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4-Trimethylsilylbutyl carbamate

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Identification
Molecular formula
C9H21NO2Si
CAS number
84595-19-9
IUPAC name
4-trimethylsilylbutyl carbamate
State
State

4-Trimethylsilylbutyl carbamate is typically found in the liquid state at room temperature.

Melting point (Celsius)
-48.00
Melting point (Kelvin)
225.15
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.15
General information
Molecular weight
203.35g/mol
Molar mass
203.3480g/mol
Density
0.8917g/cm3
Appearence

4-Trimethylsilylbutyl carbamate is a colorless to pale yellow liquid. Its appearance may vary slightly depending on purity and conditions, but it generally remains clear and free from particulates.

Comment on solubility

Solubility of 4-trimethylsilylbutyl carbamate

4-trimethylsilylbutyl carbamate is an intriguing compound with notable solubility characteristics. When examining its solubility, several key factors come into play:

  • Polarity: The presence of the carbamate functional group (due to the -NH and -COO moieties) contributes to a degree of polarity, making it more soluble in polar solvents.
  • Solvent Type: It exhibits favorable solubility in a range of solvents, particularly:
    • Water
    • Alcohols (e.g., methanol, ethanol)
    • Some organic solvents (e.g., dimethyl sulfoxide, DMSO)
  • Temperature Influence: The solubility of 4-trimethylsilylbutyl carbamate increases with temperature, typical of many chemical compounds.

It's essential to note that while this compound demonstrates good solubility in certain solvents, it may have limited solubility in non-polar solvents due to its polar functional groups. This property is crucial for its applications in various chemical processes and formulations.

In summary, the solubility of 4-trimethylsilylbutyl carbamate showcases the complex interplay of molecular structure and solvent interactions, highlighting its potential versatility in different chemical environments.

Interesting facts

Interesting Facts about 4-Trimethylsilylbutyl Carbamate

4-Trimethylsilylbutyl carbamate is a fascinating compound known for its versatile applications in various fields of chemistry and industry. Here are some intriguing aspects:

  • Functional Group Diversity: The presence of the carbamate functional group in this compound allows for unique reactivity and properties that can be exploited in organic synthesis. Carbamates are often used as intermediates in the preparation of pharmaceuticals.
  • Silyl Groups: This compound contains trimethylsilyl (TMS) groups, which are pivotal in enhancing the solubility and stability of the compound. Silyl modifications can improve the overall reactivity of molecules, making them more amenable to various chemical transformations.
  • Applications in Synthesis: 4-Trimethylsilylbutyl carbamate is particularly useful in synthetic organic chemistry. It serves as a protective group for amines, allowing chemists to manipulate other functional groups without interfering with the protected amine.
  • Role in Analytical Chemistry: The compound finds its place in analytical methods such as Gas Chromatography-Mass Spectrometry (GC-MS), where it may act as a derivatizing agent to improve the volatility and detectability of analytes.
  • Combinatorial Chemistry: Its unique structure makes it beneficial for applications in combinatorial chemistry where libraries of compounds are synthesized rapidly for drug discovery. The ability to vary the silyl group allows for extensive exploration of molecular characteristics.

As noted by many chemists, “The possibilities with functionalized compounds are endless; they open avenues to creativity and discovery.” The ability to utilize the protective characteristics of carbamates while leveraging the advantages of silyl groups makes 4-trimethylsilylbutyl carbamate a valuable compound for both research and practical applications in chemistry.

Synonyms
BUTANOL, 4-(TRIMETHYLSILYL)-, CARBAMATE
4-(Trimethylsilyl)butanol carbamate
Carbamic acid, 4-(trimethylsilyl)butyl ester
BRN 2411455
3121-84-4
4-(Trimethylsilyl)butyl ester of carbamic acid
DTXSID90185138
DTXCID00107629