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4-Phenylpyridine

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Identification
Molecular formula
C11H9N
CAS number
531-88-4
IUPAC name
4-phenylpyridine
State
State

At room temperature, 4-Phenylpyridine is typically in a solid state.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
262.50
Boiling point (Kelvin)
535.65
General information
Molecular weight
155.20g/mol
Molar mass
155.2020g/mol
Density
1.0520g/cm3
Appearence

4-Phenylpyridine is a crystalline solid that typically appears as white to beige crystals. It may also be found in powder form, varying slightly in color from off-white to light yellow, depending on purity and presence of impurities.

Comment on solubility

Solubility of 4-phenylpyridine

4-Phenylpyridine (C11H9N) is a fascinating compound with noteworthy solubility characteristics. It is primarily soluble in organic solvents, which opens up various applications in chemical reactions and processes. The solubility of 4-phenylpyridine can be summarized as follows:

  • Solvent compatibility: It shows good solubility in non-polar and moderately polar solvents such as toluene, chloroform, and ethanol.
  • Temperature dependence: Like many organic compounds, its solubility tends to increase with temperature, enhancing its usability in various contexts.
  • Limited water solubility: 4-Phenylpyridine has low solubility in water, which is typical for many hydrophobic organic molecules.

Due to its low aqueous solubility, 4-phenylpyridine is particularly relevant in the fields of organic synthesis and pharmaceuticals, where its hydrophobic properties can be advantageous in specific applications. Understanding its solubility traits is crucial for effectively utilizing this compound in research and industry.

Interesting facts

Interesting Facts about 4-Phenylpyridine

4-Phenylpyridine is a fascinating heterocyclic compound that belongs to the class of pyridines. As a derivative of pyridine, it showcases unique properties and functional characteristics that make it of significant interest in the field of chemistry. Here are some key points to consider:

  • Structure: Its molecular structure features a pyridine ring with a phenyl group attached to the fourth carbon atom. This structural arrangement contributes to its chemical reactivity and interactions.
  • Applications: 4-Phenylpyridine is commonly used in various applications, including:
    • As a building block in organic synthesis
    • As a potential ligand in coordination chemistry
    • In the development of pharmaceuticals and agrochemicals
  • Biological Activity: This compound has shown potential for exhibiting biological activity. Research suggests it may have antimicrobial and antifungal properties, making it a candidate for further medicinal investigation.
  • Importance in Research: Scientists have been investigating 4-phenylpyridine for its role in catalysis and as a part of various chemical reactions. Its ability to engage in multiple types of interactions makes it valuable for exploring new chemical pathways.
  • Chemical Reactivity: The presence of the nitrogen atom in the pyridine ring makes 4-phenylpyridine a nucleophilic compound, allowing it to participate in a range of chemical reactions, including electrophilic substitutions.

As a cornerstone in many synthetic methodologies, 4-phenylpyridine stands out as a compound ripe for exploration. The intersection of its chemical properties and potential applications underscores the importance of such heterocycles in advancing both theoretical and practical aspects of chemistry.

Synonyms
4-PHENYLPYRIDINE
939-23-1
Pyridine, 4-phenyl-
p-Phenylpyridine
EINECS 213-357-4
NSC 70375
NSC 77935
BRN 0110490
452KD9YCG7
NSC-70375
NSC-77935
DTXSID5022140
5-20-07-00549 (Beilstein Handbook Reference)
pPhenylpyridine
Pyridine, 4phenyl
DTXCID602140
213-357-4
inchi=1/c11h9n/c1-2-4-10(5-3-1)11-6-8-12-9-7-11/h1-9
4-Phenyl-pyridine
MFCD00006420
Pyridine, phenyl-
4-Aza-1,1'-biphenyl
CHEMBL109074
4-Azabiphenyl
52642-16-7
UNII-452KD9YCG7
phenyl-pyridine
NSC 70375; NSC 77935; p-Phenylpyridine; gamma-Phenylpyridine
4-Phenylpyridin
?-Phenylpyridine
4-Pyridylbenzene
5SH
4-Phenylpyridine, 97%
MLS002206281
SCHEMBL124353
SCHEMBL19003057
CHEBI:173662
HMS2268O18
NSC70375
NSC77935
BDBM50121955
AKOS005255288
AC-5099
CS-W018018
NCGC00247406-01
DS-14724
SMR000112292
SY021647
DB-031355
NS00039765
P0162
EN300-49165
Q27258800