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4-Trimethylsilylphenol

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Identification
Molecular formula
C9H14OSi
CAS number
18737-91-0
IUPAC name
4-trimethylsilylphenol
State
State

At room temperature, 4-Trimethylsilylphenol is a liquid. Its relatively low melting point indicates that it remains in liquid form under normal laboratory conditions.

Melting point (Celsius)
-39.00
Melting point (Kelvin)
234.15
Boiling point (Celsius)
79.00
Boiling point (Kelvin)
352.15
General information
Molecular weight
166.29g/mol
Molar mass
166.2890g/mol
Density
0.9930g/cm3
Appearence

4-Trimethylsilylphenol is usually encountered as a colorless to pale yellow liquid. Its clarity and lack of color make it appear similar to other organic small molecules in its class.

Comment on solubility

Solubility of 4-Trimethylsilylphenol

The solubility of 4-trimethylsilylphenol (C9H14OSi) can be influenced by various factors such as its molecular structure and interactions with solvents. This compound is characterized by the presence of a trimethylsilyl group, which significantly affects its solubility properties.

Key Characteristics of Solubility

  • Polarity: The overall polarity of 4-trimethylsilylphenol is moderated by the trimethylsilyl group, making it less polar than simple phenols. This can affect its solubility in polar solvents.
  • Solvent Compatibility: It tends to be soluble in organic solvents such as ether, benzene, and chloroform, while exhibiting limited solubility in water due to hydrophobic character.
  • Temperature Effects: Solubility can change with temperature; generally, increasing temperature enhances solubility in organic solvents.

In summary, while 4-trimethylsilylphenol has moderate solubility in organic solvents, its limited solubility in water can be attributed to the non-polar nature of the trimethylsilyl group. This information is essential for applications where solvent choice plays a critical role in chemical reactions.

Interesting facts

Interesting Facts about 4-Trimethylsilylphenol

4-Trimethylsilylphenol is a fascinating chemical compound that has garnered interest in both academic and industrial realms. Here are some noteworthy points about this unique compound:

  • Structure: The addition of a trimethylsilyl group enhances the molecule's stability and solubility, making it a valuable derivative in various chemical reactions.
  • Applications in Chemistry: It is widely utilized as a protecting group in organic synthesis, particularly for phenolic compounds. This property allows chemists to manipulate structures without disrupting other sensitive functional groups.
  • Role in Spectroscopy: 4-Trimethylsilylphenol serves as an effective internal standard in NMR spectroscopy, enabling accurate measurement and analysis of complex mixtures.
  • Influence in Development: Researchers are exploring its potential in pharmaceuticals and organic materials due to its unique electronic properties and functional versatility.
  • Synthesis: The methods to synthesize 4-trimethylsilylphenol often involve straightforward strategies such as direct silylation of phenolic compounds, showcasing its accessibility for laboratory use.

As with many chemical compounds, understanding its properties and applications can lead to innovative solutions in various fields, from medicine to advanced material science. The exploration of compounds like 4-trimethylsilylphenol highlights the importance of harnessing organic chemistry for technological advancements.

Synonyms
4-(trimethylsilyl)phenol
4-TRIMETHYLSILYLPHENOL
p-Trimethylsilylphenol
Phenol, 4-(trimethylsilyl)-
3Y7UD24BHD
CHEBI:39394
NSC 83941
NSC-83941
UNII-3Y7UD24BHD
DTXSID0065359
PHENOL, P-(TRIMETHYLSILYL)-
(4-HYDROXYPHENYL)TRIMETHYLSILANE
DTXCID7034040
634-162-4
13132-25-7
NSC83941
NCIOpen2_001253
SCHEMBL78718
SCHEMBL1042641
CHEMBL2313451
AKOS024337479
BS-27323
DB-205304
CS-0107197
D76703
Q27119845