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Ipratropium bromide

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Identification
Molecular formula
C20H30BrF3NO
CAS number
22254-24-6
IUPAC name
[4-(trifluoromethyl)phenyl]methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium;bromide
State
State

At room temperature, ipratropium bromide is in a solid state, typically appearing as a white crystalline powder.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
490.00
Boiling point (Kelvin)
763.15
General information
Molecular weight
430.37g/mol
Molar mass
430.3930g/mol
Density
1.2141g/cm3
Appearence

Ipratropium bromide typically appears as a white crystalline powder. It is hydroscopic and is freely soluble in water and ethanol.

Comment on solubility

Solubility of [4-(trifluoromethyl)phenyl]methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium Bromide

The solubility characteristics of [4-(trifluoromethyl)phenyl]methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium bromide can be quite intriguing due to its unique molecular structure. Here are some key insights into its solubility:

  • Polarity: The presence of the trifluoromethyl group typically increases hydrophobicity, while the ammonium component tends to enhance solubility in polar solvents.
  • Solvent Interactions: This compound is likely to dissolve well in polar aprotic solvents such as acetone or acetonitrile due to its ammonium ion.
  • Hydrophilicity vs Hydrophobicity: The dual nature of the molecule (combining hydrophilic ammonium and hydrophobic fluorinated aromatic group) can lead to complex solubility behaviors, making it soluble in a mixture of solvents.
  • Ion Pairing: The bromide ion can influence the overall solubility. It is a good leaving group that may enhance the solubility by forming ionic interactions with other molecules.

As a general note, while the solubility of [4-(trifluoromethyl)phenyl]methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium bromide in aqueous solutions may be limited, its versatility in organic solvents makes it a compound worthy of detailed solubility studies. Factors such as temperature, solvent choice, and concentration gradients should be considered for precise applications in chemical contexts.

Interesting facts

Interesting Facts about [4-(Trifluoromethyl)phenyl]methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium Bromide

This remarkable compound, often classified under quaternary ammonium salts, showcases interesting properties and applications. Here are several key highlights to ponder:

  • Utilitarian Aspects: Compounds like this play crucial roles in various fields including organic synthesis, pharmaceuticals, and material science.
  • Fluorinated Features: The presence of the trifluoromethyl group (*-CF3*) imparts unique physical and chemical properties, enhancing lipophilicity and stability.
  • Norbornane Framework: This compound contains a norbornan structure, known for its strain and reactivity. Such frameworks are pivotal in building complex organic molecules.
  • Ion Exchange Applications: Often used in various ion exchange processes, quaternary ammonium salts exhibit remarkable performance in high-selectivity separations.
  • Biological Activity: Variations in ammonium salts have been explored for their antibacterial and antifungal properties, making them invaluable in medical applications.

As intriguing as it is complex, [4-(trifluoromethyl)phenyl]methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium bromide draws attention not only for its specialized chemical characteristics but also for its potential in advancing scientific understandings. To quote a famous chemist, "The beauty of chemistry lies in the endless possibilities it presents." This compound is a testament to such possibilities, merging diverse chemical functionalities into one innovative structure.

Synonyms
(+-)-endo-N-(p-(Trifluoromethyl)benzyl)-2-bornanamine hydrobromide
24629-63-8
2-BORNANAMINE, N-(p-(TRIFLUOROMETHYL)BENZYL)-, HYDROBROMIDE, endo-(+-)-
RefChem:256677