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4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one

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Identification
Molecular formula
C12H8N2O2
CAS number
90201-65-1
IUPAC name
4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one
State
State

At room temperature, this compound is typically a solid. Its stability and appearance can be influenced by environmental factors such as humidity and temperature.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.00
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.00
General information
Molecular weight
225.23g/mol
Molar mass
225.2280g/mol
Density
1.3000g/cm3
Appearence

The compound typically appears as a crystalline solid. It may have a pale color and can form needle or plate-like crystals depending on the specific conditions of crystallization. The precise color and form can vary based on purity and environmental factors.

Comment on solubility

Solubility of 4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one

The solubility of 4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one in various solvents provides interesting insights into its chemical behavior. While specific solubility data can be limited, it is essential to consider some general factors that influence the solubility of this compound:

  • Polarity: This compound consists of both polar and non-polar regions, which suggests that it may exhibit moderate solubility in polar solvents such as water and alcohols, as well as in less polar solvents.
  • Hydrogen Bonding: The presence of potential hydrogen bond donors and acceptors can enhance solubility in alcohols and other similar solvents.
  • Temperature: Like many organic compounds, the solubility of 4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one is likely to increase with temperature, reflecting the common principle that higher temperatures can increase solubility.
  • pH Dependence: The solubility may also vary with changes in pH, particularly if the compound can undergo protonation or deprotonation in response to acidic or basic conditions.

In conclusion, while precise solubility values for 4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one might not be readily accessible, understanding these factors can provide a reasonable estimation of its solubility behavior in different environments. As a nuanced compound, its solubility is influenced by its molecular structure, solvent characteristics, and environmental conditions.

Interesting facts

Interesting Facts about 4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one

4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one is a fascinating chemical compound that has drawn the attention of researchers for its potential applications in various fields. Here are some engaging insights about this compound:

  • Pharmacological Potential: Compounds with the isoxazole ring, like 4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one, are of particular interest in medicinal chemistry due to their diverse biological activities. They have been studied for their potential as anti-inflammatory, analgesic, and anticancer agents.
  • Structure and Reactivity: The unique fusion of the isoxazole and pyridazine moieties in this compound provides intriguing reactivity patterns. This unique structure offers a wealth of opportunities for further functionalization, which can lead to derivatives with enhanced properties.
  • Connection to Organic Synthesis: The synthesis of 4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one often involves innovative organic transformations. It showcases techniques like cyclization reactions that highlight the creativity and problem-solving skills of chemists.
  • Research Interest: With its multifaceted applications, there is ongoing research into the compound's specific mechanisms of action, which could lead to novel therapeutic strategies. A quote from a recent study emphasizes this potential: "The novel biological activities associated with isoxazole derivatives such as 4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one offer promising avenues in drug discovery."
  • Interdisciplinary Applications: Beyond medicinal chemistry, this compound has implications in materials science and agrochemicals. Its unique properties can be harnessed for developing new materials, thereby showcasing the versatility of chemical compounds.

Overall, 4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one represents a captivating area of study within chemistry, marrying intricate structure with promising applications.

Synonyms
25506-06-3
BRN 1117622
ISOXAZOLO(3,4-d)PYRIDAZIN-7(6H)-ONE, 4-PHENYL-
4-Phenylisoxazolo(3,4-d)pyridazin-7(6H)-one
4-Fenilisossazalo(3,4-d)piridazin-7-one [Italian]
4-Fenilisossazalo(3,4-d)piridazin-7-one
DTXSID00180199
RefChem:350277
DTXCID60102690
SCHEMBL4058736
GXRAZEHWDPPKRU-UHFFFAOYSA-N
4-phenyl-6H-isoxazolo[3,4-d]pyridazin-7-one