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4-tert-Butylpyridine

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Identification
Molecular formula
C9H13N
CAS number
3978-81-2
IUPAC name
4-tert-butylpyridine
State
State

At room temperature, 4-tert-butylpyridine is typically a liquid. It is used in various chemical applications where such pyridines are applicable.

Melting point (Celsius)
-58.00
Melting point (Kelvin)
215.15
Boiling point (Celsius)
197.00
Boiling point (Kelvin)
470.15
General information
Molecular weight
135.21g/mol
Molar mass
135.2070g/mol
Density
0.9167g/cm3
Appearence

4-tert-Butylpyridine appears as a colorless to pale yellow liquid. It is known for its characteristic odor, typically associated with pyridine derivatives.

Comment on solubility

Solubility of 4-tert-butylpyridine

4-tert-butylpyridine, with the chemical formula C11H15N, is a fascinating compound in terms of its solubility characteristics. Understanding its solubility is crucial for various applications:

  • Solvent Properties: 4-tert-butylpyridine is known to be soluble in polar and non-polar solvents, making it quite versatile. It dissolves well in common organic solvents such as:
    • Ethyl acetate
    • Toluene
    • Acetonitrile
  • Water Solubility: Interestingly, 4-tert-butylpyridine has limited solubility in water due to its hydrophobic tert-butyl group. Its behavior in water can be described as:
    • Low solubility – often related to the size and structure of the molecule.
    • Can participate in interactions at the air-water interface, influencing its overall solubility.
  • Temperature Effects: Solubility can change with temperature, generally increasing with higher temperatures. This property can be essential in designing experiments and reactions.

In summary, 4-tert-butylpyridine showcases intriguing solubility traits that are essential for its utilization in organic chemistry and material science. Its solubility in organic solvents highlight its applications, while its limited solubility in water underscores the importance of temperature and solvent choice in practical scenarios.

Interesting facts

Interesting Facts about 4-tert-butylpyridine

4-tert-butylpyridine is a fascinating compound that is widely recognized in the field of organic chemistry due to its unique structural and chemical properties. Here are some intriguing aspects about this compound:

  • Structure and Function: The presence of the tert-butyl group enhances the lipophilicity of the pyridine ring, making it an excellent candidate for various applications in organic synthesis.
  • Catalytic Role: 4-tert-butylpyridine is often used as a catalyst in reactions involving nucleophilic substitutions, particularly in the synthesis of pharmaceuticals and agrochemicals.
  • pH Sensitivity: The compound exhibits basicity due to the nitrogen atom in the pyridine ring, which can participate in protonation reactions, thereby influencing pH in chemical processes.
  • Applications: Its derivatives are commonly utilized as ligands in coordination chemistry, enhancing the solubility of metal complexes in organic solvents.
  • Biological Activity: Research shows that 4-tert-butylpyridine and its derivatives have exhibited interesting biological activities, including antimicrobial properties.

As a conclusion, *4-tert-butylpyridine* serves as a prime example of how small changes in chemical structure can lead to significant alterations in properties and applications. The compound continues to be a subject of research and interest among chemists, owing to its versatility and effectiveness in various chemical reactions.

Synonyms
4-tert-Butylpyridine
3978-81-2
Pyridine, 4-(1,1-dimethylethyl)-
Pyridine, 4-tert-butyl-
p-tert-Butyl pyridine
UNII-IL8V02163I
4-(t-Butyl)pyridine
IL8V02163I
NSC 5104
NSC-5104
EINECS 223-614-2
AI3-36657
DTXSID20192855
Pyridine, 4tertbutyl
Pyridine, 4tertbutyl (8CI)
Pyridine, 4(1,1dimethylethyl)
Pyridine, 4-tert-butyl-(8CI)
DTXCID60115346
223-614-2
inchi=1/c9h13n/c1-9(2,3)8-4-6-10-7-5-8/h4-7h,1-3h
yshmqtrichylgf-uhfffaoysa-n
4-(TERT-BUTYL)PYRIDINE
4-t-butylpyridine
4-tert-Butyl-pyridine
MFCD00006435
NSC5104
4-tertbutylpyridine
4-t-butyl pyridine
4-tert.butylpyridine
4-tert-butyl pyridine
4-tert- Butylpyridine
pyridine, 4-t-butyl-
Pyridine,1-dimethylethyl)-
SCHEMBL65312
4-tert-Butylpyridine, 96%
CHEBI:195158
BCP27511
AKOS000120207
CS-W002002
FB11129
AS-10326
SY010877
DB-049483
B0388
NS00030667
EN300-20692
Q10846092