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4-Sulfamoylbenzoic acid

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Identification
Molecular formula
C7H7NO4S
CAS number
6496-88-8
IUPAC name
4-sulfamoylbenzoic acid
State
State
4-Sulfamoylbenzoic acid is a solid at room temperature, existing primarily in a dry powder form.
Melting point (Celsius)
290.00
Melting point (Kelvin)
563.15
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.15
General information
Molecular weight
201.20g/mol
Molar mass
201.1960g/mol
Density
1.6720g/cm3
Appearence

4-Sulfamoylbenzoic acid typically appears as a white crystalline powder. It is known for its distinctive crystalline structure, contributing to its solid form at room temperature.

Comment on solubility

Solubility of 4-sulfamoylbenzoic acid

4-sulfamoylbenzoic acid is known to exhibit a range of solubility characteristics, primarily influenced by its chemical structure and the presence of functional groups. Understanding its solubility is crucial for various applications, especially in pharmaceuticals and material sciences.

Key Points of Solubility:

  • Water Solubility: This compound tends to be soluble in water due to the presence of the sulfonamide group, which can engage in hydrogen bonding with water molecules.
  • Organic Solvents: It may have varying solubility in organic solvents such as ethanol and DMSO, often dependent on the concentration and temperature.
  • pH Influence: The solubility can significantly change with pH; in acidic environments, 4-sulfamoylbenzoic acid is typically more soluble compared to neutral or alkaline conditions.
  • Temperature Effects: Like many organic compounds, solubility often increases with rising temperature, which is important to consider during dissolution processes.

As highlighted by its properties, “the solubility of chemical compounds can dictate their utility in various processes.” Hence, for precise applications, conducting solubility tests under expected conditions is always recommended to ensure optimal usage.

Interesting facts

Interesting Facts About 4-Sulfamoylbenzoic Acid

4-Sulfamoylbenzoic acid is a fascinating compound that has garnered attention in various scientific fields due to its unique structure and properties. Here are some interesting aspects of this compound:

  • Pharmaceutical Applications: This compound is known for its role in developing pharmaceuticals. Its sulfonamide group is pivotal for its antibacterial properties, making it a valuable scaffold in drug design.

  • Biochemical Significance: 4-Sulfamoylbenzoic acid is often studied for its interaction with enzymes and proteins. Its ability to mimic certain biological molecules allows it to explore mechanisms of action in biological pathways.

  • Versatile Chemical Reactivity: The functional groups in 4-sulfamoylbenzoic acid allow for diverse chemical reactions, including sulfonation and acetylation, which offer avenues for synthesizing complex compounds.

  • Environmental Impact: The stability and persistence of sulfonamides, including this compound, raise questions regarding their environmental effects and ecological interactions, thereby enticing researchers to examine the environmental fate of these chemicals.

  • Research Interest: Its capabilities in biological systems lead to ongoing research, particularly in the fields of medicinal chemistry and drug development. Scientists are keen to discover how modifications to the structure of 4-sulfamoylbenzoic acid can lead to improved efficacy and reduced side effects.

Overall, 4-sulfamoylbenzoic acid stands out not just as a compound with practical applications but also as a jumping-off point for exciting future research and exploration in both chemistry and biology.

Synonyms
4-Sulfamoylbenzoic acid
Carzenide
138-41-0
4-Carboxybenzenesulfonamide
4-(Aminosulfonyl)benzoic acid
Benzoic acid, 4-(aminosulfonyl)-
Carzenid
Dirnate
p-Sulfamoylbenzoic acid
p-Carboxybenzenesulfonamide
p-Sulfamylbenzoic acid
Carzenide [INN]
Benzoic acid p-sulfamide
p-Sulfonamidobenzoic acid
4-Aminosulfonylbenzoic acid
4-Sulfamylbenzoic acid
Carzenida
Carzenidum
4-Sulfamoylbenzoesaeure
Carzenidum [INN-Latin]
Carzenida [INN-Spanish]
BENZOIC ACID, p-SULFAMOYL-
NSC 22976
NSC-22976
4-sulfamolybenzoic acid
Carcenida
Benzoic acid 4-sulfamide
NSC22976
EINECS 205-327-4
Carzenide (INN)
BRN 1875393
30Z5HQB5A4
DTXSID1045089
CARZENIDE [MI]
MFCD00007938
CARZENIDE [MART.]
CHEMBL414
CARZENIDE [WHO-DD]
Para-Carboxybenzenesulfonamide
DTXCID9025089
UCAGLBKTLXCODC-UHFFFAOYSA-
NSC683540
NCGC00013287-06
NCGC00013287-07
Carzenidum (INN-Latin)
Carzenida (INN-Spanish)
CARZENIDE (MART.)
4-Sulfamoyl-benzoic acid
CAS-138-41-0
4-Sulfamidobenzoic acid
SR-01000000114
UNII-30Z5HQB5A4
4SO
pSulfamylbenzoic acid
4Sulfamoylbenzoesaeure
pSulfamoylbenzoic acid
4Sulfamoylbenzoic acid
4-sulamoylbenzoic acid
Benzoic acid psulfamide
pSulfonamidobenzoic acid
Benzoic acid 4sulfamide
p-sulphamoylbenzoic acid
Benzoic acid, psulfamoyl
pCarboxybenzenesulfonamide
4carboxybenzenesulfonamide
4aminosulfonylbenzoic acid
Maybridge1_002385
4-Carboxyphenylsulfonamide
4-sulphamoyl-benzoic acid
Benzoic Acid deriv. 31
p-Aminosulfonylbenzoic acid
4-carboxy-benzenesulfonamide
Cambridge id 5121815
benzoic acid, 4-sulfamoyl-
NCIStruc1_000566
NCIStruc2_000413
p-Aminosulfonyl-benzoic Acid
4(Aminosulfonyl)benzoic acid
Oprea1_448551
4-carboxybenzenesulfonamide 1
JMC52646 Compound 23
MLS000069605
DivK1c_001137
SCHEMBL312419
4-Carboxybenzenesulfonamide (4-Sulfamoylbenzoic acid)
4-Sulfamoylbenzoic acid, 97%
BDBM4703
JMC522226 Compound 22
JMC523116 Compound 22
Benzoic acid, 4(aminosulfonyl)
P-SULFAMOYL-BENZOIC ACID
HMS548E09
4-(Aminosulfonyl)benzoic acid #
CHEBI:177418
HMS2234G21
HMS3264O07
HMS3369M14
Pharmakon1600-01504505
HY-B0989
NCI22976
Tox21_110021
BBL011102
CCG-38010
NCGC00013287
NSC758886
s4556
STK802346
AKOS000144547
aromatic/heteroaromatic sulfonamide 23
Tox21_110021_1
CS-4482
NSC-683540
NSC-758886
SB78174
CDS1_000097
NCGC00013287-02
NCGC00013287-03
NCGC00013287-04
NCGC00013287-05
NCGC00021607-03
NCGC00021607-04
AS-14571
NCI60_001869
SMR000059013
SBI-0054135.P002
EU-0033692
NS00024481
EN300-16248
D09322
AB00384334_11
CS-009/03918038
SR-01000000114-2
SR-01000000114-3
SR-01000000114-4
BRD-K09295674-001-08-0
BRD-K09295674-001-09-8
Q27255987
Z53021532
F0347-1766
205-327-4
937-141-0