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Piribedil

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Identification
Molecular formula
C17H19NO
CAS number
3605-01-4
IUPAC name
4,4-diphenyl-1-(1-piperidyl)but-3-en-2-one
State
State

At room temperature, Piribedil is typically in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
103.00
Melting point (Kelvin)
376.15
Boiling point (Celsius)
433.15
Boiling point (Kelvin)
706.30
General information
Molecular weight
298.41g/mol
Molar mass
298.4140g/mol
Density
1.1205g/cm3
Appearence

Piribedil appears as a crystalline solid. It is usually colorless to pale yellow in appearance.

Comment on solubility

Solubility of 4,4-diphenyl-1-(1-piperidyl)but-3-en-2-one

The solubility of 4,4-diphenyl-1-(1-piperidyl)but-3-en-2-one is an intriguing topic due to its unique molecular structure and properties. This compound can be categorized as a ketone due to the presence of the carbonyl group, which typically influences its solubility profile.

Factors Influencing Solubility

In assessing the solubility of this compound, several factors come into play:

  • Polarity: The carbonyl group (C=O) introduces some polarity, affecting how well the compound can dissolve in polar solvents.
  • Hydrophobic Aromatic Rings: The two phenyl groups contribute significant hydrophobic characteristics, likely reducing solubility in water.
  • Alkyl Chain Length: The butenyl side chain may also influence solubility, as longer chains can lead to greater hydrophobic interactions.

Solubility Characteristics

This compound is expected to be:

  • Slightly soluble in water: Due to the polar carbonyl group, there may be limited interaction with water molecules.
  • More soluble in organic solvents: Compounds like ethanol, acetone, and dimethyl sulfoxide (DMSO) are likely to dissolve it more effectively because of their ability to interact with the hydrophobic regions.

In conclusion, the solubility of 4,4-diphenyl-1-(1-piperidyl)but-3-en-2-one is influenced by both its polar and non-polar features, leading to its preferential dissolution in organic solvents rather than in aqueous environments. This intricate balance of polarity highlights the fascinating nature of chemical solubility!

Interesting facts

Interesting Facts about 4,4-Diphenyl-1-(1-piperidyl)but-3-en-2-one

4,4-Diphenyl-1-(1-piperidyl)but-3-en-2-one, commonly referred to as a β-dicarbonyl compound, is an intriguing molecule that showcases a combination of both structural complexity and biological activity. Here are some fascinating insights about this compound:

  • Structural Characteristics: This compound features two phenyl groups, which are vital for its stability and reactivity. The presence of the piperidine ring enhances its potential for interactions with biological targets.
  • Reactivity: The enone functional group in the structure makes it susceptible to nucleophilic attack, opening pathways for various chemical reactions, such as Michael addition.
  • Biological Activity: Compounds related to this structure have shown potential as pharmaceuticals, with activities ranging from antimicrobial to anticancer properties. Researchers are always exploring its capabilities in medicinal applications.
  • Versatility: Its unique structure allows it to be used as a precursor in the synthesis of other compounds, making it a valuable substrate in organic chemistry.
  • Applications in Research: The study of β-dicarbonyl compounds like this one is crucial in understanding various biochemical pathways and can contribute to the development of new therapeutic agents.

As you delve deeper into the world of organic compounds, 4,4-diphenyl-1-(1-piperidyl)but-3-en-2-one serves as a splendid example of how chemical diversity can lead to exciting applications in science and medicine. Exploring its properties may reveal even greater potential, making it a noteworthy subject in ongoing research.

Synonyms
BRN 1581008
3-BUTEN-2-ONE, 4,4-DIPHENYL-1-PIPERIDINO-
4,4-Diphenyl-1-piperidino-3-buten-2-one
3-Buten-2-one, 4,4-diphenyl-1-(1-piperidinyl)-
1866-05-3
DTXSID70171918
5-20-02-00378 (Beilstein Handbook Reference)
DTXCID4094409