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4-pyridylmethyl N-(4-fluorophenyl)carbamate

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Identification
Molecular formula
C13H11FN2O2
CAS number
200296-83-7
IUPAC name
4-pyridylmethyl N-(4-fluorophenyl)carbamate
State
State

This compound is typically a solid at room temperature.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
374.00
Boiling point (Kelvin)
647.15
General information
Molecular weight
258.26g/mol
Molar mass
258.2590g/mol
Density
1.3200g/cm3
Appearence

This compound typically appears as a white to off-white crystalline solid.

Comment on solubility

Solubility of 4-pyridylmethyl N-(4-fluorophenyl)carbamate

The solubility of 4-pyridylmethyl N-(4-fluorophenyl)carbamate can be influenced by several factors related to its chemical structure and nature. Here are some key points to consider:

  • Polarity: This compound contains polar functional groups due to the presence of the carbamate moiety, which can increase its solubility in polar solvents such as water.
  • Hydrogen bonding: The potential for hydrogen bonding in this molecule can also enhance its solubility characteristics. The carbamate group can interact favorably with solvent molecules.
  • Solvent interaction: Solubility may vary significantly between solvents. For example, it may dissolve well in dimethyl sulfoxide (DMSO) or methanol, while showing reduced solubility in non-polar solvents.
  • Temperature dependency: As with many organic compounds, solubility can also be temperature-dependent, typically increasing as the temperature rises.

It is essential to note that while predicting solubility, empirical data is invaluable. As one quote states, "Experimentation speaks volumes where theory remains silent." Thus, for practical applications or formulations, laboratory solubility tests are recommended to confirm behavior in specific environments.

Interesting facts

Interesting Facts about 4-Pyridylmethyl N-(4-fluorophenyl)carbamate

4-Pyridylmethyl N-(4-fluorophenyl)carbamate is an intriguing compound that finds its relevance in various fields, particularly in medicinal chemistry and agrochemicals. Here are some fascinating aspects worth noting:

  • Pharmacological Potential: This compound is part of a larger class of carbamates, which are known for their biological activities. Many carbamate derivatives exhibit antimicrobial, anticancer, and anti-inflammatory properties, making them valuable in drug development.
  • Mechanism of Action: The carbamate functional group can interact with biological targets such as enzymes and receptors. For example, certain carbamates act by inhibiting the enzyme acetylcholinesterase, which plays a critical role in neurotransmission.
  • Fluorination Effects: The presence of the fluorine atom in the compound significantly alters its chemical behavior. Fluorinated compounds often demonstrate increased lipophilicity and enhanced bioavailability, making them suitable for pharmaceutical applications.
  • Versatile Applications: Beyond pharmaceuticals, this compound could potentially serve in agricultural chemistry, where it may function as a pesticide or herbicide. Its structural framework allows for modifications, enabling the design of molecules tailored for specific targets.
  • Historical Context: Carbamates have been utilized since the mid-20th century, with various derivatives being explored in both academia and industry. The exploration of 4-pyridylmethyl N-(4-fluorophenyl)carbamate continues the tradition of developing compounds with significant therapeutic promise.

Research into this compound not only deepens our understanding of carbamate chemistry but also paves the way for innovative therapeutic solutions. As scientists continue to explore and manipulate these structures, the possibilities for future applications seem boundless.

Synonyms
4867-61-2
p-Fluorocarbanilic acid 4-pyridylmethyl ester
4-Pyridylmethyl p-fluorocarbanilate
CARBANILIC ACID, p-FLUORO-, 4-PYRIDYLMETHYL ESTER
BRN 1537227
DTXSID30197578
DTXCID90120069
5-21-02-00193 (beilstein handbook reference)
4-Fluorophenylcarbamic acid 4-pyridylmethyl ester