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4-Phenylbutan-2-amine

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Identification
Molecular formula
C10H15N
CAS number
7160-19-8
IUPAC name
4-phenylbutan-2-amine
State
State

At room temperature, 4-Phenylbutan-2-amine is generally in a solid state. It is stable under standard conditions and primarily encountered as crystalline solids.

Melting point (Celsius)
50.50
Melting point (Kelvin)
323.65
Boiling point (Celsius)
229.00
Boiling point (Kelvin)
502.15
General information
Molecular weight
149.23g/mol
Molar mass
149.2330g/mol
Density
1.0650g/cm3
Appearence

4-Phenylbutan-2-amine is typically found as a crystalline solid. Its appearance can vary slightly depending on its purity and form, but it predominantly exists as white or off-white crystals.

Comment on solubility

Solubility of 4-phenylbutan-2-amine

4-phenylbutan-2-amine, also known by its IUPAC name, exhibits specific solubility characteristics due to its molecular structure. Here are some key points regarding its solubility:

  • Solvent Dependence: The solubility of 4-phenylbutan-2-amine can vary significantly depending on the solvent used. It tends to dissolve readily in polar organic solvents such as ethanol and methanol.
  • Water Solubility: In terms of solubility in water, 4-phenylbutan-2-amine is relatively low. This is primarily due to its hydrophobic phenyl group, which hinders its interaction with water molecules.
  • Temperature Influence: As with many compounds, increasing the temperature may enhance its solubility in certain solvents. Therefore, one might observe improved solubility of this compound in heated conditions.
  • pH Factor: The solubility can also be influenced by the pH of the solution, as changes in acidity or basicity can affect the ionization state of the amine group, potentially enhancing its solubility in aqueous solutions when protonated.

In conclusion, while 4-phenylbutan-2-amine displays notable solubility in certain solvents, its overall water solubility remains limited, reflecting the balancing act between its hydrophobic and hydrophilic interactions. Understanding these solubility nuances is crucial for applications in chemical synthesis and formulation.

Interesting facts

4-Phenylbutan-2-amine: An Overview

4-Phenylbutan-2-amine, commonly known as a member of the phenethylamine family, is a fascinating compound due to its unique structural and functional properties. This compound has garnered attention in various fields, particularly in medicinal chemistry and neuroscience. Here are some notable facts:

Key Characteristics

  • Structural Diversity: The presence of a phenyl group attached to a butan-2-amine backbone presents opportunities for diverse chemical reactions and the creation of derivatives.
  • Biological Activity: Compounds in this class often exhibit interesting biological effects, including implications for neurotransmitter regulation, which paves the way for research in understanding mood disorders.
  • Potential Applications: Scientists are investigating its potential utility in the development of new pharmaceuticals aimed at treating conditions such as attention deficit hyperactivity disorder (ADHD) and other cognitive dysfunctions.

Interesting Uses and Research

The versatility of 4-phenylbutan-2-amine is reflected in its potential applications in:

  • Drug development: Exploring its efficacy and mechanisms of action can lead to breakthroughs in treating neurological disorders.
  • Research studies: As a subject of interest, it aids in understanding amino acid metabolism and psychological effects associated with various lifestyle changes.
  • Pharmaceutical formulations: Its unique properties make it a candidate for designing targeted delivery systems in medicine.

Conclusion

In summary, 4-phenylbutan-2-amine stands as an intriguing compound in medicinal chemistry and neuroscience. With its potential to aid in drug discovery and therapeutic applications, it continues to be a subject of ongoing research. As scientists delve deeper into its molecular characteristics, there is much to anticipate in the future applications of this compound.

Synonyms
1-Methyl-3-phenylpropylamine
4-phenylbutan-2-amine
22374-89-6
3-Amino-1-phenylbutane
1-Phenyl-3-aminobutane
4-Phenyl-2-aminobutane
1-Phenyl-3-amino-butan
Benzenepropanamine, alpha-methyl-
alpha-Methylbenzenepropanamine
NSC-115524
326655W66Z
DTXSID60871334
RefChem:100365
DTXCID10819004
244-942-2
2-Amino-4-phenylbutane
22148-77-2
4-Phenyl-2-butylamine
Propylamine, 1-methyl-3-phenyl-
Benzenepropanamine, .alpha.-methyl-
NSC 115524
1-Methyl-3-phenyl-propylamine
.alpha.-Methylbenzenepropanamine
MFCD00008090
3-Phenyl-1-methylpropylamine
4-phenylbut-2-ylamine
(R)-alpha-Methylbenzenepropanamine
1-Phenyl-3-amino-butan [German]
EINECS 244-942-2
alpha-Methyl-gamma-phenyl-N-propylamine
BRN 2413110
alpha-Methyl-gamma-phenyl-n-propylamin [German]
UNII-326655W66Z
NSC115524
Labetalol Impurity 9
alpha-Methyl-gamma-phenyl-n-propylamin
1-phenyl-3-butylamine
4-Phenyl-2-butanamine
LABETALOL_met006
PROPYLAMINE, alpha-METHYL-gamma-PHENYL-
benzene, (3-amino)butyl-
SCHEMBL1280
1-methy-3-phenylpropylamine
Benzenepropanamine, -methyl-
(3-AMINOBUTYL)BENZENE
1-methyl 3-phenyl-propylamine
Labetalol Impurity 6Amphetamine
SCHEMBL1569822
SCHEMBL1569826
SCHEMBL1673547
SCHEMBL4083215
SCHEMBL4351016
SCHEMBL7520872
WECUIGDEWBNQJJ-UHFFFAOYSA-
1-Methyl-3-phenylpropylamine, 98%
SBB059846
STL193993
AKOS000119752
AKOS016051338
AC-8354
PS-5334
SB47247
FM157635
PD214347
[(1S)-1-methyl-3-phenyl-propyl]ammonium
DB-367949
.alpha.-Methyl-.gamma.-phenyl-N-propylamine
A0999
CS-0022291
NS00050249
Propylamine, .alpha.-methyl-.gamma.-phenyl-
ST50824172
EN300-20027
A816167
F231006
Q27256149
F2190-0401
Z104476462
InChI=1/C10H15N/c1-9(11)7-8-10-5-3-2-4-6-10/h2-6,9H,7-8,11H2,1H3