Skip to main content

4-Thiocyanatobenzoic acid

ADVERTISEMENT
Identification
Molecular formula
C8H5NO2S
CAS number
4401-65-0
IUPAC name
4-thiocyanatobenzoic acid
State
State

At room temperature, 4-thiocyanatobenzoic acid is in a solid state.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
254.00
Boiling point (Kelvin)
527.15
General information
Molecular weight
181.20g/mol
Molar mass
181.2000g/mol
Density
1.4270g/cm3
Appearence

4-Thiocyanatobenzoic acid typically appears as a white to light-yellow crystalline powder. Its coloration may vary depending on purity and form.

Comment on solubility

Solubility of 4-Thiocyanatobenzoic Acid

The solubility of 4-thiocyanatobenzoic acid in various solvents is a crucial aspect to consider, especially in reactions and applications where this compound is involved. Here are some key points regarding its solubility:

  • Aqueous Solubility: 4-thiocyanatobenzoic acid tends to have limited solubility in water. This is primarily due to the presence of its hydrophobic benzene ring, which hinders interactions with water molecules.
  • Organic Solvents: It shows better solubility in organic solvents such as ethanol and acetone, where its polarity can be better accommodated.
  • Temperature Influence: Increasing the temperature of the solvent can enhance its solubility. According to the principle of solubility, higher temperatures often facilitate the dissolution of solids.
  • pH Dependence: The solubility of 4-thiocyanatobenzoic acid may vary with pH shifts, as it can undergo ionization in more alkaline conditions, potentially increasing its solubility in water.

In summary, the solubility characteristics of 4-thiocyanatobenzoic acid are influenced by the choice of solvent, temperature, and pH environment. Understanding these factors is essential for its effective use in chemical applications and synthesis processes.

Interesting facts

Interesting Facts about 4-Thiocyanatobenzoic Acid

4-Thiocyanatobenzoic acid is a fascinating compound that showcases the intriguing interplay between organic chemistry and biochemical applications. Here are some engaging aspects of this compound:

  • Composition and Structure: As a member of the benzoic acid family, 4-thiocyanatobenzoic acid exhibits a unique structure characterized by the presence of a thiocyanate group (-SCN) attached to a benzoic acid framework. This configuration affects its chemical behavior significantly.
  • Applications in Research: This compound has garnered interest in various fields, particularly:
    • Biochemistry: It serves as a reagent in biochemical studies, aiding in the analysis of enzyme activities.
    • Synthetic Chemistry: Used in the synthesis of other complex molecules, its reactivity makes it a valuable intermediate.
    • Materials Science: Researchers explore its potential in developing organic materials due to its unique properties.
  • Toxicity and Safety: While working with 4-thiocyanatobenzoic acid, it’s crucial to note that compounds containing thiocyanate groups may pose certain toxicological risks. Proper safety measures should be adhered to, including the use of personal protective equipment (PPE).
  • Environmental Impact: As with many sulfur-containing compounds, understanding the environmental fate of 4-thiocyanatobenzoic acid is essential for ensuring minimal ecological disturbance. Ongoing studies focus on its biocompatibility and degradation pathways.
  • Analytical Techniques: Scientists typically utilize various techniques such as NMR (Nuclear Magnetic Resonance) and FT-IR (Fourier Transform Infrared Spectroscopy) to study this compound extensively. These methods provide key insights into its structural, functional, and interaction properties.

In summary, 4-thiocyanatobenzoic acid is more than just a chemical; it plays significant roles across multiple research domains, demonstrating how intricate and impactful chemical compounds can be in scientific exploration.

Synonyms
p-Thiocyanobenzoic acid
16671-88-8
BENZOIC ACID, p-THIOCYANO-
Kyselina p-thiokyanatobenzoova
Kyselina p-thiokyanatobenzoova [Czech]
BRN 3248042
DTXSID10168165
4-10-00-00503 (Beilstein Handbook Reference)
DTXCID7090656
4-thiocyanatobenzoic acid
p-Thiocyanatobenzoic acid
Thiocyanobenzoic acid, p-
66RBE3PR3E
Benzoic acid, 4-thiocyanato-
SCHEMBL8713271
AKOS032951069