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4-Pyridylmethanol

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Identification
Molecular formula
C6H7NO
CAS number
586-95-8
IUPAC name
4-pyridylmethanol
State
State

At room temperature, 4-pyridylmethanol is found in a solid state. It may appear as either a fine powder or crystalline in nature.

Melting point (Celsius)
65.00
Melting point (Kelvin)
338.15
Boiling point (Celsius)
174.00
Boiling point (Kelvin)
447.15
General information
Molecular weight
109.13g/mol
Molar mass
109.1260g/mol
Density
1.1000g/cm3
Appearence

4-Pyridylmethanol appears as a white or pale yellow solid. It is typically crystalline in form, and due to its aromatic pyridine ring, it might have a faint pyridine-like odor.

Comment on solubility

Solubility of 4-pyridylmethanol

4-pyridylmethanol, with the chemical formula C6H7N, exhibits interesting solubility characteristics due to its functional groups and molecular structure.

Solubility Properties

  • Solvent Compatibility: This compound is generally soluble in polar solvents such as water, methanol, and ethanol, making it suitable for various applications in organic synthesis.
  • Hydrogen Bonding: The presence of the hydroxyl group (-OH) in 4-pyridylmethanol facilitates hydrogen bonding with water molecules, which enhances its solubility in aqueous solutions.
  • Limited Solubility in Non-Polar Solvents: Conversely, 4-pyridylmethanol exhibits poor solubility in non-polar solvents like hexane and benzene due to its polar nature.

In summary, the solubility of 4-pyridylmethanol can be attributed to its ability to form hydrogen bonds and its compatibility with polar solvents, while it tends to be less soluble in non-polar environments. As with many organic compounds, the solubility aspects can significantly influence its reactivity and usability in various chemical processes.

Interesting facts

Interesting Facts About 4-Pyridylmethanol

4-Pyridylmethanol is a fascinating compound that belongs to the family of pyridine derivatives. Its unique structure and properties contribute to its wide range of applications in various fields of chemistry and pharmacology. Here are some intriguing facts about this compound:

  • Structural Significance: As a pyridine derivative, 4-pyridylmethanol features a pyridine ring attached to a methanol group. This structure allows for versatile interactions in chemical reactions, making it a valuable intermediate in organic synthesis.
  • Role in Medicinal Chemistry: Researchers have explored the potential pharmacological effects of 4-pyridylmethanol, particularly its capacity to act as a building block for drug development. Its molecular framework can be modified to enhance bioactivity, aiding in the design of novel therapeutics.
  • Synthesis Methods: The compound can be synthesized through various pathways, including the reduction of 4-pyridinecarboxaldehyde. The knowledge of its synthesis is crucial for chemists interested in producing this compound for research and industrial purposes.
  • Reactivity: 4-Pyridylmethanol exhibits reactivity typical of alcohols, such as forming esters and participating in oxidation reactions. These characteristics enable chemists to utilize it to create more complex molecules.
  • Mechanistic Insights: Understanding the reaction mechanisms involving 4-pyridylmethanol can provide insights into various chemical processes, informing future research in synthetic and medicinal chemistry.

A renowned chemist once remarked, "The beauty of organic chemistry lies in the ability to transform simple compounds into complex forms with immense biological significance." 4-Pyridylmethanol exemplifies this notion, serving as a prime example of how seemingly simple molecular structures can lead to innovative advancements in science.

In summary, 4-pyridylmethanol is not only a building block in organic synthesis but also a compound with potential implications in drug design and development. With ongoing research, its significance in the field continues to unfold.

Synonyms
4-PYRIDINEMETHANOL
586-95-8
4-Pyridylcarbinol
4-(Hydroxymethyl)pyridine
4-Pyridylmethanol
4-Picolyl alcohol
4-Pyridinecarbinol
gamma-Picolyl alcohol
NSC 26024
NSC 49167
EINECS 209-590-6
DTXSID90870638
DTXCID20818341
209-590-6
PYRIDIN-4-YLMETHANOL
Pyridine-4-methanol
4-Hydroxymethylpyridine
4-Pyridinylmethanol
(Pyridin-4-yl)methanol
.gamma.-Picolyl alcohol
MFCD00006442
Pyridin-4-Yl-Methanol
4-pyridyl methanol
4-pyridyl-carbinol
4-pyridine methanol
4-pyridine-methanol
pyridine-4ylmethanol
(4-pyridyl)methanol
pyridine-4-ylmethanol
Pyridine, 4-carbinol
?-Hydroxy-4-picoline
Pyridine-4-methanol (4-Pyridylcarbinol)
Pyridine-4-yl-methanol
4-hydroxymethyl pyridine
4-hydroxymethyl-pyridine
4-Pyridinemethanol, 99%
4-(hydroxymethyl)-pyridine
PYRIDINE 4-METHANOL
pyridine, 4-hydroxymethyl-
4-(Hydroxymethylene)pyridine
SCHEMBL102606
CHEMBL1235528
SCHEMBL11019406
SCHEMBL11484804
ALBB-021945
NSC26024
NSC49167
NSC-26024
NSC-49167
STL386832
AKOS000248904
CS-W007605
SDCCGMLS-0065929.P001
AS-12010
BP-10053
PY7
SY003306
DB-016080
NS00042613
P0751
4-(Hydroxymethyl)pyridine;4-Pyridyl carbinol
EN300-64663
Q27464630
F0001-1532
Z335244866
InChI=1/C6H7NO/c8-5-6-1-3-7-4-2-6/h1-4,8H,5H