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Roxarsone

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Identification
Molecular formula
C6H8AsNO4
CAS number
121-19-7
IUPAC name
(4-ureidophenyl)arsonic acid
State
State

At room temperature, Roxarsone is in a solid state. It appears as a crystalline powder, typically white or light tan in color.

Melting point (Celsius)
164.50
Melting point (Kelvin)
437.70
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
263.05g/mol
Molar mass
263.0520g/mol
Density
1.9230g/cm3
Appearence

Roxarsone appears as a white to light tan crystalline powder. It is slightly soluble in water and has a neutral pH in its aqueous form.

Comment on solubility

Solubility of (4-ureidophenyl)arsonic acid

(4-ureidophenyl)arsonic acid is known for its unique structural characteristics, which significantly influence its solubility in various solvents. The solubility of this compound can be summarized as follows:

  • Polar solvents: (4-ureidophenyl)arsonic acid exhibits good solubility in polar solvents such as water and methanol due to the presence of hydrophilic functional groups.
  • Non-polar solvents: In stark contrast, the compound demonstrates limited solubility in non-polar solvents like benzene or hexane, primarily due to the lack of significant non-polar interactions.
  • Temperature dependence: The solubility may also vary with temperature; generally, higher temperatures lead to increased solubility in aqueous solutions.

Such solubility behavior can be crystallized with the saying, "Like dissolves like." This emphasizes the importance of chemical structure in determining solubility. Therefore, in practical applications, understanding the solubility of (4-ureidophenyl)arsonic acid is crucial for its effective use in formulations and chemical processes, allowing chemists to predict its behavior in different environments.

Interesting facts

Interesting Facts about (4-Ureidophenyl)arsonic Acid

(4-Ureidophenyl)arsonic acid is a fascinating chemical compound that sits at the intersection of organic chemistry and environmental science. This aromatic arsenic-based compound has garnered attention due to its unique structure and potential applications.

Key Features and Applications

  • Pharmaceutical Interest: Researchers have explored (4-ureidophenyl)arsonic acid for its potential use in medicinal chemistry, particularly in drug development. Its ability to interact with biological systems makes it a subject of various studies.
  • Environmental Concerns: As an organoarsenic compound, it prompts discussions about the environmental impact of arsenic-containing substances. Scientists are investigating how these compounds behave in ecosystems and their long-term effects.
  • Analytical Chemistry: This compound can be utilized as a reference material in analytical chemistry, aiding in the development of methods to detect arsenic in environmental samples.

Chemical Behavior

The chemical behavior of (4-ureidophenyl)arsonic acid is of great interest due to its reactivity. Some notable characteristics include:

  • Functional Versatility: The presence of both an amide and an arsonic acid group allows for diverse chemical reactions, making it a useful building block in organic synthesis.
  • Biochemical Interactions: Studies suggest that the compound's structure might facilitate interesting interactions with enzymes and proteins, which is crucial in drug development research.

Conclusion

In concluding, (4-ureidophenyl)arsonic acid exemplifies the unique characteristics and challenges posed by organoarsenic compounds. Its dual role in pharmaceutical and environmental studies offers a glimpse into the intricate balance between chemistry and the world around us. As we continue to explore these compounds, we must remain cognizant of their implications for health and the environment.

Synonyms
Carbarsone
121-59-5
Carbarson
Amebarsone
Aminarson
Pentarsone
Ameban
Amebarsene
Arsambide
Fenarsone
Leucarsone
p-Arsonophenylurea
Amibiarson
Aminarsone
Aminoarson
p-Ureidobenzenearsonic acid
Amabevan
Histocarb
Kutan
N-Carbamoylarsanilic acid
Carb-O-Sep
Carbarsone [INN]
4-Ureidophenylarsonic acid
Carbarsonum
p-Carbamidobenzenearsonic acid
Arsanilic acid, N-carbamoyl-
4-Ureidobenzolarsonsaeure
N-Carbamyl arsanilic acid
Carbarson [INN-Spanish]
Carbarsonum [INN-Latin]
[4-(carbamoylamino)phenyl]arsonic acid
4-Carbamylaminophenylarsonic acid
p-Carbamidophenylarsonic acid
NSC 32868
4-Ureido-1-phenylarsonic acid
Benzenearsonic acid, p-ureido-
Carbasone
Carbarsone [USP:INN]
Histocarb-sol.
Histocarb-Soluble
UNII-8PK70TXE1T
EINECS 204-484-6
Kyselina N-karbamylarsanilova
Kyselina N-karbamylarsanilova [Czech]
BRN 2940926
DTXSID4020246
AI3-17288
CARBARSONE [MI]
NSC-32868
CARBARSONE [MART.]
CARBARSONE [WHO-DD]
8PK70TXE1T
Carbamidophenyl-p-arsonic acid
DTXCID80246
CARBARSONE [GREEN BOOK]
(4-((Aminocarbonyl)amino)phenyl)arsonic acid
Arsonic acid, (4-((aminocarbonyl)amino)phenyl)-
3-16-00-01112 (Beilstein Handbook Reference)
[4-[(AMINOCARBONYL)AMINO]PHENYL]ARSONIC ACID
NCGC00016374-02
Aminarsonum
CAS-121-59-5
Carbarsone (USP:INN)
Carbarson (INN-Spanish)
Carbarsonum (INN-Latin)
{4-[(aminocarbonyl)amino]phenyl}arsonic acid
CARBARSONE (MART.)
Arsonic acid, [4-[(aminocarbonyl)amino]phenyl]-
Histocarb (VAN)
(4-(Aminocarbonyl-amino)phenyl) arsonate
[4-(Aminocarbonyl-amino)phenyl] arsonate
Carbaminophenyl-p-arsonic acid
p-Carbamino phenyl arsonic acid
(4-(Aminocarbonyl-amino)phenyl) arsonic acid
[4-(Aminocarbonyl-amino)phenyl] arsonic acid
4-Ureidobenzenearsonic acid
Carbason
CARBARZONE
Prestwick0_000413
Prestwick1_000413
Prestwick2_000413
Prestwick3_000413
WLN: ZVMR D-AS-QQO
BSPBio_000366
MLS000728528
SCHEMBL300590
SPBio_002305
BPBio1_000404
CHEMBL1331366
CHEBI:94806
WWXBHTZSYYGCSG-UHFFFAOYSA-N
HMS1569C08
HMS2096C08
HMS2225A09
HMS3346K01
HMS3713C08
Pharmakon1600-01503868
NSC32868
Tox21_110404
Tox21_201049
NSC759884
AKOS040744598
Tox21_110404_1
CCG-213223
DB11382
FC63874
NSC-759884
NCGC00016374-01
NCGC00016374-03
NCGC00016374-05
NCGC00091889-01
NCGC00258602-01
NCI60_002860
SMR000445643
HY-121067
AB00513834
CS-0079407
NS00079209
E70430
AB00513834_08
SR-01000777573
Q5037838
SR-01000777573-2
BRD-K94848716-001-11-6
204-484-6