-Oxo-1,4-dihydro-2,6-pyridinedicarboxylic acid
2,6-Pyridinedicarboxylic acid, 4-hydroxy-
4-Chloro-alpha,alpha-diphenyl-benzenemethanol; (p-Chlorophenyl)diphenyl-methanol; 4-Chloro-alpha,alpha-diphenylbenzenemethanol; 4-Chlorophenyl)diphenylcarbinol; NSC 20739
Lopac-C-8011
Chelidamic acid, AldrichCPR
Lopac0_000298
MLS000042771
SCHEMBL742928
2, 1,4-dihydro-4-oxo-
DTXCID5082942
NSC3983
HMS2439A21
HMS3260L18
Tox21_500298
BBL028110
BDBM50229870
STK793046
STL259705
pyridine, 2,6-dicarboxy-4-hydroxy-
AKOS000279986
AKOS003233475
4-hydroxypyridine-2,6-dicarboxylicacid
CCG-204393
CS-W017065
DS-1684
FC34364
HY-W016349
LP00298
SDCCGSBI-0050286.P002
NCGC00015270-01
NCGC00015270-02
NCGC00015270-03
NCGC00015270-04
NCGC00015270-05
NCGC00093748-01
NCGC00093748-02
NCGC00260983-01
BP-12395
SMR000036248
SY246016
DB-012857
DB-082252
C0821
CS-0166907
EU-0100298
NS00041610
EN300-95632
C 8011
AC-907/25014159
AG-205/04716036
AG-690/09410046
SR-01000075782
4-Oxo-1,4-dihydro-2,6-pyridinedicarboxylic acid #
Q2667856
SR-01000075782-1
Z2900188067
2,6-Pyridinedicarboxylic acid, 1,4-dihydro-4-oxo-(8CI)
2,6-Pyridinedicarboxylic acid, 1,4-dihydro-4-oxo-(8CI)(9CI)
205-335-8
4-Oxo-1,4-dihydro-2,6-pyridinedicarboxylic acid hydrate;4-Hydroxy-pyridine-2,6-dicarboxylic acid hydrate