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4-pyridylmethyl N-(p-tolyl)carbamate

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Identification
Molecular formula
C14H14N2O2
CAS number
115269-76-0
IUPAC name
4-pyridylmethyl N-(p-tolyl)carbamate
State
State

At room temperature, 4-pyridylmethyl N-(p-tolyl)carbamate exists in a solid state. Its crystalline form and stability contribute to it being solid under these conditions.

Melting point (Celsius)
123.00
Melting point (Kelvin)
396.15
Boiling point (Celsius)
351.20
Boiling point (Kelvin)
624.35
General information
Molecular weight
240.28g/mol
Molar mass
240.2770g/mol
Density
1.1980g/cm3
Appearence

4-Pyridylmethyl N-(p-tolyl)carbamate appears as a white crystalline solid. This type of compound can form distinct crystals that may have a characteristic sheen.

Comment on solubility

Solubility of 4-pyridylmethyl N-(p-tolyl)carbamate

The solubility of 4-pyridylmethyl N-(p-tolyl)carbamate is influenced by several factors, including its molecular structure and the presence of polar and nonpolar functional groups. Understanding the solubility characteristics of this compound can be quite intriguing:

  • Polarity: The molecule contains both hydrophilic (pyridyl group) and hydrophobic (p-tolyl group) portions, which contributes to its moderate solubility in most organic solvents.
  • Solvent Interaction: This compound tends to dissolve better in polar aprotic solvents such as DMSO or DMF due to the ability to interact with the lone pair electrons present in the nitrogen atom of the pyridyl group.
  • Temperature Effect: Solubility may increase with temperature, which is typical for many organic compounds, enhancing the kinetic energy of the molecules and allowing for better interaction with solvents.

To sum it up, the solubility of 4-pyridylmethyl N-(p-tolyl)carbamate is reasonable in organic solvents and is affected by structural elements impacting polarity and solvent interactions. For practical applications, it's essential to experiment under various conditions to determine the optimal solvent and temperature for dissolving this specific compound. Understanding these solubility dynamics can lead to successful formulations in both laboratory and industrial settings.

Interesting facts

Interesting Facts about 4-Pyridylmethyl N-(p-tolyl)carbamate

4-Pyridylmethyl N-(p-tolyl)carbamate is a fascinating compound that features both a pyridine ring and a carbamate functional group, which opens the door to various applications in the fields of chemistry and pharmacology. Here are some intriguing aspects of this compound:

  • Structure and Functionality: The presence of the pyridine ring imparts unique electronic properties to the molecule, often enhancing its ability to interact with biological systems.
  • Reactivity: As a carbamate derivative, it possesses a reactive carbonyl group, making it a versatile building block for the synthesis of more complex organic compounds.
  • Potential Biological Activity: Compounds like this have been explored for their potential as antimicrobial agents or in the treatment of various diseases, owing to their specific interactions with biological targets.
  • Synthetic Pathways: The synthesis of 4-pyridylmethyl N-(p-tolyl)carbamate may involve several strategies, including N-alkylation and carbamoylation reactions, showcasing the compound's organic synthesis relevance.
  • Research Interest: Ongoing research into carbamates has broadened understanding of their effects on enzyme systems, which has significant implications for drug design and discovery.

In conclusion, the intriguing structure and properties of 4-pyridylmethyl N-(p-tolyl)carbamate make it a significant subject of study in both theoretical and applied chemistry. Its potential applications in medicine and biochemistry continue to fuel curiosity and research in the compound's behavior and utility.

Synonyms
4867-60-1
p-Methylcarbanilic acid 4-pyridylmethyl ester
CARBANILIC ACID, p-METHYL-, 4-PYRIDYLMETHYL ESTER
BRN 1535482
DTXSID70197577
DTXCID30120068
5-21-02-00193 (beilstein handbook reference)
SCHEMBL8202632