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Astemizole

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Identification
Molecular formula
C28H31ClN2O2
CAS number
68844-77-9
IUPAC name
(4-phenylphenyl)methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium;chloride
State
State

At room temperature, Astemizole is in a solid state.

Melting point (Celsius)
225.00
Melting point (Kelvin)
498.00
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.00
General information
Molecular weight
458.04g/mol
Molar mass
458.0380g/mol
Density
1.1400g/cm3
Appearence

Astemizole typically appears as a white to off-white crystalline powder. It is known for its relatively fine granularity and solid form at room temperature.

Comment on solubility

Solubility of (4-phenylphenyl)methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium;chloride

When discussing the solubility of the compound (4-phenylphenyl)methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium;chloride, it's essential to consider various factors that influence its behavior in solvents. This compound features a complex structure that often impacts its solubility profile significantly.

Factors Influencing Solubility:

  • Molecular Composition: The presence of both phenyl groups and a quaternary ammonium cation suggests potential interactions that might increase solubility in polar solvents.
  • Structural Complexity: The sterically hindered nature of the norbornane framework can create hydrophobic character, potentially lowering solubility in water but aiding solubility in organic solvents.
  • Chloride Ion: Being a chloride salt, it may enhance solubility in aqueous solutions compared to its free base form.

Overall, while solubility tends to vary, it is reasonable to hypothesize that this compound may display:

  • Increased solubility in: Non-polar or slightly polar organic solvents like chloroform or methanol.
  • Reduced solubility in: Water due to its hydrophobic characteristics associated with the bulky phenyl groups.

In conclusion, the solubility of (4-phenylphenyl)methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium;chloride is likely to reflect a delicate balance between its ionic and hydrophobic properties, determining its effectiveness in various chemical applications.

Interesting facts

Interesting Facts about (4-phenylphenyl)methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium Chloride

This compound, a fascinating quaternary ammonium salt, is known for its unique structure and diverse applications in the field of chemistry and materials science. Here are some captivating aspects to consider:

  • Structural Diversity: The compound features a complex architecture incorporating both aromatic and alicyclic components, which can significantly influence its chemical properties and reactivity.
  • Role as a Surfactant: It functions effectively as a surfactant, helping to reduce surface tension in various formulations. This property makes it valuable in industries ranging from pharmaceuticals to cosmetics.
  • Ionic Characteristics: Being a quaternary ammonium salt, it possesses a positive charge that enhances its solubility in polar solvents, allowing it to interact with a wide range of molecules.
  • Applications in Material Science: Its unique chemical structure allows for usage in creating advanced materials, such as specialized polymers and ion-exchange resins.
  • Environmental Impact: Understanding the behavior and degradation pathways of ammonium salts is crucial in environmental chemistry, as they can affect local ecosystems and water systems.

As we analyze the potential applications and impacts of this compound, it's important to emphasize the role of innovative compounds like this one in advancing scientific knowledge and technological development. The integration of compound design with application-oriented research continues to inspire breakthroughs across various disciplines.

Synonyms
(+-)-endo-N-(p-Phenylbenzyl)-2-bornanamine hydrochloride
24629-68-3
4-BIPHENYLMETHYLAMINE, N-2-BORNYL-, HYDROCHLORIDE, endo-(+-)-
RefChem:290394